Product image of Miconazol Zinkpaste Acis (Miconazole Nitrate, Zinc Oxide) supplied by GNH India

Miconazol Zinkpaste Acis

Active Ingredient:
Miconazole Nitrate, Zinc Oxide
Origin:
EU

Miconazol Zinkpaste Acis (Miconazole Nitrate, Zinc Oxide)

Miconazole nitrate, the active ingredient in Miconazol Zinkpaste Acis, is an imidazole antifungal presented as a paste for topical use. It treats superficial fungal skin infections such as tinea corporis, tinea pedis and cutaneous candidiasis in both adults and children.

GNH India supplies Miconazol Zinkpaste Acis as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑compliant documentation for global distribution.

Manufacturer / TM Owner

Acis Arzneimittel Gmbh

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Indications & Clinical Uses

Miconazol Zinkpaste Acis, an imidazole antifungal, is used to treat fungal skin conditions by inhibiting pathogen growth.

  • Tinea corporis: reduces fungal proliferation and promotes resolution of body ringworm lesions.
  • Tinea pedis: alleviates itching and clears fungal infection of the feet.
  • Cutaneous candidiasis: controls skin Candida overgrowth and supports healing of affected areas.

How It Works

  • Miconazole nitrate interferes with fungal cell‑membrane synthesis by inhibiting the enzyme lanosterol 14α‑demethylase, blocking conversion of lanosterol to ergosterol. This disruption compromises membrane integrity, leading to fungal cell death. Zinc oxide in the paste forms a protective barrier on the skin and exerts a mild astringent effect, enhancing the local antifungal activity.

Side Effects

Topical application of Miconazol Zinkpaste Acis may be associated with local skin reactions.

Common Side Effects

  • Mild burning sensation: transient feeling of warmth at the application site.
  • Itching: occasional pruritus around the treated area.
  • Redness: mild erythema that usually resolves spontaneously.
  • Dryness: slight skin dryness or flaking.

Serious or Rare Side Effects

  • Severe allergic reaction: signs include swelling, hives, or difficulty breathing.
  • Contact dermatitis: intense inflammation, blistering, or oozing at the site.
  • Systemic absorption effects: rare systemic toxicity such as liver enzyme elevation.

Precautions & Warnings

When using Miconazol Zinkpaste Acis, observe the following precautions to ensure safe and effective treatment.

  • Apply to intact skin: avoid broken or inflamed areas unless directed by a healthcare professional.
  • Duration of therapy: limit use to the prescribed period to prevent resistance.
  • Concurrent skin products: do not apply other topical medications or cosmetics on the same area without guidance.
  • Allergy assessment: discontinue if signs of hypersensitivity appear.
  • Pediatric use: consult a clinician before treating children under two years of age.
  • Pregnancy and lactation: discuss potential risks with a healthcare provider.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Miconazol Zinkpaste Acis can interact with other topical agents and systemic medications that affect fungal metabolism.

Major Interactions (Avoid)

  • Systemic azole antifungals: concurrent use may increase risk of systemic toxicity.
  • Topical corticosteroids: may reduce antifungal efficacy when applied to the same site.

Moderate Interactions (Monitor Closely)

  • Hair dyes or chemical depilatories: may irritate skin if used near the treated area.
  • Other topical antibiotics: monitor for combined skin irritation.
  • Alcohol‑based cleansers: may enhance skin absorption and cause irritation.

Frequently Asked Questions

Miconazol Zinkpaste Acis is a topical paste that combines miconazole nitrate and zinc oxide to treat superficial fungal skin infections such as tinea corporis (body ringworm), tinea pedis (athlete's foot) and cutaneous candidiasis. It works by directly targeting the fungi on the skin surface and providing a protective barrier.

Miconazole nitrate belongs to the imidazole class of antifungals. It blocks the fungal enzyme lanosterol 14α‑demethylase, which is essential for converting lanosterol to ergosterol, a key component of the fungal cell membrane. Inhibiting this step disrupts membrane integrity, leading to fungal cell death.

The specific amount and frequency of application are determined by the prescribing healthcare professional based on the infection type, severity, patient age and skin condition. Typically, a thin layer is applied to the affected area once or twice daily for the duration recommended by the prescriber.

Safety data for topical miconazole nitrate and zinc oxide during pregnancy or lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their physician before using this product.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets. After verification of trade or institutional credentials, the sales team will provide pricing, availability, shipping details and any required import documentation.

Compared with cream or solution formulations, the paste provides a thicker, longer‑lasting barrier that can enhance contact time on moist or difficult‑to‑cover areas. The addition of zinc oxide offers a soothing, astringent effect, while the miconazole component delivers the same broad‑spectrum antifungal activity found in other imidazole products.

Store the paste at room temperature, preferably below 25 °C, in its original container. Protect it from excessive moisture, direct sunlight and extreme temperatures. Keep the lid tightly closed when not in use to maintain product stability.

Clean and gently dry the affected skin area before use. Apply a thin, even layer of the paste to the lesion and surrounding skin, rubbing lightly until it is absorbed. Wash hands after application unless the hands are the treatment site. Follow the prescriber’s instructions regarding frequency and duration.

Although rare, serious adverse reactions can include severe allergic responses such as swelling, hives, or difficulty breathing, and intense contact dermatitis with blistering or oozing. If any of these symptoms develop, discontinue use immediately and seek medical attention.

Individuals with a known hypersensitivity to miconazole nitrate, zinc oxide or any other component of the paste should avoid its use. It is also contraindicated on severely damaged or ulcerated skin unless directed by a physician, and should be used with caution in young children without professional guidance.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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