Product image of Metronidazole Bailly-Creat (Metronidazole) supplied by GNH India

Metronidazole Bailly-Creat

Active Ingredient:
Metronidazole
Origin:
EU

Metronidazole Bailly-Creat (Metronidazole)

Metronidazole, the active ingredient in Metronidazole Bailly-Creat, is a nitroimidazole presented as an oral dosage form for oral use. It treats infections caused by anaerobic bacteria and certain protozoa in adults and children as prescribed by a healthcare professional.

GNH India supplies Metronidazole Bailly-Creat as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratoire Bailly-Creat

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Indications & Clinical Uses

  • Metronidazole is an antibiotic that targets anaerobic bacteria and protozoal organisms.
  • Anaerobic bacterial infections: eradicates infection by killing anaerobic bacteria.
  • Bacterial vaginosis: restores normal vaginal flora by eliminating pathogenic anaerobes.
  • Trichomoniasis: treats infection caused by Trichomonas vaginalis.
  • Amebic dysentery: resolves intestinal infection caused by Entamoeba histolytica.

How It Works

  • Metronidazole enters susceptible microorganisms and is reduced by anaerobic electron transport proteins to reactive nitro radicals. These radicals damage DNA, inhibit nucleic acid synthesis, and disrupt essential metabolic pathways, leading to irreversible cell death of anaerobic bacteria and protozoa.

Side Effects

Metronidazole may cause a range of adverse reactions.

Common Side Effects

  • Nausea: mild to moderate upset stomach.
  • Metallic taste: transient metallic sensation in the mouth.
  • Headache: mild to moderate headache.
  • Diarrhoea: loose stools or increased frequency.
  • Abdominal pain: cramping or discomfort.
  • Loss of appetite: reduced desire to eat.

Serious or Rare Side Effects

  • Seizures: convulsions requiring immediate medical attention.
  • Peripheral neuropathy: tingling, numbness, or burning sensations.
  • Severe allergic reactions: rash, swelling, or anaphylaxis.
  • Stevens‑Johnson syndrome: serious skin and mucous membrane disorder.
  • Liver toxicity: elevated liver enzymes or hepatitis.
  • Blood dyscrasias: neutropenia, thrombocytopenia, or aplastic anemia.

Precautions & Warnings

  • Before initiating therapy, consider the following precautions.
  • Assess renal function: adjust use in patients with severe impairment.
  • Avoid alcohol: risk of a disulfiram‑like reaction with flushing and vomiting.
  • Monitor neurological symptoms: report numbness, tingling, or seizures promptly.
  • Use with caution in pregnancy: only if benefits outweigh potential risks.
  • Store at ambient temperature: keep in the original packaging, protect from moisture.

Avoid Interactions

Metronidazole can interact with several medicines; review patient medication lists.

Major Interactions (Avoid)

  • Alcohol: may cause severe nausea, vomiting, and flushing.
  • Warfarin: increased anticoagulant effect, monitor INR closely.
  • Lithium: possible rise in lithium levels, monitor serum concentrations.
  • Cimetidine: may raise metronidazole plasma concentrations.

Moderate Interactions (Monitor Closely)

  • Phenytoin: may reduce metronidazole efficacy.
  • Phenobarbital: may lower metronidazole levels.
  • Carbamazepine: may decrease metronidazole exposure.

Frequently Asked Questions

Metronidazole Bailly-Creat is prescribed to treat anaerobic bacterial infections, bacterial vaginosis, trichomoniasis, and amebic dysentery. It works against organisms that thrive in low‑oxygen environments and certain protozoa, helping to clear the infection when used as directed by a qualified healthcare professional.

Metronidazole is taken up by susceptible microorganisms and reduced by their anaerobic electron‑transport proteins to form nitro radicals. These reactive species damage DNA and inhibit nucleic acid synthesis, ultimately causing cell death of the targeted bacteria or protozoa.

The dosage of Metronidazole Bailly-Creat is determined by the prescribing clinician based on the specific infection, patient age, weight, renal function, and other clinical factors. Patients should follow the exact regimen provided on the prescription label.

Safety in pregnancy and lactation has not been definitively established. The drug should only be used if the potential benefits justify any possible risk to the fetus or infant, and this decision must be made by a qualified healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Metronidazole belongs to the nitroimidazole class and is uniquely effective against obligate anaerobes and certain protozoa. Compared with broad‑spectrum beta‑lactams, it offers targeted activity with a well‑characterised safety profile, making it a first‑line choice for many anaerobic infections when susceptibility is confirmed.

Metronidazole Bailly-Creat should be stored at ambient temperature, below 25 °C, in its original container. Keep the product away from moisture, direct sunlight, and heat sources to maintain its stability and potency.

The medication is administered orally, typically as tablets or capsules, and should be taken with or without food as directed by the prescriber. Swallow the dosage form whole with a full glass of water and complete the full course even if symptoms improve.

Serious adverse events include seizures, peripheral neuropathy, severe allergic reactions such as anaphylaxis, Stevens‑Johnson syndrome, liver toxicity, and blood dyscrasias. Patients should seek immediate medical attention if they experience neurological changes, rash, jaundice, or unusual bleeding.

Individuals with a known hypersensitivity to metronidazole or other nitroimidazole compounds should avoid this medication. Caution is also advised for patients with severe hepatic or renal impairment, and those who are pregnant or breastfeeding should only use it when clearly indicated by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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