Product image of Metronidazol Chema (Metronidazole) supplied by GNH India

Metronidazol Chema

Active Ingredient:
Metronidazole
Origin:
EU

Metronidazol Chema (Metronidazole)

Metronidazole, the active ingredient in Metronidazol Chema, is a nitroimidazole presented as a tablet for dental use. It treats anaerobic bacterial infections and protozoal diseases such as amoebiasis, bacterial vaginosis, trichomoniasis, and related dental infections in adults.

GNH India supplies Metronidazol Chema as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Chema Elektromet Spoldzielnia Pracy

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Indications & Clinical Uses

Metronidazole is employed to manage infections caused by anaerobic bacteria and certain protozoa.

  • Amoebiasis: eradicates Entamoeba histolytica, relieving intestinal symptoms.
  • Bacterial vaginosis: eliminates Gardnerella vaginalis, restoring normal vaginal flora.
  • Trichomoniasis: clears Trichomonas vaginalis infection, reducing discharge and irritation.
  • Anaerobic bacterial infections: targets mixed‑flora infections in tissues, aiding healing.
  • Dental infections: controls anaerobic organisms in periodontal disease and post‑extraction sites.

How It Works

  • Metronidazole is reduced inside anaerobic microorganisms to reactive nitro radicals. These radicals damage DNA and inhibit nucleic acid synthesis, leading to loss of cellular replication and ultimately cell death. The selective activation in low‑oxygen environments provides targeted antimicrobial activity against susceptible bacteria and protozoa.

Side Effects

Metronidazole may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Nausea: mild to moderate upset stomach.
  • Metallic taste: transient metallic sensation in the mouth.
  • Headache: occasional dull or throbbing pain.
  • Diarrhea: loose stools during therapy.
  • Abdominal cramps: intermittent stomach discomfort.
  • Loss of appetite: reduced desire to eat.

Serious or Rare Side Effects

  • Seizures: neurological events requiring immediate care.
  • Peripheral neuropathy: tingling or numbness in extremities.
  • Severe allergic reactions: rash, swelling, or anaphylaxis.
  • Stevens‑Johnson syndrome: serious skin blistering.
  • Liver toxicity: elevated enzymes or jaundice.
  • Blood dyscrasias: neutropenia or aplastic anemia.

Precautions & Warnings

Before using Metronidazol Chema, consider the following safety measures.

  • Pregnancy: consult a healthcare provider; safety data are limited.
  • Alcohol: avoid concurrent intake to prevent a disulfiram‑like reaction.
  • Liver disease: monitor hepatic function and adjust therapy if needed.
  • Renal impairment: dose may require adjustment; monitor kidney function.
  • Drug interactions: review all concomitant medications with a pharmacist.
  • Store at ambient temperature below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Metronidazol Chema can interact with several medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Alcohol: may cause severe flushing, tachycardia, and nausea.
  • Warfarin: increased anticoagulant effect, raising bleeding risk.
  • Lithium: heightened lithium toxicity, requiring monitoring.

Moderate Interactions (Monitor Closely)

  • Oral contraceptives: reduced efficacy, consider backup method.
  • Phenytoin: possible decrease in phenytoin levels, monitor seizure control.

Frequently Asked Questions

Metronidazol Chema contains metronidazole, an antimicrobial indicated for treating anaerobic bacterial infections, amoebiasis, bacterial vaginosis, trichomoniasis, and dental infections caused by susceptible organisms. It is prescribed by healthcare professionals for these specific conditions.

Metronidazole enters anaerobic microorganisms and is reduced to nitro radicals. These reactive species damage DNA and inhibit nucleic acid synthesis, leading to bacterial or protozoal cell death while sparing most aerobic cells.

The dosage of Metronidazol Chema is determined by the prescribing clinician based on the infection type, severity, patient weight, renal and hepatic function, and local treatment guidelines. Patients should follow the exact regimen provided by their healthcare professional.

Safety data for metronidazole in pregnancy are limited, and the drug is generally used only when the potential benefit outweighs the risk. Breastfeeding mothers should consult their physician, as metronidazole can be excreted in breast milk.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and necessary import documentation.

Metronidazol Chema belongs to the nitroimidazole class, offering broad activity against anaerobic bacteria and protozoa. Compared with agents like tinidazole, it has a similar spectrum but may differ in dosing frequency and side‑effect profile. Choice of therapy depends on clinical guidelines and patient tolerance.

Store the product at ambient temperature below 25 °C, in its original packaging, and protect it from moisture and direct sunlight. Keep out of reach of children and do not use if the packaging is damaged.

Metronidazol Chema is supplied as a tablet for dental administration. It is taken orally with a full glass of water, usually with food to reduce gastrointestinal upset, unless otherwise directed by a healthcare professional.

Serious risks include seizures, peripheral neuropathy, severe allergic reactions (including anaphylaxis), Stevens‑Johnson syndrome, liver toxicity, and blood dyscrasias such as neutropenia. Patients should seek immediate medical attention if they experience neurological symptoms, rash, or signs of liver injury.

Individuals with known hypersensitivity to metronidazole or other nitroimidazoles should avoid the product. Patients with severe hepatic impairment, those taking interacting medications such as warfarin without monitoring, and pregnant women unless clearly indicated should not use it without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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