Mezatil Sr (Diltiazem Hydrochloride)

Diltiazem blocks L‑type calcium channels in the heart and vascular smooth muscle. By reducing calcium entry, it decreases the force of heart muscle contraction, slows electrical conduction through the atrioventricular node, and causes peripheral vasodilation, collectively lowering blood pressure and reducing myocardial oxygen demand.

The specific dose of Mezatil Sr is determined by the prescribing clinician based on the individual’s medical condition, response to therapy, and other factors. Healthcare professionals adjust the regimen to achieve optimal blood pressure control, angina relief, or heart‑rate management.

Safety data for diltiazem in pregnancy and lactation are limited, and the product is classified as having an unknown pregnancy category. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To request Mezatil Sr, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Diltiazem, the active ingredient in Mezatil Sr, has a balanced profile of cardiac and vascular effects, offering both heart‑rate control and vasodilation. Compared with pure vascular agents like amlodipine, diltiazem provides more pronounced AV‑node slowing, making it useful for atrial fibrillation, while still effectively treating hypertension and angina.

Mezatil Sr should be stored at room temperature, below 25 °C, in its original packaging. Protect the product from moisture, excessive heat and direct sunlight to maintain its stability and potency throughout its shelf life.

Mezatil Sr is taken orally, usually with or without food, as directed by a healthcare professional. The tablet should be swallowed whole with a glass of water and not chewed or crushed unless specifically advised by the prescriber.

Serious adverse events, though uncommon, include severe bradycardia, heart block, marked hypotension, hepatic dysfunction, allergic reactions such as rash or angioedema, and, in rare cases, myocardial infarction. Patients should seek immediate medical attention if they experience symptoms like fainting, rapid weight gain, jaundice or severe chest pain.

Mezatil Sr is contraindicated in individuals with known hypersensitivity to diltiazem or any component of the formulation, those with severe sinus node dysfunction, second‑ or third‑degree AV block without a pacemaker, and patients with cardiogenic shock or acute myocardial infarction unless specifically directed by a cardiologist.