Product image of Micafungin Olikla (Micafungin) supplied by GNH India

Micafungin Olikla

Active Ingredient:
Micafungin
Origin:
EU

Micafungin Olikla (Micafungin)

Micafungin, the active ingredient in Micafungin Olikla, is an echinocandin presented as an intravenous solution for intravenous use. It treats invasive Candida infections and is used for prophylaxis in high‑risk patients such as those undergoing hematopoietic stem cell transplantation.

GNH India supplies Micafungin Olikla as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Olikla S.R.O.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Micafungin is an echinocandin antifungal used to manage serious Candida infections and to prevent infection in high‑risk patients.

  • Invasive candidiasis: clears bloodstream and deep‑tissue Candida infections.
  • Esophageal candidiasis: resolves fungal infection of the esophagus.
  • Prophylaxis of Candida infections in patients undergoing hematopoietic stem cell transplantation: prevents invasive disease.
  • Candida peritonitis and intra‑abdominal infections: treats these severe intra‑abdominal fungal infections.

How It Works

  • Micafungin inhibits the enzyme β‑(1,3)‑D‑glucan synthase, which is essential for synthesizing β‑(1,3)‑D‑glucan, a critical component of the fungal cell wall. By blocking this pathway, the drug weakens the cell wall, leading to osmotic instability and fungal cell lysis without affecting human cells.

Side Effects

Micafungin may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Fever: transient elevation of body temperature.
  • Nausea: mild to moderate upset stomach.
  • Headache: occasional mild headache.
  • Infusion‑related reactions: flushing, chills, or erythema.
  • Elevated liver enzymes: mild transaminase increase.
  • Rash: mild skin irritation.

Serious or Rare Side Effects

  • Hepatic failure: significant liver dysfunction.
  • Severe hypersensitivity: anaphylactic reactions.
  • Stevens‑Johnson syndrome: severe skin and mucosal involvement.
  • Renal failure: impaired kidney function.
  • Severe neutropenia: marked reduction in neutrophil count.
  • Cardiovascular collapse: rare hypotensive events.

Precautions & Warnings

When using Micafungin, clinicians should consider several safety measures.

  • Renal impairment: adjust therapy and monitor kidney function.
  • Hepatic impairment: assess liver enzymes before and during treatment.
  • Concomitant hepatotoxic drugs: avoid or monitor for additive liver injury.
  • Pregnancy and lactation: safety not established; weigh benefits against risks.
  • Pediatric use: not approved; use only if clearly justified.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Micafungin can interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • Azole antifungals: increased risk of hepatotoxicity when combined.
  • Rifampin: may reduce micafungin plasma concentrations, lowering efficacy.
  • Cyclosporine: potential for elevated cyclosporine levels and toxicity.

Moderate Interactions (Monitor Closely)

  • Statins: heightened risk of myopathy or rhabdomyolysis.
  • Warfarin: possible alteration of INR, requiring closer monitoring.
  • Hormonal contraceptives: may reduce contraceptive effectiveness.

Frequently Asked Questions

Micafungin Olikla is indicated for the treatment of invasive candidiasis, esophageal candidiasis, prophylaxis of Candida infections in patients undergoing hematopoietic stem cell transplantation, and for Candida peritonitis and intra‑abdominal infections.

Micafungin blocks the enzyme β‑(1,3)‑D‑glucan synthase, preventing the synthesis of β‑(1,3)‑D‑glucan, an essential component of the fungal cell wall. This disruption weakens the wall, causing osmotic instability and fungal cell death.

The dosage of Micafungin Olikla is determined by the prescribing clinician based on the specific indication, patient weight, renal and hepatic function, and other clinical factors. Exact dosing regimens should be obtained from the treating physician.

The safety of Micafungin Olikla in pregnancy and lactation has not been established. Clinicians should evaluate the potential benefits against possible risks and consider alternative therapies when appropriate.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Micafungin belongs to the echinocandin class, which targets the fungal cell wall, unlike azoles that inhibit ergosterol synthesis. Echinocandins generally have a favorable safety profile and are effective against many Candida species, including those resistant to azoles.

Micafungin Olikla should be stored at 2‑8 °C in a refrigerator, protected from light. Do not freeze or shake the vial, and keep it in the original packaging to maintain stability.

Micafungin Olikla is supplied as an intravenous solution and is administered by slow IV infusion over a period specified by the prescriber, typically in a clinical setting such as a hospital or infusion centre.

Serious risks include hepatic failure, severe hypersensitivity reactions such as anaphylaxis, Stevens‑Johnson syndrome, renal failure, and profound neutropenia. Patients should be monitored closely for signs of these events during therapy.

Micafungin Olikla is contraindicated in patients with known hypersensitivity to micafungin or any component of the formulation. Caution is also advised for individuals with severe hepatic impairment or those receiving interacting medications that cannot be managed.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Micafungin

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT