Product image of Mexalen (Paracetamol) supplied by GNH India

Mexalen

Active Ingredient:
Paracetamol
Origin:
EU

Mexalen (Paracetamol)

Paracetamol, the active ingredient in Mexalen, is an analgesic presented as an oral tablet for oral use. It reduces fever and relieves mild to moderate pain in adults and children.
GNH India supplies Mexalen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

  • Paracetamol acts as an antipyretic and analgesic, addressing common pain and fever pathways.
  • Fever: lowers elevated body temperature to normal levels.
  • Headache: alleviates tension‑type and mild migraine pain.
  • Musculoskeletal pain: reduces discomfort from strains, sprains and minor injuries.
  • Dental pain: eases pain associated with toothaches and dental procedures.
  • Menstrual discomfort: helps relieve mild dysmenorrhea.

How It Works

  • Paracetamol inhibits cyclooxygenase enzymes, primarily COX‑2, within the central nervous system, leading to decreased synthesis of prostaglandins that mediate pain and fever. This central action provides antipyretic and analgesic effects without significant peripheral anti‑inflammatory activity.

Side Effects

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea or stomach upset
  • Mild abdominal discomfort
  • Transient headache
  • Dizziness or light‑headedness
  • Skin rash or mild itching
  • Sweating or flushing

Serious or Rare Side Effects

  • Severe skin reactions such as Stevens‑Johnson syndrome
  • Hepatotoxicity, especially with overdose or chronic use
  • Blood disorders including thrombocytopenia
  • Anaphylactic or severe allergic reactions
  • Acute renal failure in susceptible individuals
  • Hypersensitivity with angioedema

Precautions & Warnings

Paracetamol should be used with awareness of safety considerations.

  • Dose limitation: do not exceed the maximum daily amount recommended by a healthcare professional.
  • Alcohol avoidance: limit alcohol intake to reduce liver stress.
  • Liver monitoring: assess hepatic function in patients with existing liver disease.
  • Hypersensitivity: discontinue use if rash, swelling or breathing difficulty develop.
  • Pregnancy and breastfeeding: consult a physician before use.
  • Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Paracetamol may interact with several medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Warfarin: increased risk of bleeding.
  • Carbamazepine: reduced analgesic effect.
  • Isoniazid: heightened potential for liver toxicity.
  • Alcohol: synergistic hepatotoxicity.

Moderate Interactions (Monitor Closely)

  • Oral contraceptives: possible reduction in contraceptive efficacy.
  • Phenytoin: may lower paracetamol plasma levels.
  • HIV protease inhibitors: altered metabolism increasing exposure.
  • Fluconazole: may increase paracetamol concentrations.

Frequently Asked Questions

Mexelen contains paracetamol, which is used to reduce fever and relieve mild to moderate pain such as headaches, toothaches, musculoskeletal discomfort, and menstrual cramps. It is an over‑the‑counter option for temporary symptom relief in adults and children.

Paracetamol works by inhibiting cyclooxygenase enzymes in the central nervous system, which reduces the production of prostaglandins that trigger pain and raise body temperature. This central action provides antipyretic and analgesic effects without significant anti‑inflammatory activity.

The appropriate dose of Mexelen is determined by a prescriber based on the patient’s age, weight, clinical condition, and local guidelines. Patients should follow the healthcare professional’s instructions and never exceed the recommended maximum daily amount.

Paracetamol is generally considered safe for short‑term use during pregnancy and breastfeeding when prescribed by a healthcare professional. However, pregnant or nursing individuals should consult their doctor before taking Mexelen to ensure it is appropriate for their specific situation.

To order Mexelen, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with non‑steroidal anti‑inflammatory drugs (NSAIDs), paracetamol offers effective fever reduction and pain relief with a lower risk of gastrointestinal irritation and platelet inhibition. It lacks the anti‑inflammatory properties of NSAIDs, making it suitable for patients who cannot tolerate those agents.

Mexelen should be stored below 25 °C in a dry place, kept in its original packaging, and protected from moisture and direct sunlight. Ensure the container is tightly closed to maintain product stability throughout its shelf life.

Mexelen is taken orally, usually with a glass of water. The tablet should be swallowed whole and not crushed or chewed unless the formulation specifically allows it. Follow the dosing instructions provided by a healthcare professional.

The most serious risks include severe liver injury, especially with overdose or chronic high‑dose use, and rare but serious skin reactions such as Stevens‑Johnson syndrome. Prompt medical attention is required if signs of liver dysfunction or severe skin changes appear.

Individuals with known hypersensitivity to paracetamol or any excipients in the tablet should avoid Mexelen. Patients with severe liver disease, chronic alcohol misuse, or those taking interacting medications such as warfarin should consult a physician before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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