Mexalen Baby (Paracetamol)

• Paracetamol is used to manage pain and fever by acting on the central nervous system.
• Fever: reduces elevated body temperature in infants and children.
• Mild to moderate pain: alleviates discomfort from common ailments such as teething or minor injuries.
• Post‑vaccination discomfort: helps lower fever and soreness after immunizations.
• Cold symptoms: eases headache and body aches associated with common colds.

• Paracetamol exerts its effect primarily by inhibiting cyclooxygenase (COX) enzymes in the central nervous system, particularly COX‑2, which leads to decreased synthesis of prostaglandins involved in pain signaling and thermoregulation. The peripheral anti‑inflammatory activity is minimal, allowing effective antipyretic and analgesic action without significant anti‑inflammatory effects. This central inhibition reduces the perception of pain and lowers the hypothalamic set‑point for body temperature.

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

• Nausea: mild stomach upset that usually resolves without treatment.
• Skin rash: occasional mild erythema or itching.
• Elevated liver enzymes: transient increase detectable in blood tests.

Serious or Rare Side Effects

• Severe allergic reaction (anaphylaxis): difficulty breathing, swelling of face or throat.
• Stevens‑Johnson syndrome: severe skin blistering and mucosal involvement.
• Hepatotoxicity: potential liver injury with overdose or prolonged use.

• When using Mexalen Baby, consider the following precautions to ensure safe administration.
• Age limitation: Use only in children as directed by a healthcare professional; avoid use in infants under 2 months unless advised.
• Dosage accuracy: Measure each dose with the provided calibrated device to prevent dosing errors.
• Liver function: Avoid use in patients with known severe liver disease or impaired hepatic function.
• Concomitant medications: Do not combine with other paracetamol‑containing products to prevent overdose.
• Allergies: Discontinue if signs of hypersensitivity such as rash, swelling, or breathing difficulty appear.
• Store at ambient temperature: Store below 25°C: keep in the original pack, protect from moisture.

Paracetamol may interact with certain medicines; awareness of these interactions helps minimize risk.

Major Interactions (Avoid)

• Warfarin: concurrent use may increase bleeding risk; monitor INR closely.
• Carbamazepine: enzyme induction can reduce paracetamol efficacy.

Moderate Interactions (Monitor Closely)

• Isoniazid: may increase risk of liver toxicity; assess liver function.
• Alcohol: chronic intake can enhance hepatotoxic potential.
• Phenytoin: may lower paracetamol plasma levels.