Product image of Micetal (Flutrimazole) supplied by GNH India

Micetal

Active Ingredient:
Flutrimazole
Origin:
EU

Micetal (Flutrimazole)

Flutrimazole, the active ingredient in Micetal, is a azole antifungal presented as a topical formulation for skin application. It acts on dermatophyte and yeast organisms that cause superficial infections, and is indicated for use in adult patients with conditions such as athlete’s foot, ringworm and jock itch. The medication is applied directly to the affected area once or twice daily as directed by a healthcare professional.

GNH India supplies Micetal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable sourcing for qualified healthcare providers.

Manufacturer / TM Owner

Noucor Health, S.A.

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Indications & Clinical Uses

Flutrimazole is used to treat fungal skin infections by targeting dermatophytes and yeasts.

  • Tinea corporis (ringworm): reduces fungal growth and clears skin lesions.
  • Tinea cruris (jock itch): alleviates itching and eradicates the infection.
  • Tinea pedis (athlete’s foot): treats the infection and prevents spread to other areas.
  • Candidal intertrigo: controls yeast overgrowth on skin folds.
  • Onychomycosis (fungal nail infection): helps reduce nail discoloration and thickness when applied to the nail bed.

How It Works

  • Flutrimazole inhibits the fungal enzyme lanosterol 14α‑demethylase, a cytochrome P450 isoform essential for converting lanosterol to ergosterol. By blocking this step, the drug disrupts the synthesis of ergosterol, a key component of fungal cell membranes, leading to increased membrane permeability and ultimately inhibiting fungal growth and replication. The inhibition is localized to the site of application, minimizing systemic exposure. This mechanism classifies flutrimazole among azole antifungals used for topical therapy.

Side Effects

Topical application of flutrimazole may be associated with local skin reactions and, rarely, systemic adverse events.

Common Side Effects

  • Mild burning or stinging at the application site.
  • Transient itching or redness.
  • Dryness or peeling of the treated skin.

Serious or Rare Side Effects

  • Severe allergic dermatitis or contact urticaria.
  • Extensive skin rash such as Stevens‑Johnson syndrome.
  • Systemic hypersensitivity reactions including fever and malaise.
  • Hepatic enzyme elevation in rare cases of extensive absorption.

Precautions & Warnings

When using flutrimazole, certain precautions should be observed to ensure safety and effectiveness.

  • Application area: apply to clean, dry skin and avoid excessive use.
  • Avoid contact with eyes, mucous membranes, or broken skin.
  • Do not use on large, inflamed or ulcerated areas without medical advice.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Concurrent skin conditions: monitor for increased irritation or infection.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Flutrimazole may interact with other medications or substances, influencing its safety profile.

Major Interactions (Avoid)

  • Concurrent systemic azole antifungals: risk of additive toxicity if large skin areas are treated.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): may increase systemic absorption.
  • Photosensitizing agents (e.g., tetracyclines): heightened risk of skin photosensitivity.

Moderate Interactions (Monitor Closely)

  • Topical corticosteroids: may reduce antifungal efficacy.
  • Other topical antifungal agents: potential for irritation or antagonistic effects.
  • Alcohol-based skin cleansers: may alter drug absorption.

Frequently Asked Questions

Micetal contains flutrimazole, a topical azole antifungal indicated for the treatment of superficial fungal skin infections such as athlete’s foot (tinea pedis), ringworm (tinea corporis) and jock itch (tinea cruris). It is applied directly to the affected area to eradicate the causative dermatophytes or yeasts.

Flutrimazole inhibits the fungal enzyme lanosterol 14α‑demethylase, blocking the conversion of lanosterol to ergosterol, an essential component of fungal cell membranes. This disruption compromises membrane integrity, leading to inhibited growth and death of the fungus at the site of application.

The prescriber determines the appropriate dosage regimen based on the infection type, severity, and patient factors. Typically, a thin layer is applied once or twice daily to the affected skin, but exact instructions must come from a qualified healthcare professional.

Safety of flutrimazole during pregnancy or lactation has not been fully established. It should be used only if the potential benefit justifies any possible risk to the fetus or infant, and the decision should be made by a qualified healthcare provider after evaluating the individual situation.

To place an order, submit an enquiry on the Micetal product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Micetal (flutrimazole) belongs to the azole class and offers a broad spectrum against dermatophytes and yeasts, similar to clotrimazole or miconazole. Compared with some alternatives, it may provide comparable efficacy with a favorable local tolerability profile, but choice of therapy depends on the specific pathogen, infection site, patient history and clinician preference.

Micetal should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture, heat and light. Keep the container tightly closed when not in use and out of reach of children. Do not freeze or expose the product to extreme temperatures.

Micetal is applied topically to the clean, dry skin area affected by the fungal infection. A thin layer is spread over the lesion and the surrounding margin, usually once or twice daily, as directed by a healthcare professional. Hands should be washed after application unless they are the treatment site.

Although rare, serious adverse reactions can include severe allergic dermatitis, extensive skin rashes such as Stevens‑Johnson syndrome, and systemic hypersensitivity responses. Any signs of swelling, blistering, fever, or widespread rash require immediate medical attention and discontinuation of the product.

Micetal should not be used by individuals with known hypersensitivity to flutrimazole or any other azole antifungal. It is also contraindicated on large areas of broken or inflamed skin, and caution is advised in patients with pre‑existing liver disease or those taking strong CYP3A4 inhibitors without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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