Product image of Metronidazol Baxter (Metronidazole) supplied by GNH India

Metronidazol Baxter

Active Ingredient:
Metronidazole
Origin:
EU

Metronidazol Baxter (Metronidazole)

Metronidazole, the active ingredient in Metronidazol Baxter, is a nitroimidazole antibiotic presented as an intravenous solution for intravenous use. It treats anaerobic bacterial infections and certain protozoal infections in adult patients.
GNH India supplies Metronidazol Baxter as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Baxter Medical Ab

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Indications & Clinical Uses

Metronidazole is used to treat infections caused by anaerobic bacteria and susceptible protozoa.

  • Anaerobic bacterial infections: eradicates mixed‑flora infections where oxygen‑tolerant organisms predominate.
  • Intra‑abdominal infections: resolves peritonitis and abscesses involving anaerobes.
  • Pelvic inflammatory disease: eliminates causative anaerobic pathogens in the upper genital tract.
  • Bacterial vaginosis: restores normal vaginal flora by targeting Gardnerella and related organisms.
  • Trichomoniasis: kills Trichomonas vaginalis, relieving symptoms and preventing transmission.
  • Clostridioides difficile‑associated diarrhea: reduces toxin‑producing bacteria and alleviates severe colitis.

How It Works

  • Metronidazole is reduced by anaerobic microorganisms to reactive nitro radicals that damage DNA, inhibit nucleic acid synthesis, and disrupt essential metabolic pathways, leading to irreversible bacterial and protozoal cell death while sparing aerobic cells.

Side Effects

Metronidazole may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Nausea: transient gastrointestinal upset.
  • Metallic taste: temporary alteration of taste perception.
  • Headache: mild to moderate cephalic discomfort.
  • Diarrhea: loose stools occurring during therapy.

Serious or Rare Side Effects

  • Seizures: neurologic events requiring immediate medical attention.
  • Peripheral neuropathy: tingling or numbness of extremities.
  • Severe allergic reactions: rash, angioedema, or anaphylaxis.

Precautions & Warnings

Metronidazole requires careful patient assessment and monitoring.

  • Renal function: evaluate kidney status before and during therapy.
  • Hepatic function: monitor liver enzymes, especially in prolonged courses.
  • Alcohol consumption: avoid due to disulfiram‑like reaction.
  • Pregnancy: use only if benefits outweigh potential risks.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze.

Avoid Interactions

Metronidazole can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Alcohol: precipitates severe flushing, tachycardia, and hypotension.
  • Warfarin: may potentiate anticoagulant effect, increasing bleeding risk.
  • Lithium: can raise lithium concentrations, leading to toxicity.

Moderate Interactions (Monitor Closely)

  • Phenytoin: may reduce phenytoin levels, decreasing seizure control.
  • Cimetidine: can increase metronidazole plasma concentrations, enhancing adverse effects.

Frequently Asked Questions

Metronidazol Baxter is indicated for anaerobic bacterial infections, intra‑abdominal infections, pelvic inflammatory disease, bacterial vaginosis, trichomoniasis, and Clostridioides difficile‑associated diarrhea. It targets organisms that thrive in low‑oxygen environments.

Metronidazole is taken up by anaerobic microbes and reduced to reactive nitro radicals. These radicals damage microbial DNA and inhibit nucleic acid synthesis, leading to cell death while sparing aerobic cells.

The specific dose and infusion rate are determined by the prescribing clinician based on infection type, severity, patient weight, and renal or hepatic function. Dosing should follow the prescriber’s order.

Safety data are limited; the product is classified as pregnancy category unknown. It should be used only if the potential benefit justifies any potential risk to the fetus. Caution is also advised when breastfeeding, as the drug can be excreted in milk.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Metronidazol Baxter shares the same class mechanism as other nitroimidazoles such as tinidazole. It offers comparable efficacy for anaerobic and protozoal infections, with a well‑characterized safety profile. Choice often depends on formulation, dosing convenience, and local resistance patterns.

Store the intravenous solution at 2‑8 °C in a refrigerator. Protect it from light, do not freeze, and keep the vial in its original packaging until use to maintain stability.

Metronidazol Baxter is given by intravenous infusion. The infusion rate and duration are set by the treating physician, typically over 30‑60 minutes, and may be repeated depending on the clinical response.

Serious adverse events include seizures, peripheral neuropathy, severe allergic reactions (anaphylaxis), and rare cases of Stevens‑Johnson syndrome. Prompt medical evaluation is required if any of these symptoms develop.

Patients with known hypersensitivity to metronidazole or other nitroimidazoles should avoid the product. Caution is also advised for individuals with severe hepatic impairment, and it is contraindicated in those with a history of disulfiram‑like reactions to alcohol.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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