Product image of Miconal (Miconazole) supplied by GNH India

Miconal

Active Ingredient:
Miconazole
Origin:
EU

Miconal (Miconazole)

Miconazole, the active ingredient in Miconal, is an imidazole antifungal presented as a topical formulation for cutaneous use. It treats superficial fungal infections such as athlete's foot, jock itch and ringworm in both adults and children.

GNH India supplies Miconal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Tarchomińskie Zakłady Farmaceutyczne "polfa" Spółka Akcyjna

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Indications & Clinical Uses

Miconazole is used to treat fungal skin infections caused by dermatophytes and yeasts.

  • Athlete's foot (tinea pedis): eliminates the causative fungus and relieves itching and scaling.
  • Jock itch (tinea cruris): clears the infection and reduces redness and discomfort.
  • Ringworm (tinea corporis): eradicates the dermatophyte and promotes healing of skin lesions.
  • Candidal intertrigo: controls yeast overgrowth in skin folds and alleviates irritation.
  • Diaper rash (candidal): reduces yeast proliferation and soothes inflamed skin.

How It Works

  • Miconazole inhibits ergosterol synthesis by blocking the fungal enzyme lanosterol 14α‑demethylase. This disruption compromises the cell membrane integrity of susceptible fungi, leading to increased permeability, leakage of intracellular contents and ultimately fungal cell death.

Side Effects

Topical application of miconazole may cause local skin reactions.

Common Side Effects

  • Burning sensation: mild to moderate discomfort at the application site.
  • Itching: transient pruritus following use.
  • Redness: localized erythema.
  • Dryness: skin may become flaky or dry.
  • Rash: mild dermatitis in some users.
  • Stinging: brief sharp sensation.

Serious or Rare Side Effects

  • Allergic reaction: swelling, hives or severe itching.
  • Contact urticaria: rapid onset wheal formation.
  • Severe dermatitis: extensive inflammation or blistering.
  • Stevens‑Johnson syndrome: rare but life‑threatening skin reaction.
  • Angioedema: swelling of deeper skin layers.
  • Systemic absorption effects: unlikely but possible in extensive use.

Precautions & Warnings

Before using Miconal, consider the following safety measures.

  • Avoid use on broken skin: may increase systemic absorption.
  • Do not apply to mucous membranes: formulation is for cutaneous use only.
  • Limit use to prescribed area: excessive application can cause irritation.
  • Discontinue if allergic reaction occurs: seek medical advice.
  • Keep away from eyes: rinse thoroughly if contact occurs.
  • Store at room temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Miconal may interact with other medications when absorbed systemically or when used concurrently on the skin.

Major Interactions (Avoid)

  • Oral anticoagulants (e.g., warfarin): increased bleeding risk.
  • Systemic azole antifungals (e.g., ketoconazole): additive inhibition of CYP enzymes.

Moderate Interactions (Monitor Closely)

  • Topical corticosteroids: may enhance skin irritation.
  • Other topical antifungals: risk of cumulative irritation.
  • Skin care products containing alcohol: may increase dryness.
  • Herbal creams with essential oils: potential for allergic synergy.

Frequently Asked Questions

Miconal contains miconazole, an imidazole antifungal that is applied to the skin to treat superficial fungal infections such as athlete's foot, jock itch, ringworm, candidal intertrigo and diaper rash caused by dermatophytes or yeasts.

Miconazole blocks the fungal enzyme lanosterol 14α‑demethylase, which is essential for producing ergosterol, a key component of fungal cell membranes. Without ergosterol, the membrane becomes permeable, leading to leakage of cellular contents and death of the fungus.

The dosage of Miconal is determined by the prescribing healthcare professional based on the infection type, severity and patient age. The prescriber will specify the amount to apply, frequency and duration of treatment.

Safety data for topical miconazole in pregnancy and lactation are limited. Healthcare providers usually weigh the benefits against potential risks. Women who are pregnant, planning pregnancy or breastfeeding should discuss use with their doctor before starting treatment.

To request Miconal, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Miconal (miconazole) belongs to the imidazole class, offering broad‑spectrum activity against dermatophytes and yeasts. Compared with allylamine agents such as terbinafine, miconazole has a similar efficacy for many skin infections but may be preferred for its anti‑inflammatory properties and lower systemic absorption when used topically.

Store Miconal at room temperature, below 25 °C. Keep the tube or container tightly closed, protect it from moisture and direct sunlight, and store it in its original packaging until use.

Clean and dry the affected skin area before applying a thin layer of Miconal. Gently rub it in until it disappears, usually twice daily or as directed by the prescriber. Wash hands after application unless the hands are the treatment site.

Although rare, serious adverse reactions can include severe allergic responses such as angioedema, Stevens‑Johnson syndrome or extensive dermatitis. If any signs of a severe skin reaction or systemic allergy appear, stop using the product and seek immediate medical attention.

Miconal should not be used by individuals with a known hypersensitivity to miconazole or any component of the formulation. It is also contraindicated on broken skin, mucous membranes or in patients who have experienced severe reactions to other topical antifungals.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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