Product image of Metronidazol Serraclinics (Metronidazole) supplied by GNH India

Metronidazol Serraclinics

Active Ingredient:
Metronidazole
Origin:
EU

Metronidazol Serraclinics (Metronidazole)

Metronidazole, the active ingredient in Metronidazol Serraclinics, is a nitroimidazole antibiotic presented as an injectable solution for intravenous use. It treats anaerobic bacterial infections and certain protozoal diseases in adults and children as prescribed.

GNH India supplies Metronidazol Serraclinics as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratorios Serra Pamies S.A.

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Indications & Clinical Uses

Metronidazol Serraclinics is a nitroimidazole antibiotic used to manage infections caused by anaerobic bacteria and selected protozoa.

  • Anaerobic bacterial infections: effective against intra‑abdominal, pelvic and skin‑soft tissue infections caused by anaerobes.
  • Clostridioides difficile infection: helps resolve moderate to severe C. difficile‑associated diarrhea.
  • Bacterial vaginosis: restores normal vaginal flora by eliminating Gardnerella species.
  • Trichomoniasis: eradicates Trichomonas vaginalis in genital infections.
  • Amebic liver abscess: eliminates Entamoeba histolytica in hepatic lesions.

How It Works

  • Metronidazole is taken up by anaerobic microorganisms and reduced to reactive nitro radicals. These radicals damage DNA and inhibit nucleic acid synthesis, leading to loss of replication ability and cell death, while sparing aerobic cells that lack the necessary reduction pathways.

Side Effects

Metronidazol Serraclinics may cause a range of adverse reactions.

Common Side Effects

  • Nausea: mild to moderate upset stomach.
  • Metallic taste: transient metallic sensation in the mouth.
  • Headache: occasional mild to moderate headache.
  • Diarrhea: loose stools during therapy.

Serious or Rare Side Effects

  • Seizures: rare neurologic events requiring immediate attention.
  • Peripheral neuropathy: tingling or numbness in extremities.
  • Severe allergic reactions: anaphylaxis or angioedema.
  • Hepatic dysfunction: elevated liver enzymes or jaundice.

Precautions & Warnings

Before using Metronidazol Serraclinics, consider the following precautions.

  • Pregnancy: Category B – use only if the potential benefit justifies the potential risk to the fetus.
  • Breastfeeding: Caution – drug is excreted in breast milk; assess risk versus benefit.
  • Renal impairment: Monitor renal function; dose adjustment may be required.
  • Alcohol consumption: Avoid concurrent alcohol to prevent a disulfiram‑like reaction.
  • Drug interactions: Review concomitant medications for potential interactions.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Metronidazol Serraclinics can interact with several medicines.

Major Interactions (Avoid)

  • Alcohol: may cause severe flushing, nausea, vomiting, and tachycardia.
  • Warfarin: increased anticoagulant effect, raising bleeding risk.
  • Lithium: heightened lithium toxicity, requiring close monitoring.

Moderate Interactions (Monitor Closely)

  • Cimetidine: may increase metronidazole plasma concentrations.
  • Rifampin: may reduce metronidazole effectiveness by increasing metabolism.

Frequently Asked Questions

Metronidazol Serraclinics is prescribed for anaerobic bacterial infections such as intra‑abdominal and pelvic infections, Clostridioides difficile‑associated diarrhea, bacterial vaginosis, trichomoniasis, and amebic liver abscesses. It is used in both adult and pediatric patients when a nitroimidazole antibiotic is indicated.

Metronidazole enters anaerobic microorganisms and is reduced to nitro radicals. These reactive species damage microbial DNA and inhibit nucleic acid synthesis, leading to cell death while sparing aerobic cells that cannot perform the reduction.

The dosage of Metronidazol Serraclinics is determined by the prescribing clinician based on the specific infection, patient weight, renal function, and severity of disease. The product is supplied as an injectable solution for intravenous administration, and the prescriber sets the exact regimen.

Metronidazol Serraclinics is classified as Pregnancy Category B, indicating that animal studies have not shown risk but there are limited human data. It should be used only if the potential benefit outweighs the risk. The drug is excreted in breast milk, so breastfeeding mothers should discuss risks with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including cold‑chain if needed) and any required import documentation.

Metronidazol Serraclinics shares the same class mechanism as other nitroimidazoles like tinidazole, but it is formulated for intravenous use, offering rapid systemic exposure useful in severe infections. Oral nitroimidazoles are convenient for outpatient therapy, whereas the injectable form is preferred for hospitalized patients requiring immediate drug levels.

The product should be stored at 2‑8 °C in a refrigerator, protected from light. Do not freeze or shake the vial. If temperature excursions occur, discard the solution and obtain a new batch to ensure potency and safety.

Metronidazol Serraclinics is administered intravenously by a qualified healthcare professional. The solution is diluted in an appropriate compatible IV fluid and infused over the time period prescribed by the clinician, typically ranging from 30 minutes to several hours depending on the indication.

Serious adverse events include seizures, peripheral neuropathy, severe allergic reactions such as anaphylaxis, and hepatic dysfunction. Patients should be monitored for neurological symptoms, skin reactions, and liver function abnormalities, and therapy should be discontinued if any of these occur.

Metronidazol Serraclinics is contraindicated in patients with a known hypersensitivity to metronidazole or other nitroimidazole derivatives. It should also be avoided in individuals with severe hepatic impairment or those who cannot abstain from alcohol during therapy due to the risk of a disulfiram‑like reaction.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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