Metronidazol Generis (Metronidazole)

Metronidazole penetrates anaerobic microorganisms and is reduced by intracellular proteins to reactive nitro radicals. These radicals damage DNA and inhibit nucleic acid synthesis, leading to cell death. The reduction is oxygen‑sensitive, so aerobic cells are largely unaffected, providing selective antimicrobial activity.

The dosage of Metronidazol Generis is individualized by the prescribing healthcare professional based on the specific infection, patient age, weight, renal and hepatic function, and other clinical factors. Patients should follow the exact regimen provided by their prescriber.

Safety data for metronidazole in pregnancy are limited, and the product is classified as having an unknown pregnancy category. It should be used only when the potential benefit outweighs any possible risk to the fetus. Breastfeeding mothers should consult their physician, as metronidazole is excreted in breast milk.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials. The sales team then replies with pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Metronidazol Generis belongs to the nitroimidazole class and offers broad activity against anaerobic bacteria and protozoa, often preferred for its oral formulation and cost‑effectiveness. Alternatives such as tinidazole have similar spectra but differ in dosing frequency, while other classes like macrolides lack activity against many anaerobes, making metronidazole a first‑line choice for the listed indications.

Store the product at temperatures below 25 °C, in its original packaging, protected from moisture and direct sunlight. Do not expose the tablets to excessive heat or humidity, and keep them out of reach of children.

Metronidazol Generis is taken orally, usually with food or a full glass of water to reduce gastrointestinal irritation. The tablet should be swallowed whole and not crushed or chewed unless specifically instructed by a healthcare professional.

Serious adverse events, though rare, include seizures, peripheral neuropathy, and severe allergic reactions such as Stevens‑Johnson syndrome or anaphylaxis. Patients should seek immediate medical attention if they experience neurological symptoms, rash, or signs of hypersensitivity.

Metronidazol Generis should be avoided in individuals with a known hypersensitivity to metronidazole or other nitroimidazole compounds. Caution is also advised for patients with severe hepatic or renal impairment, and it should not be used concomitantly with alcohol due to the risk of a disulfiram‑like reaction.