Product image of Metronidazol B Infomed Fluids (Metronidazole) supplied by GNH India

Metronidazol B Infomed Fluids

Active Ingredient:
Metronidazole
Origin:
EU

Metronidazol B Infomed Fluids (Metronidazole)

Metronidazole, the active ingredient in Metronidazol B Infomed Fluids, is a nitroimidazole antibiotic presented as an injectable solution for intravenous use. It is employed to treat anaerobic bacterial infections and certain protozoal diseases in both adult and pediatric patients, including severe intra‑abdominal infections and bacterial vaginosis.

GNH India supplies Metronidazol B Infomed Fluids as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory support for cross‑border distribution.

Manufacturer / TM Owner

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Indications & Clinical Uses

Metronidazole is used to treat infections caused by anaerobic bacteria and certain protozoa.

  • Anaerobic bacterial infections: eradicates susceptible anaerobes, reducing infection severity.
  • Clostridioides difficile infection: suppresses toxin‑producing C. difficile, aiding clinical recovery.
  • Bacterial vaginosis: restores normal vaginal flora by targeting anaerobic pathogens.
  • Amoebiasis: eliminates Entamoeba histolytica trophozoites, preventing tissue invasion.
  • Giardiasis: clears Giardia lamblia trophozoites, relieving gastrointestinal symptoms.

How It Works

  • Metronidazole enters anaerobic microorganisms and is reduced by intracellular ferredoxin proteins, generating nitro radicals. These reactive intermediates damage DNA, inhibit nucleic acid synthesis, and disrupt essential metabolic pathways, leading to cell death of susceptible bacteria and protozoa.

Side Effects

Metronidazole may cause a range of adverse reactions.

Common Side Effects

  • Nausea: mild to moderate upset stomach.
  • Metallic taste: transient alteration of taste perception.
  • Headache: occasional mild to moderate headache.
  • Diarrhea: loose stools during therapy.

Serious or Rare Side Effects

  • Seizures: rare neurologic events, especially with high doses.
  • Peripheral neuropathy: tingling or numbness in extremities.
  • Severe allergic reactions: anaphylaxis or angioedema.
  • Stevens‑Johnson syndrome: severe skin and mucosal reactions.

Precautions & Warnings

Metronidazole requires careful consideration of patient factors and handling.

  • Renal impairment: adjust therapy based on renal function.
  • Hepatic disease: monitor liver enzymes during treatment.
  • Alcohol consumption: avoid due to disulfiram‑like reaction.
  • Pregnancy: use only if benefits outweigh potential risks.
  • Concurrent use with alcohol‑containing solutions: avoid to prevent adverse reactions.
  • Store at ambient temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Metronidazole can interact with several medicines, requiring vigilance.

Major Interactions (Avoid)

  • Alcohol: may cause severe disulfiram‑like reaction.
  • Warfarin: may increase anticoagulant effect, raising bleeding risk.
  • Lithium: may elevate lithium concentrations, risking toxicity.
  • Cimetidine: may increase metronidazole plasma levels.

Moderate Interactions (Monitor Closely)

  • Phenobarbital: may reduce metronidazole concentrations.
  • Carbamazepine: may lower efficacy of metronidazole.
  • Phenytoin: may decrease metronidazole plasma levels.

Frequently Asked Questions

Metronidazol B Infomed Fluids contains metronidazole, which is indicated for the treatment of anaerobic bacterial infections, Clostridioides difficile colitis, bacterial vaginosis, amoebiasis, and giardiasis. It is administered intravenously to achieve rapid systemic concentrations in patients requiring prompt antimicrobial therapy.

Metronidazole is reduced inside anaerobic cells, forming nitro radicals that damage DNA and inhibit nucleic acid synthesis. This disruption leads to loss of cellular function and death of susceptible bacteria and protozoa, making it effective against a broad range of anaerobic pathogens.

The specific dose and infusion rate are determined by the prescribing clinician based on the infection type, severity, patient weight, renal and hepatic function, and local treatment guidelines. Healthcare professionals should follow institutional protocols and adjust as needed.

Safety data are limited; metronidazole should be used in pregnancy only when the potential benefit justifies any potential risk to the fetus. It is excreted in breast milk, so breastfeeding mothers should consult their healthcare provider before treatment.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Metronidazole is a nitroimidazole that specifically targets anaerobic organisms, offering rapid bactericidal activity. Compared with broad‑spectrum agents like clindamycin, it has a narrower spectrum but fewer concerns about Clostridioides difficile overgrowth. Choice depends on pathogen susceptibility, infection site, and patient tolerance.

Store the product at ambient temperature, preferably below 25 °C, in its original packaging. Protect it from direct light, moisture, and extreme temperature fluctuations. Do not freeze the solution, and discard any product that appears discolored or contains particles.

The medication is supplied as a sterile injectable solution for intravenous infusion. It should be administered by a qualified healthcare professional using aseptic technique, typically diluted in compatible IV fluids and infused over the period recommended by the prescriber.

Serious adverse events include seizures, peripheral neuropathy, severe allergic reactions such as anaphylaxis, and rare skin disorders like Stevens‑Johnson syndrome. Patients should be monitored for neurological symptoms, skin changes, or signs of hypersensitivity, and therapy should be discontinued if these occur.

Metronidazole is contraindicated in patients with a known hypersensitivity to metronidazole or other nitroimidazoles. Caution is also advised for individuals with severe hepatic impairment, those receiving concurrent disulfiram therapy, and patients with a history of severe neurologic reactions to the drug.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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