Product image of Mexolan (Meloxicam) supplied by GNH India

Mexolan

Active Ingredient:
Meloxicam
Origin:
EU

Mexolan (Meloxicam)

Meloxicam, the active ingredient in Mexolan, is a nonsteroidal anti-inflammatory drug presented as a injectable solution for intramuscular use. It treats pain and inflammation associated with osteoarthritis, rheumatoid arthritis and other musculoskeletal conditions.

GNH India supplies Mexolan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

G.L. Pharma Gmbh

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Indications & Clinical Uses

Meloxicam is used to manage pain and inflammation in musculoskeletal disorders.

  • Osteoarthritis: reduces joint pain and improves mobility.
  • Rheumatoid arthritis: alleviates inflammatory joint symptoms.
  • Acute pain: provides short‑term relief of moderate to severe pain.
  • Post‑operative pain: helps control pain after surgical procedures.

How It Works

  • Meloxicam selectively inhibits the cyclooxygenase‑2 (COX‑2) enzyme, which reduces the synthesis of prostaglandins that mediate inflammation, pain, and fever. By sparing COX‑1 activity, it aims to maintain gastric mucosal protection while delivering anti‑inflammatory and analgesic effects.

Side Effects

Meloxicam may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness: feeling of light‑headedness or unsteadiness.
  • Injection site reactions: erythema, swelling or pain at the intramuscular site.

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding: serious stomach or intestinal lesions.
  • Cardiovascular events: increased risk of heart attack or stroke.
  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.

Precautions & Warnings

Before using Mexolan, consider the following precautions to minimize risks.

  • Renal function: assess kidney status, especially in patients with existing impairment.
  • Cardiovascular risk: avoid in individuals with recent myocardial infarction or uncontrolled hypertension.
  • Gastrointestinal history: use cautiously in patients with ulcer disease or bleeding.
  • Concomitant anticoagulants: monitor for increased bleeding tendency.
  • Pregnancy and lactation: avoid use unless clearly needed, as safety is not established.
  • Store at ambient temperature: keep below 25°C, protect from moisture and light, retain in original packaging.

Avoid Interactions

Meloxicam can interact with several medicines; awareness of these interactions helps ensure safe therapy.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): may increase bleeding risk.
  • Other NSAIDs or COX‑2 inhibitors: heightened gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): elevated chance of bleeding.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal function.
  • Diuretics: potential for decreased kidney perfusion.
  • Lithium: NSAIDs can raise lithium serum levels.
  • Methotrexate: reduced clearance may increase toxicity.

Frequently Asked Questions

Mexolan is an injectable formulation of meloxicam indicated for the relief of pain and inflammation associated with osteoarthritis, rheumatoid arthritis, acute musculoskeletal pain, and postoperative discomfort. It is prescribed when a rapid, systemic anti‑inflammatory effect is required.

Meloxicam works by selectively blocking the cyclooxygenase‑2 (COX‑2) enzyme, which reduces the production of prostaglandins—chemical mediators that cause inflammation, pain, and fever. This selective inhibition helps control symptoms while preserving COX‑1 activity that protects the stomach lining.

The exact dose of Mexolan is determined by the prescribing clinician based on the patient’s condition, weight, renal function, and response to therapy. Healthcare professionals adjust the amount and frequency to achieve optimal pain control while minimizing risk.

Safety of meloxicam in pregnancy and lactation has not been established. It is generally avoided unless the potential benefit justifies the potential risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternatives with their healthcare provider.

To order Mexolan, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and necessary import documentation.

Compared with non‑selective NSAIDs, meloxicam offers greater COX‑2 selectivity, which may lower the incidence of gastrointestinal irritation while still providing strong anti‑inflammatory and analgesic effects. However, cardiovascular and renal risks remain similar to other NSAIDs, so patient‑specific factors guide drug choice.

Mexolan should be stored at ambient temperature, below 25 °C, in its original container to protect it from moisture and light. Do not freeze the product. Keep it out of reach of children and handle using standard aseptic techniques for injectable medicines.

Mexolan is given by intramuscular injection, typically into a large muscle such as the gluteus maximus. The injection should be performed by a qualified healthcare professional using aseptic technique, and the dose is administered according to the prescriber’s instructions.

Serious risks include gastrointestinal ulceration or bleeding, cardiovascular events such as heart attack or stroke, and severe skin reactions like Stevens‑Johnson syndrome. Patients should be monitored for signs of abdominal pain, chest discomfort, sudden weakness, or rash, and seek immediate medical attention if these occur.

Mexolan is contraindicated in patients with known hypersensitivity to meloxicam or other NSAIDs, those with active gastrointestinal bleeding or ulceration, severe heart failure, and in the third trimester of pregnancy. Caution is also advised for individuals with impaired renal or hepatic function.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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