Product image of Miclast (Ciclopirox Olamine) supplied by GNH India

Miclast

Active Ingredient:
Ciclopirox Olamine
Origin:
EU

Miclast (Ciclopirox Olamine)

Ciclopirox olamine, the active ingredient in Miclast, is an antifungal presented as a topical formulation for skin use. It is employed to treat fungal infections of the skin, hair and nails, including athlete’s foot, ringworm, jock itch, seborrheic dermatitis and onychomycosis, and is indicated for use in adults and children as directed by a healthcare professional.

GNH India supplies Miclast as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with established quality assurance and regulatory compliance.

Manufacturer / TM Owner

Pierre Fabre Italia S.P.A.

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Indications & Clinical Uses

Miclast (ciclopirox olamine) is a topical antifungal that acts on dermatophyte and yeast infections of the skin and nails.

  • Tinea pedis: reduces symptoms and eradicates the causative fungus on the feet.
  • Tinea corporis: clears ring‑shaped skin lesions caused by dermatophytes.
  • Tinea cruris: treats fungal infection of the groin area, relieving itching and redness.
  • Seborrheic dermatitis: controls yeast‑related scalp and facial flaking.
  • Onychomycosis: improves nail appearance by inhibiting fungal growth in the nail plate.

How It Works

  • Ciclopirox olamine interferes with fungal metal‑dependent enzymes, disrupting membrane transport and metabolic pathways essential for cell survival. By chelating intracellular metal ions, it impairs the synthesis of essential proteins and nucleic acids, leading to fungal cell death without significant systemic absorption.

Side Effects

Miclast is generally well tolerated, but local skin reactions may occur.

Common Side Effects

  • Burning sensation: mild transient heat at the application site.
  • Itching: occasional pruritus during treatment.
  • Redness: mild erythema around the treated area.
  • Dry skin: temporary dryness or flaking.
  • Scaling: superficial skin scaling.
  • Stinging: brief discomfort upon application.

Serious or Rare Side Effects

  • Allergic contact dermatitis: severe rash with swelling.
  • Urticaria: hives or widespread itching.
  • Blister formation: vesicles developing on the skin.
  • Swelling of the face or lips: angioedema.
  • Severe skin irritation: intense pain or necrosis.
  • Systemic hypersensitivity: rare anaphylactic reaction.

Precautions & Warnings

Before using Miclast, consider the following safety measures.

  • Avoid application on broken or inflamed skin: may increase irritation.
  • Do not use on extensive body surface without medical advice: risk of systemic absorption.
  • Discontinue if severe irritation occurs: seek medical evaluation.
  • Consult a physician if infection worsens or does not improve: may need alternative therapy.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Miclast has limited systemic interactions, but certain topical agents may affect its safety or efficacy.

Major Interactions (Avoid)

  • Concurrent use with other topical irritants (e.g., chemical peels): may increase skin irritation.
  • Use with systemic antifungals without supervision: potential for increased systemic exposure.
  • Application together with corticosteroid creams unless directed: may mask infection signs.

Moderate Interactions (Monitor Closely)

  • Alcohol‑based hand sanitizers applied shortly after Miclast: may reduce antifungal effectiveness.
  • Occlusive dressings over treated area: can increase local drug concentration and irritation.

Frequently Asked Questions

Miclast is a topical antifungal medication indicated for the treatment of superficial fungal infections such as athlete’s foot (tinea pedis), ringworm of the body (tinea corporis), jock itch (tinea cruris), seborrheic dermatitis, and fungal nail infections (onychomycosis). It works by eliminating the fungi that cause these skin and nail conditions.

Ciclopirox olamine, the active ingredient in Miclast, chelates metal ions that are essential for fungal enzyme activity. By inhibiting metal‑dependent enzymes, it disrupts membrane transport, protein synthesis, and energy production within fungal cells, leading to cell death and clearance of the infection.

The dosage of Miclast is determined by the prescribing healthcare professional based on the specific indication, severity of infection, patient age, and treatment area. The prescriber will provide instructions on the amount to apply, frequency, and duration of therapy.

Safety data for ciclopirox olamine in pregnancy and lactation are limited. Healthcare providers should weigh the potential benefits against any possible risks before prescribing Miclast to pregnant or breastfeeding individuals. Use only if clearly needed and directed by a qualified professional.

To request Miclast, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Miclast (ciclopirox olamine) offers a broad spectrum of activity against dermatophytes, yeasts, and some molds, and is applied topically, avoiding systemic exposure. Compared with azole creams, ciclopirox has a distinct mechanism that may be useful when resistance to azoles is suspected, though clinical choice depends on infection type and physician judgment.

Miclast should be stored at room temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed when not in use to maintain stability.

Miclast is applied topically to the affected skin or nail area. The prescriber will advise the amount to use, typically a thin layer, and the frequency (often once or twice daily). Hands should be washed before and after application, and the treated area should be clean and dry.

While generally well tolerated, Miclast can cause severe skin reactions such as allergic contact dermatitis, urticaria, blistering, facial or lip swelling (angioedema), and rare systemic hypersensitivity. Patients should discontinue use and seek medical attention if any of these serious symptoms develop.

Miclast should not be used on patients with known hypersensitivity to ciclopirox olamine or any of the formulation excipients. It is also contraindicated on extensive broken skin, mucous membranes, or in individuals where a systemic antifungal is required without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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