Product image of Metronidazole Flamingo Pharma Uk (Metronidazole) supplied by GNH India

Metronidazole Flamingo Pharma Uk

Active Ingredient:
Metronidazole
Origin:
EU

Metronidazole Flamingo Pharma Uk (Metronidazole)

Metronidazole, the active ingredient in Metronidazole Flamingo Pharma Uk, is a nitroimidazole antibiotic presented as an oral dosage form for systemic use. It treats anaerobic bacterial and protozoal infections in adults and children as prescribed.

GNH India supplies Metronidazole Flamingo Pharma Uk as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Flamingo Pharma Uk Ltd

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Indications & Clinical Uses

Metronidazole is a nitroimidazole antibiotic used to manage infections caused by anaerobic bacteria and certain protozoa.

  • Bacterial vaginosis: restores normal vaginal flora by eliminating anaerobic overgrowth.
  • Trichomoniasis: eradicates Trichomonas vaginalis, relieving symptoms and preventing transmission.
  • Amoebiasis: clears intestinal Entamoeba histolytica infection and related liver abscesses.
  • Anaerobic intra‑abdominal infections: controls polymicrobial infections in the abdomen and pelvis.
  • Clostridioides difficile‑associated diarrhea (adjunct): reduces toxin‑producing bacterial load when used with standard therapy.

How It Works

  • Metronidazole enters anaerobic microorganisms and protozoa, where its nitro group is reduced to reactive intermediates. These free radicals interact with DNA, causing strand breaks and loss of helical structure, which inhibits nucleic acid synthesis and leads to cell death. The drug’s selective activation in low‑oxygen environments spares most aerobic host cells.

Side Effects

Metronidazole may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Nausea: mild to moderate upset stomach.
  • Metallic taste: persistent metallic sensation in the mouth.
  • Diarrhea: loose stools during therapy.
  • Abdominal pain: cramping or discomfort.
  • Headache: transient headache episodes.
  • Loss of appetite: reduced desire to eat.

Serious or Rare Side Effects

  • Seizures: rare neurologic events.
  • Peripheral neuropathy: tingling or numbness in extremities.
  • Severe allergic reactions: anaphylaxis or angioedema.
  • Stevens‑Johnson syndrome: severe skin and mucous membrane reaction.
  • Liver toxicity: elevated liver enzymes or hepatitis.
  • Neutropenia: marked reduction in white blood cells.

Precautions & Warnings

Before initiating therapy, consider patient‑specific factors and safety measures.

  • Renal or hepatic impairment: adjust therapy based on function tests.
  • Alcohol avoidance: abstain from alcohol to prevent disulfiram‑like reaction.
  • Pregnancy: use only if clearly needed after risk‑benefit assessment.
  • Neuropathy monitoring: watch for sensory changes during prolonged use.
  • Concomitant medications: review for potential interactions.
  • Store at below 25°C: keep in the original packaging, protect from moisture and heat.

Avoid Interactions

Metronidazole can interact with several medicines, requiring caution.

Major Interactions (Avoid)

  • Alcohol: may cause severe flushing, tachycardia, and nausea.
  • Warfarin: potentiates anticoagulant effect, increasing bleeding risk.
  • Lithium: may raise lithium levels, leading to toxicity.

Moderate Interactions (Monitor Closely)

  • Oral contraceptives: may reduce efficacy, consider backup method.
  • Phenytoin: may alter plasma concentrations of both drugs.
  • Cimetidine: can increase metronidazole levels, watch for toxicity.

Frequently Asked Questions

Metronidazole Flamingo Pharma Uk is prescribed for infections caused by anaerobic bacteria and certain protozoa, including bacterial vaginosis, trichomoniasis, amoebiasis, intra‑abdominal anaerobic infections, and as an adjunct in Clostridioides difficile‑associated diarrhea.

Metronidazole is taken up by anaerobic microorganisms where its nitro group is reduced to reactive radicals. These radicals damage DNA, preventing replication and leading to cell death, which selectively eliminates the targeted pathogens while sparing most aerobic human cells.

The dosage regimen for Metronidazole Flamingo Pharma Uk is determined by the prescribing clinician based on the specific infection, patient age, weight, renal and hepatic function, and other clinical factors. Patients should follow the prescriber’s instructions exactly.

Metronidazole should be used in pregnancy only when clearly needed after a careful risk‑benefit assessment by the healthcare provider. Limited data suggest it may be used in the second and third trimesters, but it is generally avoided in the first trimester. Breastfeeding mothers should consult their physician, as small amounts can pass into milk.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, confirming trade or institutional credentials before providing pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Metronidazole is distinct from many antibiotics because it is activated under anaerobic conditions, making it especially effective against anaerobic bacteria and certain protozoa. Compared with broad‑spectrum agents like clindamycin, it offers a narrower spectrum but fewer risks of Clostridioides difficile overgrowth, though resistance patterns and patient tolerance also influence choice.

Metronidazole Flamingo Pharma Uk should be stored at temperatures below 25 °C, in its original packaging, protected from moisture, direct sunlight and excessive heat. Keeping the product in a dry, cool environment helps maintain its stability and potency throughout its shelf life.

The product is formulated for oral administration. Patients should swallow the tablet whole with a full glass of water, unless directed otherwise by a healthcare professional. It can be taken with or without food, but taking it with meals may reduce gastrointestinal upset.

Serious adverse events, though rare, include seizures, peripheral neuropathy, severe allergic reactions such as anaphylaxis, Stevens‑Johnson syndrome, liver toxicity, and marked neutropenia. Patients should seek immediate medical attention if they experience neurological symptoms, severe skin reactions, or signs of liver dysfunction.

Metronidazole is contraindicated in individuals with a known hypersensitivity to metronidazole or other nitroimidazole compounds. It should also be avoided in patients with severe hepatic impairment or those who are currently consuming alcohol, due to the risk of a disulfiram‑like reaction.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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