Product image of Micoxolamina (Ciclopirox Olamine) supplied by GNH India

Micoxolamina

Active Ingredient:
Ciclopirox Olamine
Origin:
EU

Micoxolamina (Ciclopirox Olamine)

Ciclopirox olamine, the active ingredient in Micoxolamina, is an antifungal presented as a topical formulation for skin application. It is used to treat superficial fungal infections of the skin and nails, providing a broad‑spectrum option for patients with dermatophyte, yeast, or mold infections and are commonly prescribed by dermatologists.

GNH India supplies Micoxolamina as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for cross‑border distribution.

Manufacturer / TM Owner

Mastelli S.R.L.

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Indications & Clinical Uses

Micoxolamina is a topical antifungal that targets superficial fungal infections of the skin and nails.

  • Athlete’s foot (tinea pedis): reduces fungal growth and alleviates itching and scaling.
  • Ringworm (tinea corporis): clears lesions and prevents spread.
  • Nail fungus (onychomycosis): improves nail appearance and reduces fungal load.

How It Works

  • Ciclopirox olamine interferes with fungal sterol synthesis, disrupting the formation of cell membrane components essential for fungal growth. By chelating polyvalent cations, it also impairs essential metal‑dependent enzymes, leading to loss of membrane integrity and inhibition of fungal metabolism, ultimately causing cell death.

Side Effects

Micoxolamina may cause local skin reactions when applied.

Common Side Effects

  • Irritation: mild burning or stinging at the application site.
  • Redness: localized erythema around the treated area.
  • Dryness: skin may become dry or flaky.
  • Itching: occasional pruritus during treatment.
  • Scaling: superficial skin flaking.

Serious or Rare Side Effects

  • Allergic contact dermatitis: severe rash with swelling.
  • Bullous dermatitis: blister formation on the skin.
  • Photosensitivity: increased sensitivity to sunlight.
  • Systemic absorption reactions: rare hepatic or renal effects.
  • Severe skin necrosis: extensive tissue damage (very rare).

Precautions & Warnings

When using Micoxolamina, consider the following safety measures.

  • Avoid use on damaged skin: do not apply to open wounds or severe eczema.
  • Limit exposure to eyes: keep product away from the ocular area.
  • Do not use on mucous membranes: avoid oral, genital, or anal mucosa.
  • Discontinue if severe irritation occurs: seek medical advice promptly.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Micoxolamina has a low potential for systemic drug interactions, but topical co‑applications may affect tolerability.

Major Interactions (Avoid)

  • Concurrent use with other topical irritants: may increase skin irritation.
  • Use with systemic antifungals that share hepatic metabolism: monitor liver function.

Moderate Interactions (Monitor Closely)

  • Co‑application with corticosteroid creams: may reduce antifungal efficacy.
  • Use with phototoxic agents: increase risk of photosensitivity.
  • Combination with other topical medications: assess for additive irritation.

Frequently Asked Questions

Micoxolamina is a topical antifungal medication indicated for the treatment of superficial fungal skin infections, including athlete’s foot, ringworm, and nail fungus. It works on the skin surface to eliminate the fungi responsible for these conditions.

Ciclopirox olamine disrupts fungal cell membranes by inhibiting sterol synthesis and chelating essential metal ions, which impairs enzyme activity. This dual action compromises fungal cell integrity and metabolism, leading to cell death and clearance of the infection.

The dosage of Micoxolamina is determined by the prescribing healthcare professional based on the infection type, severity, and patient characteristics. The prescriber will specify the amount to apply, frequency, and duration of treatment.

Safety data for Micoxolamina in pregnancy and lactation are limited. Healthcare providers should evaluate the potential benefits against any possible risks before prescribing it to pregnant or nursing individuals.

To order Micoxolamina, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Micoxolamina (ciclopirox olamine) offers a broad spectrum of activity against dermatophytes, yeasts, and molds, similar to other topical agents like terbinafine or clotrimazole. Its unique mechanism of sterol synthesis inhibition and metal chelation can be advantageous in resistant cases, though clinical choice depends on infection type and physician preference.

Store Micoxolamina at room temperature, preferably below 25 °C, in its original packaging. Keep it away from excessive moisture, heat, and direct sunlight to maintain product stability and efficacy.

Micoxolamina is applied topically to the affected skin area. The prescriber will advise the amount to use, typically a thin layer, and the frequency—often once or twice daily—until the infection resolves.

Serious risks, though rare, include severe allergic reactions such as contact dermatitis, bullous skin eruptions, and photosensitivity. If any signs of a severe skin reaction or systemic symptoms appear, discontinue use and seek immediate medical attention.

Micoxolamina should not be used on broken or severely inflamed skin, on mucous membranes, or in individuals with known hypersensitivity to ciclopirox olamine or any formulation components. Patients with extensive skin disease should consult a healthcare professional before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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