Product image of Micotar (Miconazole) supplied by GNH India

Micotar

Active Ingredient:
Miconazole
Origin:
EU

Micotar (Miconazole)

Miconazole, the active ingredient in Micotar, is an imidazole antifungal presented as a buccal formulation for buccal use. It treats oral candidiasis by eradicating Candida species and relieving symptoms such as soreness, burning, and altered taste. The buccal delivery provides direct contact with the oral mucosa, offering localized antifungal activity while limiting systemic exposure.

GNH India supplies Micotar as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU GMP standards and provides reliable logistics for global distribution.

Manufacturer / TM Owner

Dermapharm Ag

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Indications & Clinical Uses

  • Micotar (miconazole) is used to treat fungal infections of the oral cavity.
  • Oral candidiasis: reduces fungal growth and relieves soreness, burning and taste disturbances.
  • Denture‑associated stomatitis: helps control Candida overgrowth on denture surfaces.
  • Oropharyngeal candidiasis: treats infection that extends to the throat.

How It Works

  • Miconazole inhibits the fungal enzyme lanosterol 14α‑demethylase, a key step in ergosterol synthesis. By blocking this pathway, the drug disrupts cell membrane formation, leading to increased membrane permeability and ultimately fungal cell death. The localized buccal application concentrates the effect at the site of infection while minimizing systemic exposure.

Side Effects

Miconazole buccal preparations are generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Altered taste or metallic taste.
  • Mild oral irritation or burning sensation.
  • Nausea or mild gastrointestinal discomfort.
  • Dry mouth.
  • Localized itching or redness.

Serious or Rare Side Effects

  • Severe allergic reactions including rash, swelling, or anaphylaxis.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Hepatic dysfunction manifested by jaundice or elevated liver enzymes.
  • Unexplained fever or systemic symptoms.
  • Persistent or worsening oral lesions.

Precautions & Warnings

Before using Micotar, consider the following safety measures.

  • Hypersensitivity assessment: avoid if known allergy to miconazole or other imidazoles.
  • Liver function: use with caution in patients with hepatic impairment.
  • Drug interactions: review concomitant medications that affect CYP450 enzymes.
  • Extent of use: limit application to the prescribed area to reduce systemic absorption.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Store at ambient temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Miconazole may interact with other medicines; monitor as indicated.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): may increase systemic exposure.
  • Systemic azole antifungals: additive toxicity risk.

Moderate Interactions (Monitor Closely)

  • Warfarin: potential increase in anticoagulant effect.
  • Rifampin or other CYP inducers: may reduce miconazole efficacy.
  • Oral contraceptives: possible reduction in hormonal effectiveness.
  • Antacids containing aluminum or magnesium: may affect absorption.

Frequently Asked Questions

Micotar contains the antifungal agent miconazole and is indicated for the treatment of oral candidiasis, including thrush and related mucosal fungal infections. It works locally in the mouth to eliminate Candida species and relieve associated symptoms.

Miconazole inhibits the fungal enzyme lanosterol 14α‑demethylase, blocking ergosterol synthesis essential for fungal cell membranes. This disruption leads to increased membrane permeability and fungal cell death, providing targeted antifungal activity at the site of application.

The dosage and duration of Micotar are determined by the prescribing healthcare professional based on the severity of the infection and patient-specific factors. Patients should follow the prescriber’s instructions and the product label.

Safety of miconazole buccal products in pregnancy or lactation has not been definitively established. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Micotar.

To request Micotar, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Micotar delivers miconazole directly to the oral cavity, offering rapid local action with minimal systemic exposure. Compared with systemic azoles, it reduces the risk of systemic side effects, while providing efficacy comparable to other topical agents such as clotrimazole lozenges for oral candidiasis.

Micotar should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed when not in use.

Micotar is applied buccally, meaning the tablet or lozenge is placed in the mouth and allowed to dissolve slowly, ensuring contact with the oral mucosa. Patients should follow the prescribed frequency and avoid swallowing the product whole before it dissolves.

Serious adverse reactions, although rare, include severe allergic responses such as anaphylaxis, Stevens‑Johnson syndrome, toxic epidermal necrolysis, and hepatic dysfunction. Any signs of rash, fever, jaundice, or difficulty breathing should prompt immediate medical attention.

Micotar should not be used by individuals with a known hypersensitivity to miconazole or other imidazole antifungals. Patients with severe liver disease or those taking contraindicated medications that strongly interact with miconazole should also avoid its use unless directed by a clinician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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