Product image of Mexaratio (Paracetamol) supplied by GNH India

Mexaratio

Active Ingredient:
Paracetamol
Origin:
EU

Mexaratio (Paracetamol)

Paracetamol, the active ingredient in Mexaratio, is an analgesic presented as an oral tablet for oral use. It reduces pain and fever and is commonly used in adults and children for mild to moderate discomfort.

GNH India supplies Mexaratio as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable sourcing for regulated markets. Mexaratio is manufactured under EU GMP guidelines and undergoes comprehensive testing to ensure purity and potency.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

  • Paracetamol acts as an analgesic and antipyretic, relieving pain and reducing fever.
  • Pain: alleviates mild to moderate pain such as headache, toothache, or muscle aches.
  • Fever: reduces elevated body temperature in febrile illnesses.
  • Cold symptoms: eases discomfort associated with common cold and flu.

How It Works

  • Paracetamol exerts its effect primarily by inhibiting cyclooxygenase (COX) enzymes in the central nervous system, particularly COX‑2, which leads to decreased synthesis of prostaglandins involved in pain signaling and thermoregulation. The peripheral COX inhibition is weak, accounting for its limited anti‑inflammatory activity. It also modulates serotonergic pathways that contribute to analgesia and may affect the hypothalamic heat‑regulation center, further supporting its antipyretic action.

Side Effects

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea: mild stomach upset may occur.
  • Skin rash: transient erythema or itching.
  • Headache: occasional mild headache.
  • Elevated liver enzymes: mild, reversible increase in liver function tests.

Serious or Rare Side Effects

  • Hepatotoxicity: severe liver injury, especially with overdose.
  • Stevens‑Johnson syndrome: rare severe skin reaction.
  • Blood disorders: agranulocytosis or thrombocytopenia.
  • Anaphylaxis: rare allergic reaction with breathing difficulty.

Precautions & Warnings

  • When using Mexaratio, consider the following precautions.
  • Dosage adjustment: reduce dose in patients with hepatic impairment.
  • Alcohol use: avoid excessive alcohol while taking.
  • Age restrictions: use with caution in children under 2 years.
  • Drug interactions: review concomitant medications for potential interactions.
  • Pregnancy and lactation: safety not established; consult healthcare professional.
  • Store at below 25°C: keep in original packaging, protect from moisture.

Avoid Interactions

Paracetamol may interact with several medicines, altering its efficacy or safety.

Major Interactions (Avoid)

  • Warfarin: increased anticoagulant effect, monitor INR.
  • Rifampicin: may reduce paracetamol plasma levels.
  • High-dose alcohol: heightened risk of liver toxicity.

Moderate Interactions (Monitor Closely)

  • Carbamazepine: may increase metabolism, reduce effect.
  • Phenobarbital: may lower plasma concentration.
  • Isoniazid: may increase risk of hepatotoxicity.

Frequently Asked Questions

Mexaratio contains paracetamol and is used as an over‑the‑counter analgesic and antipyretic. It helps relieve mild to moderate pain such as headaches, toothaches, muscle aches, and it lowers elevated body temperature associated with fever.

Paracetamol works by inhibiting cyclooxygenase enzymes in the central nervous system, which reduces the production of prostaglandins that signal pain and regulate body temperature. This central action provides pain relief and fever reduction while having minimal peripheral anti‑inflammatory effect.

The appropriate dose of Mexaratio is determined by a qualified prescriber based on the patient’s age, weight, clinical condition, and local guidelines. Adults typically receive a standard adult dose, while pediatric dosing follows weight‑based recommendations, but exact amounts should always be confirmed by a healthcare professional.

Safety data for paracetamol in pregnancy and lactation are limited for this specific product. Healthcare providers generally weigh potential benefits against risks. Women who are pregnant or breastfeeding should consult their physician before using Mexaratio to ensure it is appropriate for their situation.

To order Mexaratio, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Both Mexaratio (paracetamol) and ibuprofen relieve pain and fever, but they belong to different classes. Paracetamol has minimal anti‑inflammatory activity and a lower risk of gastrointestinal irritation, while ibuprofen provides stronger anti‑inflammatory effects but may affect stomach lining and kidney function. Choice depends on the clinical need and patient tolerance.

Mexaratio should be stored at temperatures below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability throughout its shelf life.

Mexaratio is administered orally. The tablet should be swallowed whole with a glass of water. It can be taken with or without food, but patients should follow the dosing instructions provided by their healthcare professional.

The most serious risks include severe liver injury (hepatotoxicity), especially with overdose or chronic high‑dose use, and rare severe skin reactions such as Stevens‑Johnson syndrome. Prompt medical attention is required if signs of liver dysfunction or serious skin changes occur.

Individuals with known hypersensitivity to paracetamol or any excipients in the tablet should avoid Mexaratio. Patients with severe liver disease, those who consume excessive alcohol, and children under the age recommended by local guidelines should not use this product without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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