Product image of Miclast (Ciclopirox) supplied by GNH India

Miclast

Active Ingredient:
Ciclopirox
Origin:
EU

Miclast (Ciclopirox)

Ciclopirox, the active ingredient in Miclast, is an antifungal presented as a topical formulation for skin application. It is used to treat fungal infections of the skin and nails, including dermatophytosis, athlete’s foot, ringworm and onychomycosis, and is indicated for use in adult and pediatric patients as appropriate.

GNH India supplies Miclast as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable and efficient logistics throughout global distribution.

Manufacturer / TM Owner

Pierre Fabre Iberica, S.A.

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Indications & Clinical Uses

Miclast (ciclopirox) is a topical antifungal that acts on fungal skin infections.

  • Dermatophytosis: reduces fungal growth and promotes clearance of skin lesions.
  • Tinea pedis: alleviates itching and resolves athlete’s foot infection.
  • Tinea corporis: treats ringworm of the body, improving skin appearance.
  • Onychomycosis: penetrates the nail plate to eradicate fungal infection and improve nail health.

How It Works

  • Ciclopirox exerts its antifungal activity by chelating intracellular polyvalent cations, thereby inhibiting the activity of metal‑dependent enzymes required for sterol synthesis. This disruption impairs the formation of fungal cell membrane sterols, leading to altered membrane permeability and inhibition of fungal growth. The compound also interferes with cellular energy production and transport processes, contributing to its broad spectrum of activity against dermatophytes, yeasts and molds.

Side Effects

Topical application of Miclast may cause local skin reactions, which are generally mild and reversible.

Common Side Effects

  • Burning sensation: mild transient heat at the application site.
  • Itching: occasional localized pruritus.
  • Redness: mild erythema around the treated area.

Serious or Rare Side Effects

  • Severe allergic reaction: swelling, hives, or breathing difficulty.
  • Contact dermatitis: intense inflammation with possible blistering.
  • Stevens‑Johnson syndrome: rare severe skin eruption requiring urgent care.

Precautions & Warnings

Before using Miclast, consider the following precautions to ensure safe and effective treatment.

  • Avoid use on broken or inflamed skin: application should be limited to intact skin surfaces.
  • Do not apply to mucous membranes: keep the product away from eyes, mouth and genital areas.
  • Discontinue if severe irritation occurs: stop treatment and seek medical advice if intense redness or swelling develops.
  • Consult a healthcare professional before using other topical medications: concurrent use may increase irritation risk.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Miclast may interact with other topical agents; consider the following interaction categories.

Major Interactions (Avoid)

  • Concurrent use with other topical antifungal agents containing similar active ingredients: may increase local irritation.
  • Application over occlusive dressings: can enhance systemic absorption and cause adverse effects.

Moderate Interactions (Monitor Closely)

  • Co‑application with topical corticosteroids: may alter drug penetration and efficacy.
  • Use with photosensitizing agents (e.g., retinoids): may increase risk of phototoxic reactions.
  • Combination with other skin irritants (e.g., chemical peels): may exacerbate local skin reactions.

Frequently Asked Questions

Miclast contains ciclopirox and is applied to the skin to treat superficial fungal infections such as dermatophytosis, athlete’s foot (tinea pedis), body ringworm (tinea corporis) and nail fungus (onychomycosis). It works locally on the affected area to reduce fungal growth and promote healing.

Ciclopirox chelates metal ions that are essential for fungal enzymes involved in sterol synthesis and energy production. By disrupting these pathways, it impairs the fungal cell membrane and inhibits growth, providing a broad‑spectrum antifungal effect against dermatophytes, yeasts and molds.

The dosage of Miclast is determined by the prescribing healthcare professional based on the specific infection, location and patient characteristics. The prescriber will advise the amount to apply, frequency and duration of therapy.

Safety data for ciclopirox topical use in pregnancy and lactation are limited. Women who are pregnant, planning pregnancy or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Miclast.

To request Miclast, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Miclast (ciclopirox) offers a broad spectrum of activity and a unique mechanism that differs from azole or allylamine antifungals. It is often chosen when resistance to other classes is a concern or when a non‑systemic option is preferred for localized skin and nail infections.

Miclast should be stored at room temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture and direct sunlight, and keep it out of reach of children.

Apply a thin layer of Miclast to the clean, dry affected skin or nail surface as directed by the prescriber. Typically the product is used once or twice daily, and the treated area should be gently massaged until the film disappears.

Although rare, serious adverse reactions can include severe allergic responses such as swelling, hives, difficulty breathing, or Stevens‑Johnson syndrome. Any signs of extensive skin blistering, widespread rash or systemic symptoms should prompt immediate medical evaluation.

Miclast should be avoided in individuals with known hypersensitivity to ciclopirox or any excipients in the formulation. It is also contraindicated on severely damaged, inflamed or mucosal surfaces and should not be used in patients who cannot safely apply a topical medication.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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