Product image of Metronidazol B. Braun (Metronidazole) supplied by GNH India

Metronidazol B. Braun

Active Ingredient:
Metronidazole
Origin:
EU

Metronidazol B. Braun (Metronidazole)

Metronidazole, the active ingredient in Metronidazol B. Braun, is a nitroimidazole presented as an injectable solution for intravenous use. It treats anaerobic bacterial infections, intra‑abdominal infections, pelvic inflammatory disease, bacterial sepsis and Clostridioides difficile infection in adult patients.

GNH India supplies Metronidazol B. Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

B.Braun Melsungen Ag

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Indications & Clinical Uses

  • Metronidazole is a nitroimidazole antibiotic used to treat infections caused by anaerobic bacteria.
  • Anaerobic bacterial infections: eradicates anaerobic organisms and resolves infection.
  • Intra‑abdominal infections: controls polymicrobial intra‑abdominal sepsis.
  • Pelvic inflammatory disease: reduces pelvic infection severity.
  • Bacterial sepsis: provides systemic coverage against anaerobes.
  • Clostridioides difficile infection: treats mild to moderate C. difficile colitis.

How It Works

  • Metronidazole enters anaerobic microorganisms and is reduced by ferredoxin‑type proteins to generate nitro radical anions. These reactive intermediates damage DNA, inhibit nucleic acid synthesis, and disrupt essential metabolic pathways, leading to bacterial cell death while sparing aerobic cells.

Side Effects

Metronidazole may cause a range of adverse reactions.

Common Side Effects

  • Nausea
  • Metallic taste
  • Headache
  • Diarrhea

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis)
  • Seizures
  • Peripheral neuropathy
  • Hepatic dysfunction

Precautions & Warnings

  • Use Metronidazol B. Braun with appropriate clinical vigilance.
  • Assess renal function: adjust use in patients with renal impairment.
  • Monitor hepatic function: watch for liver enzyme elevation.
  • Evaluate for hypersensitivity: discontinue if allergic reaction occurs.
  • Use caution in pregnancy: risk unknown, weigh benefits and risks.
  • Avoid in patients with known metronidazole hypersensitivity.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Metronidazol B. Braun can interact with several medicines.

Major Interactions (Avoid)

  • Alcohol: may cause a disulfiram‑like reaction.
  • Warfarin: enhanced anticoagulant effect, monitor INR.
  • Lithium: increased lithium toxicity.

Moderate Interactions (Monitor Closely)

  • Carbamazepine: enzyme induction may reduce metronidazole levels.
  • Phenytoin: similar enzyme‑inducing effect, monitor therapeutic response.

Frequently Asked Questions

Metronidazol B. Braun is an intravenous metronidazole formulation indicated for the treatment of anaerobic bacterial infections, intra‑abdominal infections, pelvic inflammatory disease, bacterial sepsis and mild to moderate Clostridioides difficile infection in adult patients.

Metronidazole is reduced inside anaerobic microorganisms to form nitro radical anions. These reactive species damage bacterial DNA and inhibit nucleic acid synthesis, leading to cell death while having minimal effect on aerobic cells.

The dosage and infusion rate of Metronidazol B. Braun are determined by the prescribing clinician based on the infection type, severity, patient weight, renal and hepatic function, and local treatment guidelines.

Safety data for metronidazole in pregnancy are limited and the product is classified as pregnancy category unknown. It should be used only if the potential benefit justifies the potential risk to the fetus. Caution is also advised during breastfeeding, and a healthcare professional should evaluate the risk‑benefit ratio.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where required) and any necessary import documentation.

Metronidazol B. Braun delivers the same active ingredient as other metronidazole products but in an injectable form, allowing rapid systemic exposure for severe infections. Compared with oral formulations, the IV route provides higher plasma concentrations, which can be advantageous in critically ill patients or when oral absorption is compromised.

The product should be stored refrigerated at 2‑8 °C, protected from light, and must not be frozen or shaken. Prior to administration, inspect the solution for particulate matter and ensure the vial is within its expiry date.

Metronidazol B. Braun is administered by intravenous infusion. The solution is typically diluted in compatible IV fluids and infused over a period dictated by the prescribing clinician, taking into account the infection severity and patient tolerance.

Serious risks include severe allergic reactions such as anaphylaxis, seizures, peripheral neuropathy, and hepatic dysfunction. Patients should be monitored for signs of these events, and treatment should be discontinued immediately if they occur.

Metronidazol B. Braun is contraindicated in patients with a known hypersensitivity to metronidazole or any component of the formulation. Caution is also advised in individuals with severe hepatic impairment, and it should be avoided in patients who are actively consuming alcohol due to the risk of a disulfiram‑like reaction.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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