Product image of Micardis (Telmisartan) supplied by GNH India

Micardis

Active Ingredient:
Telmisartan
Origin:
EU

Micardis (Telmisartan)

Telmisartan, the active ingredient in Micardis, is an Angiotensin II receptor blocker (ARB) presented as an oral tablet for oral use. It is prescribed to lower elevated blood pressure in adult patients and helps reduce the risk of cardiovascular complications associated with hypertension.

GNH India supplies Micardis as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with a focus on quality assurance and regulatory compliance, and a distribution network that ensures timely delivery across multiple regions.

Manufacturer / TM Owner

Boehringer Ingelheim International Gmbh

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Indications & Clinical Uses

  • Micardis (telmisartan) acts on the renin‑angiotensin‑aldosterone system to control high blood pressure.
  • Hypertension: reduces systolic and diastolic blood pressure in patients with primary (essential) hypertension, contributing to decreased risk of stroke, myocardial infarction, and other hypertension‑related cardiovascular events.
  • Essential hypertension: provides long‑lasting blood pressure control, improving overall cardiovascular health and reducing the need for additional antihypertensive agents.

How It Works

  • Telmisartan selectively blocks the angiotensin II type 1 (AT1) receptor, preventing angiotensin II from binding and triggering vasoconstriction, aldosterone release, and sympathetic activation. This inhibition leads to relaxation of vascular smooth muscle, reduced peripheral resistance, and lower blood pressure, while also attenuating sodium and water retention.

Side Effects

Telmisartan may cause a range of adverse reactions, which are generally classified by frequency.

Common Side Effects

  • Dizziness
  • Headache
  • Fatigue

Serious or Rare Side Effects

  • Angioedema
  • Renal impairment
  • Hyperkalemia

Precautions & Warnings

  • Before initiating therapy, clinicians should consider several safety measures.
  • Monitor blood pressure: ensure adequate control and avoid excessive hypotension.
  • Assess renal function: check serum creatinine and eGFR periodically.
  • Check serum potassium: monitor for hyperkalemia, especially with concomitant potassium‑sparing agents.
  • Use caution in hepatic impairment: dose adjustments may be required.
  • Avoid concurrent aliskiren in diabetic patients: increased risk of adverse renal outcomes.
  • Store at room temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Telmisartan can interact with several medicines, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid)

  • Aliskiren: combined use may cause renal dysfunction and hyperkalemia.
  • Potassium‑sparing diuretics or supplements: risk of dangerous hyperkalemia.
  • ACE inhibitors: concurrent use can increase the likelihood of angioedema and hyperkalemia.

Moderate Interactions (Monitor Closely)

  • NSAIDs: may blunt antihypertensive effect and affect renal function.
  • CYP3A4 inducers (e.g., rifampin): can lower telmisartan plasma concentrations.
  • Lithium: may increase lithium levels, necessitating serum monitoring.

Frequently Asked Questions

Micardis contains telmisartan, an angiotensin II receptor blocker indicated for the treatment of hypertension. By lowering elevated blood pressure, it helps reduce the risk of cardiovascular events such as stroke and heart attack in adult patients.

Telmisartan selectively blocks the AT1 receptor for angiotensin II, preventing vasoconstriction, aldosterone release, and sympathetic activation. This results in relaxed blood vessels, reduced peripheral resistance, and lower blood pressure.

The appropriate dose of Micardis is determined by the prescribing healthcare professional based on the individual’s blood pressure, response to therapy, and any concomitant conditions. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Telmisartan is generally contraindicated in pregnancy because it can affect fetal renal development. It is also not recommended while breastfeeding, as it may pass into breast milk. Women who are pregnant, planning pregnancy, or nursing should discuss alternative treatments with their physician.

To place an order, submit an enquiry on the Micardis product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with ACE inhibitors, telmisartan offers a similar blood‑pressure‑lowering effect but with a lower incidence of cough. Unlike calcium‑channel blockers, it directly targets the renin‑angiotensin system, providing additional benefits such as modest metabolic effects. Choice of therapy depends on patient profile and tolerability.

Micardis tablets should be stored at room temperature, below 25 °C, in the original container to protect them from moisture and light. Keep the product out of reach of children and avoid storing in humid or excessively hot environments.

Micardis is taken orally, usually once daily, with or without food. The tablet should be swallowed whole with a glass of water. Patients should not crush or chew the tablet unless specifically instructed by a healthcare professional.

Serious risks include angioedema, which can affect the face, lips, tongue or airway, and severe hyperkalemia that may cause cardiac arrhythmias. Renal impairment and marked hypotension are also important concerns, especially in patients with pre‑existing kidney disease or volume depletion.

Micardis should be avoided in patients with known hypersensitivity to telmisartan or any ARB component, in those with severe hepatic impairment, and in patients taking aliskiren who have diabetes. Caution is also advised for individuals with significant renal dysfunction or electrolyte abnormalities.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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