Product image of Metronidazol In Viaflo Baxter (Metronidazole) supplied by GNH India

Metronidazol In Viaflo Baxter

Active Ingredient:
Metronidazole
Origin:
EU

Metronidazol In Viaflo Baxter (Metronidazole)

Metronidazole, the active ingredient in Metronidazol In Viaflo Baxter, is a nitroimidazole antibiotic presented as an intravenous solution for intravenous use. It treats anaerobic bacterial infections and certain protozoal infections in hospitalized patients.

GNH India supplies Metronidazol In Viaflo Baxter as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Baxter B.V.

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Indications & Clinical Uses

Metronidazole is used to treat infections caused by anaerobic bacteria and certain protozoa.

  • Anaerobic bacterial infections: effective in eradicating susceptible anaerobic organisms in systemic or localized infections.
  • Trichomoniasis: eliminates the protozoan parasite causing vaginal infection.
  • Bacterial vaginosis: restores normal vaginal flora by targeting anaerobic bacteria.
  • Clostridioides difficile infection: reduces toxin‑producing bacteria in the colon.
  • Intra‑abdominal infections: controls mixed aerobic‑anaerobic infections after surgery or trauma.

How It Works

  • Metronidazole enters susceptible microorganisms and undergoes enzymatic reduction of its nitro group, forming nitro radical anions. These reactive intermediates damage DNA and inhibit nucleic acid synthesis, leading to loss of replication ability and cell death in anaerobic bacteria and certain protozoa.

Side Effects

Metronidazole may cause a range of adverse reactions.

Common Side Effects

  • Nausea: mild to moderate upset stomach.
  • Metallic taste: persistent metallic sensation in the mouth.
  • Headache: occasional mild to moderate headache.
  • Diarrhea: loose stools that may be self‑limiting.
  • Dizziness: transient light‑headedness.
  • Abdominal pain: cramping or discomfort.

Serious or Rare Side Effects

  • Seizures: rare neurologic events requiring immediate care.
  • Peripheral neuropathy: tingling or numbness in extremities.
  • Severe allergic reactions: anaphylaxis, rash, or swelling.
  • Stevens‑Johnson syndrome: severe skin and mucous membrane reaction.
  • Neutropenia: low white‑blood‑cell count increasing infection risk.
  • Hepatic dysfunction: elevated liver enzymes or jaundice.

Precautions & Warnings

Metronidazole requires careful monitoring in several clinical situations.

  • Renal impairment: adjust dosing or monitor plasma levels.
  • Hepatic dysfunction: use with caution; monitor liver function tests.
  • Alcohol consumption: avoid due to disulfiram‑like reaction.
  • Pregnancy: evaluate risk versus benefit; limited data available.
  • Concurrent warfarin therapy: monitor INR closely for enhanced anticoagulation.
  • Store at 2‑8°C: keep refrigerated, protect from light, do not freeze.

Avoid Interactions

Metronidazole can interact with other medicines, affecting safety or efficacy.

Major Interactions (Avoid)

  • Alcohol: may cause severe disulfiram‑like reaction.
  • Lithium: increased risk of lithium toxicity.
  • Warfarin: potentiates anticoagulant effect, raising bleeding risk.

Moderate Interactions (Monitor Closely)

  • Cimetidine: may raise metronidazole plasma concentrations.
  • Phenobarbital: may reduce metronidazole effectiveness.
  • Phenytoin: may decrease metronidazole levels and efficacy.

Frequently Asked Questions

Metronidazol In Viaflo Baxter contains metronidazole, an antibiotic indicated for anaerobic bacterial infections, trichomoniasis, bacterial vaginosis, Clostridioides difficile infection, and intra‑abdominal infections. It is administered intravenously in hospital settings to treat these serious infections.

Metronidazole enters susceptible bacteria and protozoa and is reduced by microbial enzymes to generate nitro radical anions. These reactive species damage DNA and inhibit nucleic acid synthesis, leading to loss of replication ability and cell death in anaerobic organisms.

The specific dose and infusion rate are determined by the prescribing clinician based on the infection type, severity, patient weight, renal and hepatic function, and local treatment guidelines. Dosage should never be altered without medical direction.

Safety data for metronidazole in pregnancy are limited, and the drug is generally used only when the potential benefit outweighs the risk. It is excreted in breast milk, so breastfeeding mothers should consult their healthcare provider before use.

To request Metronidazol In Viaflo Baxter, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and import documentation.

Metronidazole is a nitroimidazole that specifically targets anaerobic bacteria and certain protozoa, offering rapid bactericidal activity. Compared with broad‑spectrum beta‑lactams, it has a narrower spectrum but excellent tissue penetration and is often preferred for mixed anaerobic infections, especially when oral therapy is not feasible.

The product should be stored at 2‑8 °C, protected from light, and kept in its original container. Do not freeze or shake the solution, and use it within the time frame specified on the label after removal from refrigeration.

Metronidazol In Viaflo Baxter is supplied as an intravenous solution. It is administered by slow infusion into a vein under the supervision of qualified healthcare professionals, following aseptic technique and the infusion rate prescribed by the treating physician.

Serious risks include seizures, peripheral neuropathy, severe allergic reactions such as anaphylaxis, Stevens‑Johnson syndrome, neutropenia, and hepatic dysfunction. Patients should be monitored for neurological symptoms, skin reactions, and liver function abnormalities during treatment.

Patients with known hypersensitivity to metronidazole or other nitroimidazoles should avoid the product. Caution is advised in individuals with severe hepatic or renal impairment, those taking interacting medications such as warfarin, lithium, or disulfiram, and pregnant or breastfeeding women unless the benefit justifies the risk.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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