Product image of Miansec (Mianserin Hydrochloride) supplied by GNH India

Miansec

Active Ingredient:
Mianserin Hydrochloride
Origin:
EU

Miansec (Mianserin Hydrochloride)

Mianserin Hydrochloride, the active ingredient in Miansec, is a tetracyclic antidepressant presented as an oral tablet for oral use. It is indicated for the treatment of major depressive disorder in adult patients.

GNH India supplies Miansec as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Pharmaswiss Česká Republika S.R.O.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Mianserin is a tetracyclic antidepressant that modulates noradrenergic and serotonergic pathways in depressive disorders.

  • Major depressive disorder: reduces depressive symptoms and improves mood.
  • Depressive episodes in bipolar disorder: helps stabilize depressive phases.
  • Anxiety associated with depression: alleviates concurrent anxiety symptoms.

How It Works

  • Mianserin acts as an antagonist at central presynaptic α2‑adrenergic receptors and several serotonin receptors (5‑HT2, 5‑HT3), while also displaying antihistaminic activity. By blocking α2 receptors it enhances noradrenergic release, and serotonin receptor antagonism increases serotonergic neurotransmission, collectively contributing to its antidepressant effect.

Side Effects

Mianserin may cause a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Drowsiness: feeling unusually sleepy or fatigued.
  • Dry mouth: reduced salivation causing throat discomfort.
  • Weight gain: increase in body weight over time.
  • Constipation: difficulty passing stools.

Serious or Rare Side Effects

  • Agranulocytosis: severe reduction in white blood cells.
  • Seizures: occurrence of convulsive episodes.
  • Cardiac arrhythmia: irregular heart rhythm that may be life‑threatening.

Precautions & Warnings

Before initiating therapy, clinicians should consider several safety measures.

  • Monitor blood pressure: watch for hypotensive episodes.
  • Assess hepatic function: evaluate liver enzymes periodically.
  • Evaluate suicidal ideation: screen patients for worsening mood.
  • Use caution in the elderly: increased sensitivity to sedative effects.
  • Avoid abrupt discontinuation: taper gradually to reduce withdrawal.
  • Store at room temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Mianserin can interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors: risk of hypertensive crisis.
  • Selective serotonin reuptake inhibitors: potential serotonin syndrome.
  • CNS depressants: enhanced sedation and respiratory depression.

Moderate Interactions (Monitor Closely)

  • Antihistamines: additive drowsiness.
  • Antihypertensives: possible additive hypotensive effect.

Frequently Asked Questions

Miansec contains Mianserin Hydrochloride, which is prescribed for the treatment of major depressive disorder in adults. It helps alleviate depressive symptoms by modulating noradrenergic and serotonergic neurotransmission.

Mianserin blocks central presynaptic α2‑adrenergic receptors and several serotonin receptors (5‑HT2, 5‑HT3), while also acting as an antihistamine. This combination increases the release of norepinephrine and serotonin, improving mood and reducing depressive symptoms.

The appropriate dose of Miansec is determined by the prescribing clinician based on the patient’s condition, response, and tolerability. Dosage adjustments are made individually and should follow the prescriber’s instructions.

Safety data for Mianserin Hydrochloride in pregnancy and lactation are limited. Healthcare providers should weigh potential benefits against risks and consider alternative therapies when treating pregnant or nursing individuals.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and necessary import documentation.

Mianserin is a tetracyclic antidepressant, differing from SSRIs and SNRIs in its receptor profile. It offers strong antihistaminic and sedative properties, which can be advantageous for patients with insomnia, but may cause more sedation compared with newer agents.

Miansec should be stored at room temperature, below 25 °C, in its original packaging. Keep the product away from moisture and direct sunlight to maintain stability.

Miansec is taken orally, usually as a tablet, with or without food as directed by the prescriber. Swallow the tablet whole with a glass of water and follow the dosing schedule provided by the healthcare professional.

Serious risks include agranulocytosis, seizures, and cardiac arrhythmias. Patients should be monitored for signs of infection, neurological changes, or heart rhythm disturbances, and any concerning symptoms should prompt immediate medical evaluation.

Miansec is contraindicated in individuals with known hypersensitivity to Mianserin or any of its excipients, and in patients currently taking monoamine oxidase inhibitors. Caution is also advised for those with severe hepatic impairment or uncontrolled cardiovascular disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Mianserin Hydrochloride

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT