Product image of Metronidazol Eql Pharma (Metronidazole) supplied by GNH India

Metronidazol Eql Pharma

Active Ingredient:
Metronidazole
Origin:
EU

Metronidazol Eql Pharma (Metronidazole)

Metronidazole, the active ingredient in Metronidazol Eql Pharma, is a nitroimidazole antibiotic presented as an oral dosage form for systemic use. It treats infections caused by susceptible anaerobic bacteria and certain protozoa in adult patients, including conditions of the gastrointestinal, genitourinary and skin systems.

GNH India supplies Metronidazol Eql Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance across global markets.

Manufacturer / TM Owner

Eql Pharma Ab

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Indications & Clinical Uses

Metronidazole is used to treat infections caused by anaerobic bacteria and protozoal organisms.

  • Anaerobic bacterial infections: effective against infections caused by anaerobic organisms, reducing bacterial load.
  • Bacterial vaginosis: restores normal vaginal flora by eliminating over‑growth of anaerobic bacteria.
  • Trichomoniasis: eradicates Trichomonas vaginalis, relieving symptoms and preventing transmission.
  • Amoebiasis: eliminates intestinal Entamoeba histolytica, treating dysentery and liver abscesses.
  • Clostridioides difficile infection (adjunct therapy): used alongside standard therapy to reduce toxin‑producing bacteria.

How It Works

  • Metronidazole is reduced within susceptible microorganisms to generate nitro radical anions. These reactive intermediates damage DNA and inhibit nucleic acid synthesis, leading to cell death of anaerobic bacteria and certain protozoa while sparing aerobic cells.

Side Effects

Metronidazole may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Nausea: mild to moderate upset stomach.
  • Metallic taste: persistent metallic sensation in the mouth.
  • Headache: occasional throbbing headache.
  • Diarrhea: loose stools or increased frequency.
  • Abdominal cramps: intermittent stomach discomfort.
  • Loss of appetite: reduced desire to eat.

Serious or Rare Side Effects

  • Seizures: convulsions, especially with high plasma levels.
  • Peripheral neuropathy: tingling or numbness in extremities.
  • Severe allergic reactions: rash, swelling, anaphylaxis.
  • Stevens‑Johnson syndrome: severe skin blistering.
  • Liver toxicity: jaundice or elevated liver enzymes.
  • Neutropenia: marked reduction in white blood cells.

Precautions & Warnings

Before prescribing metronidazole, consider the following precautions.

  • Pregnancy: consult a healthcare provider; safety category is not established.
  • Alcohol consumption: avoid alcohol to prevent a disulfiram‑like reaction.
  • Renal impairment: dose may need adjustment in patients with reduced kidney function.
  • Hepatic disease: monitor liver function and use with caution.
  • Drug interactions: review all concomitant medications for potential interactions.
  • Store at ambient temperature: keep below 25 °C in the original packaging, protected from moisture.

Avoid Interactions

Metronidazole can interact with several medicines; interactions are classified by clinical significance.

Major Interactions (Avoid)

  • Alcohol: may cause severe nausea, vomiting, and flushing.
  • Warfarin: increased anticoagulant effect, risk of bleeding.
  • Lithium: heightened risk of lithium toxicity.
  • Cimetidine: may raise metronidazole plasma concentrations.
  • Phenobarbital: can reduce metronidazole efficacy.

Moderate Interactions (Monitor Closely)

  • Erythromycin: possible increase in metronidazole levels.
  • Benzodiazepines: enhanced sedative effect.
  • Phenytoin: may decrease metronidazole concentrations.
  • Oral contraceptives: potential reduction in contraceptive effectiveness.

Frequently Asked Questions

Metronidazol Eql Pharma contains metronidazole, a prescription oral antibiotic indicated for anaerobic bacterial infections, bacterial vaginosis, trichomoniasis, amoebiasis, and as adjunct therapy for Clostridioides difficile infection. It targets susceptible microorganisms to eradicate the infection and relieve associated symptoms.

Metronidazole enters susceptible anaerobic bacteria and protozoa, where it is reduced to reactive nitro radical anions. These intermediates damage microbial DNA and inhibit nucleic acid synthesis, leading to cell death while sparing most aerobic cells.

The appropriate dose is set by the prescribing clinician based on the specific infection, its severity, the patient’s age, weight, renal and hepatic function, and any concomitant therapies. Exact dosing regimens are not provided here.

Safety in pregnancy and lactation has not been definitively established. Use only if the potential benefit outweighs the risk, and discuss with a healthcare professional. Breastfeeding mothers should also seek medical advice before use.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Metronidazole is a first‑line nitroimidazole for many anaerobic and protozoal infections. Alternatives such as tinidazole have similar spectra but longer half‑life, allowing once‑daily dosing. Choice depends on infection type, resistance patterns, patient tolerance, and clinician preference.

Store the product at room temperature, below 25 °C, in its original container. Protect from moisture and direct sunlight. Do not refrigerate or freeze unless otherwise instructed on the label.

The medication is taken orally, usually as tablets or capsules, with or without food as directed by the prescriber. Swallow whole with a full glass of water; do not crush or chew unless the formulation specifically allows it.

Serious adverse events include seizures, peripheral neuropathy, severe allergic reactions (including anaphylaxis), Stevens‑Johnson syndrome, liver toxicity, and neutropenia. Patients should seek immediate medical attention if they experience neurological symptoms, rash, or signs of liver dysfunction.

Individuals with known hypersensitivity to metronidazole or other nitroimidazoles should avoid it. Patients with severe hepatic impairment, those who consume alcohol, and those taking certain interacting medications (e.g., warfarin, lithium) should use it only under close medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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