Product image of Micrazym (Amylase, Lipase, Protease) supplied by GNH India

Micrazym

Active Ingredient:
Amylase, Lipase, Protease
Origin:
EU

Micrazym (Amylase, Lipase, Protease)

Amylase, Lipase, Protease, the active ingredients in Micrazym, constitute an oral enzyme supplement formulated to aid the digestive process. The product provides a combination of pancreatic enzymes that support the breakdown of carbohydrates, fats, and proteins in patients with exocrine pancreatic insufficiency, such as those with cystic fibrosis, chronic pancreatitis, or after pancreatic surgery.

GNH India supplies Micrazym as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to strict quality standards and provides regulatory documentation for import and distribution.

Manufacturer / TM Owner

Alfasigma S.P.A.

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Indications & Clinical Uses

Micrazym is used to supplement pancreatic enzyme activity in conditions characterized by exocrine pancreatic insufficiency.

  • Cystic fibrosis: improves digestion and nutrient absorption by providing essential pancreatic enzymes.
  • Chronic pancreatitis: reduces steatorrhea and abdominal discomfort through enzyme supplementation.
  • Post‑pancreatic surgery: aids in the breakdown of fats, proteins, and carbohydrates to support nutritional status.

How It Works

  • Micrazym delivers a blend of amylase, lipase, and protease that act directly in the gastrointestinal lumen. Amylase catalyzes the hydrolysis of starches into sugars, lipase hydrolyzes triglycerides into fatty acids and monoglycerides, and protease cleaves peptide bonds to release amino acids. By restoring these enzymatic activities, the product compensates for deficient pancreatic secretion and facilitates normal macronutrient digestion and absorption.

Side Effects

Micrazym may be associated with gastrointestinal and hypersensitivity reactions, ranging from mild to serious.

Common Side Effects

  • Abdominal discomfort: mild pain or cramping after dosing.
  • Flatulence: increased gas production.
  • Diarrhea: loose stools, especially at higher doses.
  • Nausea: feeling of queasiness.
  • Steatorrhea: oily stools due to incomplete fat digestion.
  • Vomiting: occasional emesis after taking the product.

Serious or Rare Side Effects

  • Allergic reaction: rash, itching, swelling, or anaphylaxis.
  • Pancreatitis exacerbation: worsening abdominal pain with elevated enzymes.

Precautions & Warnings

When using Micrazym, consider the following precautions.

  • Dose titration: adjust dose based on clinical response and stool fat content.
  • Allergy screening: avoid if known hypersensitivity to any enzyme component.
  • Renal/hepatic impairment: monitor closely and consider dose reduction.
  • Pregnancy and lactation: use only if benefit outweighs potential risk, as data are limited.
  • Drug interactions: assess concomitant use of acid‑suppressing agents that may affect enzyme activity.
  • Store at ambient temperature below 25°C: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Micrazym can interact with other medicines; review the following.

Major Interactions (Avoid)

  • Proton pump inhibitors: may reduce enzyme activation in the acidic environment of the stomach.
  • Antacids containing aluminum or magnesium: can bind enzymes and diminish their efficacy.

Moderate Interactions (Monitor Closely)

  • Orlistat: may interfere with fat digestion and alter lipase activity.
  • Antibiotics altering gut flora: could affect enzyme activity indirectly.
  • High‑dose vitamin supplements: may cause gastrointestinal upset when combined with the product.

Frequently Asked Questions

Micrazym is an oral enzyme supplement that provides amylase, lipase, and protease to support digestion in patients with exocrine pancreatic insufficiency, such as those with cystic fibrosis, chronic pancreatitis, or who have undergone pancreatic surgery.

The three enzymes act in the gastrointestinal tract: amylase breaks down starches into sugars, lipase hydrolyzes dietary fats into fatty acids and monoglycerides, and protease cleaves proteins into amino acids. Together they replace deficient pancreatic secretions and improve nutrient absorption.

The appropriate dose of Micrazym is determined by the prescribing healthcare professional based on the individual’s clinical condition, severity of enzyme deficiency, and nutritional needs. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for Micrazym in pregnancy and lactation are limited. It should be used only if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision should be made by a qualified healthcare provider.

To request Micrazym, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Micrazym contains a balanced blend of amylase, lipase, and protease, similar to other pancreatic enzyme replacement therapies. Its formulation is designed for oral administration and may differ in enzyme potency, capsule size, or excipients, which can affect tolerability and dosing frequency compared with alternative brands.

Micrazym should be stored at ambient temperature below 25 °C, in its original packaging, protected from moisture, heat and direct sunlight. Keeping the product in a dry place helps maintain enzyme activity throughout its shelf life.

Micrazym is taken orally, usually with meals or snacks to coincide with food intake. The tablets or capsules should be swallowed whole with a sufficient amount of water unless otherwise directed by a healthcare professional.

Serious risks, although rare, include allergic reactions such as rash, swelling, or anaphylaxis, and possible exacerbation of pancreatitis. Patients should seek immediate medical attention if they experience signs of a severe allergic response or worsening abdominal pain.

Micrazym should not be used by individuals with a known hypersensitivity to any of its enzyme components or excipients. It is also contraindicated in patients with active pancreatitis until the condition is stabilized, and caution is advised in those with severe renal or hepatic impairment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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