Product image of Metronidazol Fresenius (Metronidazole) supplied by GNH India

Metronidazol Fresenius

Active Ingredient:
Metronidazole
Origin:
EU

Metronidazol Fresenius (Metronidazole)

Metronidazole, the active ingredient in Metronidazol Fresenius, is a nitroimidazole antibiotic presented as an intravenous solution for intravenous use. It treats anaerobic bacterial infections and certain protozoal infections in adult patients. GNH India supplies Metronidazol Fresenius as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Fresenius Kabi Deutschland Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Metronidazole is a nitroimidazole antibiotic used to treat infections caused by anaerobic bacteria and specific protozoa.

  • Anaerobic bacterial infections: effective against mixed anaerobic infections in abdominal, pelvic and soft‑tissue sites.
  • Intra‑abdominal infections: helps resolve peritonitis and postoperative intra‑abdominal sepsis.
  • Pelvic inflammatory disease: targets anaerobic organisms contributing to PID.
  • Bacterial vaginosis: reduces overgrowth of anaerobic vaginal flora.
  • Protozoal infections such as giardiasis and trichomoniasis: eradicates the causative protozoa.

How It Works

  • Metronidazole is reduced within anaerobic microorganisms to reactive nitro radicals that damage DNA and inhibit nucleic acid synthesis, leading to cell death. The reduction occurs preferentially in low‑oxygen environments, allowing selective toxicity against anaerobic bacteria and certain protozoa while sparing aerobic host cells.

Side Effects

Metronidazole may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Nausea: mild to moderate upset stomach.
  • Metallic taste: transient alteration of taste perception.
  • Headache: occasional mild headache.
  • Diarrhea: loose stools during therapy.

Serious or Rare Side Effects

  • Seizures: rare neurologic events.
  • Peripheral neuropathy: tingling or numbness in extremities.
  • Severe allergic reactions: anaphylaxis or angioedema.
  • Stevens‑Johnson syndrome: severe skin and mucous membrane reaction.

Precautions & Warnings

Metronidazole requires careful consideration of patient factors and handling.

  • Pregnancy: use only if benefits outweigh potential risks.
  • Renal impairment: monitor renal function and adjust therapy as needed.
  • Hepatic impairment: exercise caution; monitor liver enzymes.
  • Alcohol consumption: avoid during and 48 hours after treatment to prevent disulfiram‑like reaction.
  • Concurrent anticoagulants: monitor coagulation parameters for increased bleeding risk.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze.

Avoid Interactions

Metronidazole can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Alcohol: may cause severe disulfiram‑like reaction.
  • Warfarin: increased anticoagulant effect, monitor INR closely.
  • Lithium: potential rise in lithium levels, monitor serum lithium.

Moderate Interactions (Monitor Closely)

  • Cimetidine: may raise metronidazole concentrations, watch for toxicity.
  • Phenytoin: may reduce metronidazole effectiveness, assess clinical response.

Frequently Asked Questions

Metronidazol Fresenius, containing metronidazole, is used to treat anaerobic bacterial infections such as intra‑abdominal infections, pelvic inflammatory disease, bacterial vaginosis, and protozoal infections like giardiasis and trichomoniasis. It is administered intravenously in hospital settings to target organisms that thrive in low‑oxygen environments.

Metronidazole is taken up by anaerobic microorganisms and reduced to reactive nitro radicals. These radicals interact with DNA, causing strand breakage and inhibiting nucleic acid synthesis, which leads to bacterial or protozoal cell death while sparing most human cells.

The specific dose of Metronidazol Fresenius is determined by the prescribing clinician based on the infection type, severity, patient weight, renal and hepatic function, and other clinical factors. Healthcare professionals set the appropriate regimen for each individual case.

Safety data for metronidazole in pregnancy are limited, and the product is classified as pregnancy category unknown. It should only be used when the potential benefit justifies any possible risk to the fetus. Breastfeeding mothers should consult a healthcare provider, as metronidazole can be excreted in breast milk.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Metronidazol Fresenius belongs to the nitroimidazole class, which is uniquely effective against anaerobic bacteria and certain protozoa. Unlike many broad‑spectrum antibiotics, it targets organisms that thrive in low‑oxygen environments, making it the preferred choice for infections where anaerobes predominate, such as intra‑abdominal sepsis.

Metronidazol Fresenius should be stored at 2‑8 °C, kept refrigerated, protected from light, and must not be frozen or shaken. Maintain the product in its original packaging until use to preserve stability and potency.

The product is supplied as an intravenous solution and is administered by a healthcare professional through a vein, typically using a controlled infusion pump or syringe. Administration settings include hospitals, surgical centers, and other clinical environments where sterile IV delivery is ensured.

Serious risks include seizures, peripheral neuropathy, severe allergic reactions such as anaphylaxis, and rare skin conditions like Stevens‑Johnson syndrome. Patients should be monitored for neurological symptoms, rash, or signs of hypersensitivity, and therapy should be discontinued if severe reactions occur.

Patients with known hypersensitivity to metronidazole or other nitroimidazoles should avoid the product. Caution is also advised for individuals with severe hepatic or renal impairment, and those who consume alcohol during therapy due to the risk of a disulfiram‑like reaction.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.