Product image of Metronidazol Aurovitas (Metronidazole) supplied by GNH India

Metronidazol Aurovitas

Active Ingredient:
Metronidazole
Origin:
EU

Metronidazol Aurovitas (Metronidazole)

Metronidazole, the active ingredient in Metronidazol Aurovitas, is a nitroimidazole antibiotic presented as an oral dosage form for systemic use. It treats infections caused by anaerobic bacteria and certain protozoa in adult and pediatric patients as prescribed by a healthcare professional.

GNH India supplies Metronidazol Aurovitas as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aurovitas Pharma Polska Sp. Z O.O

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Indications & Clinical Uses

Metronidazol Aurovitas is indicated for infections where anaerobic bacteria or susceptible protozoa are involved.

  • Bacterial vaginosis: restores normal vaginal flora by eradicating anaerobic pathogens.
  • Trichomoniasis: eliminates Trichomonas vaginalis, relieving symptoms and preventing transmission.
  • Amoebiasis: treats intestinal Entamoeba histolytica infection, reducing dysentery.
  • Giardiasis: clears Giardia lamblia from the gastrointestinal tract.
  • Anaerobic bacterial infections (including Clostridioides difficile): controls toxin‑producing anaerobes in the gut and other sites.

How It Works

  • Metronidazole enters susceptible anaerobic microorganisms and is reduced by intracellular electron transport proteins, forming nitro radical anions. These reactive intermediates damage DNA, inhibit nucleic acid synthesis, and disrupt essential metabolic pathways, leading to cell death of anaerobic bacteria and protozoa.

Side Effects

Metronidazol Aurovitas may cause a range of adverse reactions.

Common Side Effects

  • Nausea: mild to moderate upset stomach.
  • Metallic taste: transient alteration of taste perception.
  • Diarrhea: loose stools that may be self‑limiting.
  • Headache: mild to moderate cranial discomfort.

Serious or Rare Side Effects

  • Seizures: convulsive episodes requiring immediate medical attention.
  • Peripheral neuropathy: tingling or numbness in extremities.
  • Severe allergic reaction: rash, swelling, or anaphylaxis.
  • Stevens‑Johnson syndrome: serious skin and mucous membrane disorder.
  • Pseudomembranous colitis: severe colonic inflammation.
  • Hepatotoxicity: elevated liver enzymes or liver injury.

Precautions & Warnings

Before prescribing Metronidazol Aurovitas, clinicians should consider several safety factors.

  • Renal function: assess kidney status, especially in patients with impairment.
  • Hepatic function: evaluate liver health, as metabolism occurs hepatically.
  • Alcohol consumption: advise avoidance of alcohol to prevent disulfiram‑like reactions.
  • Pregnancy status: weigh benefits against potential risks; use only if clearly needed.
  • Superinfection risk: monitor for overgrowth of non‑susceptible organisms.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Metronidazol Aurovitas can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Alcohol: may cause severe flushing, nausea, and tachycardia.
  • Warfarin: potentiates anticoagulant effect, increasing bleeding risk.
  • Lithium: can raise lithium levels, leading to toxicity.

Moderate Interactions (Monitor Closely)

  • Phenytoin: may reduce metronidazole concentrations, decreasing effectiveness.
  • Cimetidine: can increase metronidazole plasma levels, heightening adverse effects.

Frequently Asked Questions

Metronidazol Aurovitas is prescribed for bacterial vaginosis, trichomoniasis, amoebiasis, giardiasis, and a range of anaerobic bacterial infections such as Clostridioides difficile. It targets organisms that thrive in low‑oxygen environments and certain protozoa, helping to eliminate the infection and relieve symptoms.

Metronidazole penetrates anaerobic microorganisms and is reduced by their internal electron transport proteins. This reduction creates nitro radical anions that damage DNA and inhibit nucleic acid synthesis, ultimately killing the bacteria or protozoa that cause the infection.

The specific dose and treatment duration of Metronidazol Aurovitas are determined by the prescribing clinician based on the infection type, severity, patient age, weight, and renal or hepatic function. Patients should follow the exact regimen provided by their healthcare professional.

Safety in pregnancy and lactation has not been definitively established for Metronidazol Aurovitas. Healthcare providers weigh potential benefits against possible risks before prescribing it to pregnant or nursing individuals. Women should discuss their situation with a qualified professional.

To request Metronidazol Aurovitas, submit an enquiry on the product page at gnhindia.com indicating the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Metronidazol Aurovitas belongs to the nitroimidazole class, offering broad activity against anaerobic bacteria and certain protozoa. Compared with alternatives such as clindamycin or carbapenems, metronidazole provides a convenient oral option with a well‑characterized safety profile, though drug‑specific resistance patterns and patient factors guide final selection.

Metronidazol Aurovitas should be stored at room temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight, and excessive heat to maintain its stability and potency throughout its shelf life.

Metronidazol Aurovitas is taken orally, usually with or without food as directed by the prescriber. The tablets should be swallowed whole with a glass of water and not chewed or crushed unless specifically instructed.

Serious risks include seizures, peripheral neuropathy, severe allergic reactions (including anaphylaxis), Stevens‑Johnson syndrome, pseudomembranous colitis, and liver toxicity. Patients should seek immediate medical attention if they experience neurological symptoms, rash, or signs of severe infection.

Metronidazol Aurovitas is contraindicated in individuals with a known hypersensitivity to metronidazole or other nitroimidazole derivatives. Caution is also advised for patients with severe hepatic impairment, those who consume alcohol heavily, and individuals with a history of severe neurological reactions to the drug.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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