Product image of Mexilon (Meloxicam) supplied by GNH India

Mexilon

Active Ingredient:
Meloxicam
Origin:
EU

Mexilon (Meloxicam)

Meloxicam, the active ingredient in Mexilon, is a nonsteroidal anti-inflammatory drug presented as an injectable solution for intramuscular use. It treats pain and inflammation associated with osteoarthritis, rheumatoid arthritis and other musculoskeletal conditions in adults.

GNH India supplies Mexilon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Medicus A.E

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Indications & Clinical Uses

Meloxicam is an NSAID used to manage inflammatory and painful conditions affecting the musculoskeletal system.

  • Osteoarthritis: reduces joint pain and improves functional mobility.
  • Rheumatoid arthritis: decreases synovial inflammation and limits disease‑related damage.
  • Acute pain: provides rapid analgesia for postoperative or injury‑related pain.

How It Works

  • Meloxicam selectively inhibits cyclooxygenase‑2 (COX‑2) enzymes, with lesser effect on COX‑1, leading to reduced synthesis of prostaglandins that mediate inflammation, pain, and fever. By limiting prostaglandin production at sites of tissue injury, it diminishes the inflammatory response and associated discomfort.

Side Effects

Adverse reactions may range from mild to severe and should be monitored during therapy.

Common Side Effects

  • Gastrointestinal upset (nausea, dyspepsia)
  • Headache
  • Dizziness
  • Injection‑site pain or erythema
  • Mild skin rash
  • Elevated liver enzymes

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding
  • Severe cutaneous reactions (e.g., Stevens‑Johnson syndrome)
  • Acute renal impairment or failure
  • Cardiovascular events such as myocardial infarction
  • Anaphylactic or anaphylactoid reactions
  • Hepatic failure or severe hepatitis

Precautions & Warnings

When prescribing meloxicam, clinicians should consider several safety measures.

  • Renal function assessment: evaluate baseline kidney status before initiation.
  • Hepatic monitoring: check liver enzymes periodically during treatment.
  • Dose minimisation: use the lowest effective dose for the shortest duration needed.
  • Hypersensitivity avoidance: discontinue if signs of allergic reaction appear.
  • Concomitant anticoagulant caution: monitor bleeding risk when combined with warfarin or similar agents.
  • Store at 2‑8°C: keep refrigerated, protect from light, do not freeze or shake the vial.

Avoid Interactions

Meloxicam can interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs or aspirin: heightened gastrointestinal toxicity.
  • ACE inhibitors or ARBs: may reduce renal function, especially in dehydrated patients.

Moderate Interactions (Monitor Closely)

  • Lithium: meloxicam may raise lithium serum levels, requiring dose adjustment.
  • Methotrexate: potential for enhanced methotrexate toxicity; monitor blood counts and liver function.

Frequently Asked Questions

Mexilon, containing meloxicam, is indicated for the relief of pain and reduction of inflammation in conditions such as osteoarthritis, rheumatoid arthritis, and acute musculoskeletal pain following surgery or injury. It is administered by intramuscular injection and is prescribed for adult patients requiring anti‑inflammatory therapy.

Meloxicam works by selectively inhibiting the cyclooxygenase‑2 (COX‑2) enzyme, which reduces the production of prostaglandins—chemical mediators that cause inflammation, pain, and fever. By lowering prostaglandin levels at sites of tissue injury, meloxicam diminishes the inflammatory response and associated discomfort.

The dosage of Mexilon is determined by the prescribing healthcare professional based on the patient’s clinical condition, severity of symptoms, and individual risk factors. The prescriber will select the appropriate amount and frequency according to current medical guidelines and the patient’s response to therapy.

The safety of meloxicam during pregnancy and lactation has not been established, and the product’s pregnancy category is listed as unknown. It should be used only if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To request Mexilon, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including any cold‑chain requirements), and the necessary import documentation.

Mexilon (meloxicam) offers a longer half‑life and greater COX‑2 selectivity compared with many traditional NSAIDs such as ibuprofen or diclofenac. This can allow once‑daily dosing and may reduce gastrointestinal side effects, although individual tolerance varies. Clinicians choose meloxicam when a sustained anti‑inflammatory effect is desired with a potentially lower risk of gastric irritation.

Mexilon should be stored at 2‑8 °C (refrigerated). Keep the vials in their original packaging, protect them from light, and avoid freezing or shaking. If the product must be transported, maintain the cold‑chain to preserve stability and potency.

Mexilon is supplied as an injectable solution for intramuscular (IM) administration. A qualified healthcare professional injects the prescribed dose into a suitable muscle, typically the gluteal or deltoid region, following aseptic technique. The injection site should be monitored for local reactions after administration.

Serious risks include gastrointestinal ulceration or bleeding, severe skin reactions such as Stevens‑Johnson syndrome, acute renal impairment, cardiovascular events like myocardial infarction, and anaphylactic reactions. Patients should be educated to seek immediate medical attention if they experience symptoms such as severe abdominal pain, rash, swelling, difficulty breathing, or sudden loss of kidney function.

Mexilon is contraindicated in patients with known hypersensitivity to meloxicam or any other NSAIDs, those with active gastrointestinal bleeding or ulceration, and individuals with severe renal or hepatic impairment. It should also be avoided in patients who have experienced a previous severe cardiovascular event related to NSAID use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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