Product image of Miconazolnitraat Sanias (Miconazole Nitrate) supplied by GNH India

Miconazolnitraat Sanias

Active Ingredient:
Miconazole Nitrate
Origin:
EU

Miconazolnitraat Sanias (Miconazole Nitrate)

Miconazole nitrate, the active ingredient in Miconazolnitraat Sanias, is an imidazole antifungal presented as a topical preparation for external use. It treats superficial fungal infections of the skin and mucous membranes in adults and children.

GNH India supplies Miconazolnitraat Sanias as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aurobindo Pharma B.V.

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Indications & Clinical Uses

  • Miconazole nitrate is applied topically to manage fungal infections of the skin and related structures.
  • Athlete's foot (tinea pedis): reduces itching and clears the infection.
  • Jock itch (tinea cruris): alleviates redness and eliminates the fungus.
  • Ringworm (tinea corporis): resolves lesions and prevents spread.

How It Works

  • Miconazole nitrate inhibits ergosterol synthesis by blocking the fungal cytochrome P450 enzyme lanosterol 14α-demethylase. This disruption compromises the fungal cell membrane, leading to increased permeability and ultimately cell death, thereby eliminating the infection at the site of application.

Side Effects

Common Side Effects

  • Burning sensation at the application site.
  • Itching or mild irritation.
  • Redness of the skin.
  • Dryness or peeling.
  • Mild stinging.
  • Slight swelling.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis).
  • Contact dermatitis with extensive rash.
  • Swelling of face, lips, or tongue.
  • Blistering or ulceration of the skin.
  • Persistent worsening of infection.
  • Systemic hypersensitivity reactions.

Precautions & Warnings

  • Before using, consider the following precautions.
  • Avoid use on broken skin: discontinue if irritation develops.
  • Do not apply to eyes or mucous membranes: avoid accidental contact.
  • Limit use to prescribed area: avoid excessive application.
  • Consult healthcare professional if infection persists beyond 2 weeks: seek evaluation.
  • Store at below 25°C: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Miconazole nitrate may interact with other topical or systemic agents.

Major Interactions (Avoid)

  • Concurrent use with other topical antifungals: may increase skin irritation.
  • Use with corticosteroid creams: may reduce antifungal efficacy.

Moderate Interactions (Monitor Closely)

  • Systemic azole antifungals (e.g., itraconazole): may increase systemic absorption.
  • Alcohol‑based skin products: may cause burning.
  • Chemotherapeutic agents applied to the same area: monitor for skin toxicity.

Frequently Asked Questions

Miconazolnitraat Sanias contains miconazole nitrate, an imidazole antifungal applied topically to treat superficial fungal infections such as athlete's foot (tinea pedis), jock itch (tinea cruris) and ringworm (tinea corporis). It works on the skin surface to eliminate the causative fungi.

Miconazole nitrate blocks the fungal enzyme lanosterol 14α‑demethylase, a key step in ergosterol synthesis. By preventing ergosterol formation, the drug disrupts the fungal cell membrane, increasing permeability and leading to cell death, which clears the infection at the site of application.

The dosage and frequency are determined by the prescribing healthcare professional based on the infection type, severity, patient age and the specific product formulation. Patients should follow the prescriber’s instructions and the product label for proper application.

The safety of topical miconazole nitrate in pregnancy or while breastfeeding has not been definitively established. Women who are pregnant, planning pregnancy, or nursing should discuss potential risks and benefits with their healthcare provider before using the product.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Miconazolnitraat Sanias uses miconazole nitrate, an imidazole class antifungal, which is effective against a broad range of dermatophytes and yeasts. Compared with allylamine agents such as terbinafine, imidazoles often have a broader spectrum but may be associated with more local irritation. Choice depends on infection type, patient tolerance and clinician preference.

Store the product at temperatures below 25 °C, in its original packaging, protected from moisture, heat and direct sunlight. Do not freeze. Proper storage helps maintain the stability and efficacy of the topical formulation.

The product is applied topically to the affected skin area. Clean and dry the area before use, then spread a thin layer of the cream or ointment as directed by the prescriber, usually twice daily or as indicated on the label. Wash hands after application unless treating the hands.

Serious risks include severe allergic reactions such as anaphylaxis, extensive contact dermatitis, swelling of the face or lips, and worsening of the infection despite treatment. If any of these occur, discontinue use immediately and seek medical attention.

Individuals with known hypersensitivity to miconazole nitrate or any other component of the formulation should avoid using the product. It should also not be applied to broken skin, eyes, or mucous membranes, and patients with severe liver disease should consult a physician before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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