Product image of Mgd Direct 400 Mg Lt (Magnesium Oxide, Heavy, Magnesium Citrate Dibasic) supplied by GNH India

Mgd Direct 400 Mg Lt

Active Ingredient:
Magnesium Oxide, Heavy, Magnesium Citrate Dibasic
Origin:
EU

Mgd Direct 400 Mg Lt (Magnesium Oxide, Heavy, Magnesium Citrate Dibasic)

Magnesium, the active ingredient in Mgd Direct 400 Mg Lt, is a magnesium supplement presented as a 400 mg oral tablet for oral use. It treats magnesium deficiency, hypomagnesemia and muscle cramps in adults.

GNH India supplies Mgd Direct 400 Mg Lt as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to strict quality standards and provides reliable logistics for global distribution. All batches are manufactured under EU GMP guidelines and undergo rigorous testing before release.

Manufacturer / TM Owner

Protina Pharmazeutische Gesellschaft Mbh

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Indications & Clinical Uses

Mgd Direct 400 Mg Lt, a magnesium supplement, supports electrolyte balance and neuromuscular function in conditions related to low magnesium levels.

  • Magnesium deficiency: helps restore normal serum magnesium concentrations, supporting overall metabolic health.
  • Hypomagnesemia: contributes to correction of clinically low magnesium levels, aiding cardiac and nerve stability.
  • Muscle cramps: may reduce frequency and intensity of involuntary muscle contractions, improving comfort during daily activities.
  • Bone health support: supplies magnesium that contributes to bone mineral density and structural integrity.

How It Works

  • After oral ingestion, the magnesium salts dissociate into Mg2+ ions that are absorbed in the intestine. These ions serve as essential cofactors for hundreds of enzymatic reactions, including ATP synthesis, protein and nucleic acid formation, and regulation of ion channels. By stabilizing cell membranes and modulating calcium transport, magnesium influences nerve impulse transmission, muscle contraction and cardiac electrophysiology, thereby maintaining normal muscular, neural and cardiac function.

Side Effects

Oral magnesium supplementation can be associated with a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Diarrhea: loose stools due to osmotic effect.
  • Abdominal discomfort: cramping or pain in the stomach area.
  • Nausea: feeling of queasiness.

Serious or Rare Side Effects

  • Hypermagnesemia: elevated serum magnesium causing lethargy, hypotension, or cardiac arrhythmia.
  • Allergic reaction: rash, itching, swelling, or anaphylaxis.
  • Respiratory depression: slowed breathing in severe cases.

Precautions & Warnings

When using Mgd Direct 400 Mg Lt, certain precautions should be observed to ensure safety and effectiveness.

  • Renal impairment: monitor serum magnesium levels and adjust use as needed.
  • Cardiac disease: use cautiously in patients with conduction abnormalities.
  • Concomitant medications: review for potential interactions before initiating therapy.
  • Pregnancy and lactation: consult a healthcare professional prior to use.
  • Store at ambient temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Magnesium can interact with several medicines, affecting absorption or physiological effects.

Major Interactions (Avoid)

  • Calcium channel blockers: may increase risk of hypermagnesemia.
  • Aminoglycoside antibiotics: magnesium can reduce their efficacy.
  • Bisphosphonates: concurrent use decreases absorption of both agents.

Moderate Interactions (Monitor Closely)

  • Loop and thiazide diuretics: may alter magnesium balance.
  • Proton pump inhibitors: long‑term use can affect magnesium status.
  • Oral iron supplements: magnesium may reduce iron absorption when taken together.

Frequently Asked Questions

Mgd Direct 400 Mg Lt is an oral magnesium supplement used to correct magnesium deficiency, treat hypomagnesemia, and help alleviate muscle cramps by providing bioavailable magnesium ions that support normal neuromuscular and cardiac function.

Magnesium acts as a cofactor for more than 300 enzymatic reactions, including those involved in ATP production, protein synthesis, and nucleic acid metabolism. It also stabilizes cell membranes, regulates calcium channels, and modulates nerve impulse transmission, muscle contraction and heart rhythm.

The appropriate dose is determined by a qualified healthcare professional based on the individual’s clinical condition, laboratory values and overall health status. Patients should follow the prescriber’s instructions and not adjust the dose without medical advice.

Safety in pregnancy and lactation has not been definitively established. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential benefits and risks with their healthcare provider before using the product.

Enquiries are submitted via the product page on gnhindia.com, where you specify the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Mgd Direct 400 Mg Lt combines magnesium oxide and magnesium citrate dibasic, offering both elemental magnesium and good oral bioavailability. Compared with single‑salt products, this blend may provide a balance of high elemental content and improved absorption, though individual response can vary.

Store the tablets at ambient temperature, preferably below 25 °C, in the original container to protect them from moisture and direct sunlight. Keep out of reach of children and do not use after the expiry date printed on the packaging.

The product is taken orally, usually with a full glass of water. It may be taken with or without food, but if gastrointestinal upset occurs, it can be taken with meals. Follow the dosing instructions provided by your prescriber.

The most serious risks include hypermagnesemia, which can cause lethargy, hypotension, cardiac arrhythmias, and in extreme cases respiratory depression. Allergic reactions such as rash, swelling or anaphylaxis are also possible and require immediate medical attention.

Individuals with severe renal impairment, known hypersensitivity to magnesium salts, or those taking medications that may cause dangerous magnesium accumulation should avoid this product unless directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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