Product image of Metronidazol Hikma (Metronidazole) supplied by GNH India

Metronidazol Hikma

Active Ingredient:
Metronidazole
Origin:
EU

Metronidazol Hikma (Metronidazole)

Metronidazole, the active ingredient in Metronidazol Hikma, is a nitroimidazole presented as an injectable solution for intravenous use. It treats anaerobic bacterial infections and related conditions in adults.

GNH India supplies Metronidazol Hikma as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Hikma Farmacêutica (Portugal), S.A.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Metronidazole is employed to manage infections caused by anaerobic organisms and certain protozoa.

  • Anaerobic bacterial infections: eradicates susceptible anaerobes and resolves infection.
  • Bacterial vaginosis: restores normal vaginal flora by eliminating pathogenic anaerobes.
  • Trichomoniasis: eliminates Trichomonas vaginalis, relieving symptoms.
  • Amebic liver abscess: kills Entamoeba histolytica in hepatic tissue.
  • Clostridioides difficile infection: reduces toxin‑producing bacteria and aids clinical recovery.

How It Works

  • Metronidazole is reduced within anaerobic microorganisms to reactive nitro radicals that interact with DNA, causing strand breakage and inhibition of nucleic acid synthesis. This damage leads to bacterial and protozoal cell death while sparing aerobic cells, providing selective antimicrobial activity against susceptible anaerobes and certain protozoa.

Side Effects

Metronidazole may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Nausea: mild to moderate upset stomach.
  • Metallic taste: transient metallic sensation in the mouth.
  • Headache: occasional dull or throbbing pain.
  • Diarrhea: loose stools during treatment.

Serious or Rare Side Effects

  • Seizures: rare neurologic events requiring immediate care.
  • Peripheral neuropathy: tingling or numbness in extremities.
  • Severe allergic reactions: anaphylaxis or angioedema requiring emergency intervention.

Precautions & Warnings

Metronidazole requires careful use in specific clinical situations.

  • Renal impairment: monitor renal function and adjust therapy as needed.
  • Hepatic dysfunction: use with caution; liver enzymes should be monitored.
  • Alcohol consumption: avoid during and 48 hours after therapy to prevent disulfiram‑like reaction.
  • Pregnancy: safety not established; weigh benefits against potential risks.
  • Concurrent anticoagulants: monitor for increased bleeding tendency.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Metronidazole can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Alcohol: may cause severe disulfiram‑like reaction.
  • Warfarin: increased anticoagulant effect, risk of bleeding.
  • Lithium: heightened lithium toxicity.

Moderate Interactions (Monitor Closely)

  • Phenytoin: may reduce metronidazole plasma levels.
  • Cimetidine: may increase metronidazole concentrations.
  • Theophylline: may raise theophylline levels, risking toxicity.

Frequently Asked Questions

Metronidazol Hikma is indicated for infections caused by anaerobic bacteria and certain protozoa, including anaerobic bacterial infections, bacterial vaginosis, trichomoniasis, amebic liver abscess, and Clostridioides difficile infection. It is administered intravenously under the direction of a qualified prescriber.

Metronidazole enters anaerobic cells and is reduced to reactive nitro radicals. These radicals damage DNA and inhibit nucleic acid synthesis, leading to cell death. The selective activation in low‑oxygen environments provides targeted antimicrobial activity against susceptible anaerobes and protozoa.

The dosage of Metronidazol Hikma is determined by the prescribing clinician based on the specific infection, patient weight, renal and hepatic function, and other clinical factors. Only a qualified health professional should set the dosing regimen.

Safety data for metronidazole in pregnancy are limited, and the product is classified as pregnancy category unknown. It should only be used when the potential benefit justifies any potential risk to the fetus. Breastfeeding mothers should consult their physician, as the drug can be excreted in milk.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Metronidazole is a nitroimidazole that specifically targets anaerobic organisms, offering rapid bactericidal activity. Compared with broad‑spectrum agents like clindamycin, metronidazole often has fewer drug‑interaction concerns and a well‑established efficacy profile for anaerobic and protozoal infections, though choice depends on pathogen susceptibility and patient factors.

Metronidazol Hikma should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the product from moisture, direct sunlight, and extreme temperatures to maintain stability and potency.

Metronidazol Hikma is supplied as an injectable solution for intravenous infusion. Administration is performed by qualified healthcare personnel in a clinical setting, following aseptic technique and the dosing instructions provided by the prescriber.

Serious risks include seizures, peripheral neuropathy, and severe allergic reactions such as anaphylaxis. Patients should be monitored for neurologic symptoms, skin reactions, and any signs of hypersensitivity, and treatment should be discontinued if these events occur.

Metronidazol Hikma is contraindicated in patients with a known hypersensitivity to metronidazole or other nitroimidazole derivatives. Caution is also advised for individuals with severe hepatic impairment, and it should be avoided in patients who have consumed alcohol within 48 hours of dosing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.