Product image of Metronidazol Dak (Metronidazole) supplied by GNH India

Metronidazol Dak

Active Ingredient:
Metronidazole
Origin:
EU

Metronidazol Dak (Metronidazole)

Metronidazole, the active ingredient in Metronidazol Dak, is a nitroimidazole antibiotic presented as an oral tablet for oral use. It treats a range of anaerobic bacterial and protozoal infections in adult and pediatric patients as prescribed by a healthcare professional.

GNH India supplies Metronidazol Dak as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Orifarm Healthcare A/S

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Indications & Clinical Uses

Metronidazol Dak is a nitroimidazole that targets anaerobic bacteria and susceptible protozoa across several infection types.

  • Bacterial vaginosis: eradicates the anaerobic flora responsible for the condition.
  • Trichomoniasis: eliminates Trichomonas vaginalis, relieving symptoms and preventing recurrence.
  • Amoebiasis: destroys Entamoeba histolytica trophozoites in intestinal disease.
  • Anaerobic bacterial infections: treats intra‑abdominal, pelvic, skin and soft‑tissue infections caused by obligate anaerobes.
  • Clostridioides difficile infection: reduces toxin‑producing bacteria and helps restore gut flora balance.

How It Works

  • Metronidazole is reduced within susceptible microorganisms to generate nitro radical anions. These reactive intermediates damage DNA, inhibit nucleic acid synthesis, and disrupt essential metabolic pathways, leading to cell death of anaerobic bacteria and protozoa while sparing most aerobic host cells.

Side Effects

Metronidazol Dak may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Metallic taste: transient alteration of taste perception.
  • Headache: mild, often resolves without intervention.
  • Diarrhea: loose stools that usually improve with continued therapy.

Serious or Rare Side Effects

  • Seizures: rare neurologic events requiring immediate medical attention.
  • Peripheral neuropathy: tingling or numbness in extremities, potentially irreversible.
  • Severe allergic reactions: rash, itching, swelling, or anaphylaxis.
  • Hepatotoxicity: elevated liver enzymes indicating liver stress.
  • Stevens‑Johnson syndrome: severe skin and mucous membrane reaction.

Precautions & Warnings

Before prescribing Metronidazol Dak, clinicians should consider several safety factors.

  • Pregnancy: consult a healthcare provider as safety data are limited, especially in the first trimester.
  • Breastfeeding: evaluate risk versus benefit because the drug is excreted in milk.
  • Liver disease: adjust therapy if hepatic impairment is present.
  • Alcohol consumption: advise patients to avoid alcohol due to a disulfiram‑like reaction.
  • Neurologic disorders: monitor for signs of peripheral neuropathy or seizures.
  • Store at ambient temperature: keep below 25°C in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Metronidazol Dak can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Disulfiram: concurrent use may cause severe flushing, tachycardia, and hypotension.
  • Warfarin: increased anticoagulant effect, requiring close INR monitoring.

Moderate Interactions (Monitor Closely)

  • Lithium: may raise serum lithium levels, necessitating periodic checks.
  • Cimetidine: can raise metronidazole plasma concentrations, watch for toxicity.
  • Alcohol-containing products: risk of a disulfiram‑like reaction; advise abstinence during therapy.

Frequently Asked Questions

Metronidazol Dak contains metronidazole, an antibiotic and antiprotozoal agent used to treat bacterial vaginosis, trichomoniasis, amoebiasis, a variety of anaerobic bacterial infections, and Clostridioides difficile infection. It is prescribed by a qualified healthcare professional based on the specific infection and patient characteristics.

Metronidazole enters susceptible microorganisms and is reduced to reactive nitro radical anions. These intermediates bind to DNA and other critical macromolecules, disrupting nucleic acid synthesis and leading to cell death. The process selectively targets anaerobic bacteria and certain protozoa while sparing most aerobic human cells.

The dosage of Metronidazol Dak is individualized by the prescribing clinician according to the infection being treated, patient age, weight, renal and hepatic function, and other clinical factors. Patients should follow the exact regimen written on their prescription and not alter the dose without medical advice.

Safety data for metronidazole in pregnancy are limited, and the drug is generally avoided in the first trimester unless the benefits outweigh the risks. It is excreted in breast milk, so clinicians assess the risk‑benefit ratio before recommending use while breastfeeding. Consultation with a healthcare provider is essential.

To place an order, submit an enquiry on the Metronidazol Dak product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Metronidazol Dak is often preferred for anaerobic infections because of its broad spectrum against obligate anaerobes and protozoa, oral availability, and cost‑effectiveness. Alternatives such as clindamycin or tinidazole may be used when metronidazole intolerance occurs, but they can have different side‑effect profiles and resistance patterns.

Store Metronidazol Dak at ambient temperature, preferably below 25 °C, in the original packaging to protect it from moisture and direct sunlight. Keep the container tightly closed and out of reach of children. No refrigeration is required for this oral tablet formulation.

Metronidazol Dak is taken orally with a full glass of water. It may be taken with or without food, although taking it with meals can reduce gastrointestinal upset. The tablet should be swallowed whole; it should not be crushed, chewed, or dissolved unless specifically instructed by a healthcare professional.

Serious adverse events include seizures, peripheral neuropathy, severe allergic reactions such as anaphylaxis, and hepatotoxicity. Patients should seek immediate medical attention if they experience neurological symptoms, rash with swelling, or signs of liver dysfunction such as jaundice or dark urine.

Metronidazol Dak should be avoided in individuals with a known hypersensitivity to metronidazole or other nitroimidazole compounds. It is also contraindicated in patients with severe hepatic impairment and should be used with caution during early pregnancy. Clinicians must evaluate each patient’s medical history before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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