Product image of Microgeste (Ethinylestradiol, Gestodene | Lactose Monohydrate) supplied by GNH India

Microgeste

Active Ingredient:
Ethinylestradiol, Gestodene | Lactose Monohydrate
Origin:
EU

Microgeste (Ethinylestradiol, Gestodene | Lactose Monohydrate)

Ethinylestradiol and Gestodene, the active ingredients in Microgeste, are a combined oral contraceptive presented as a tablet for oral use. They prevent pregnancy by suppressing ovulation and altering cervical mucus in women of reproductive age.

GNH India supplies Microgeste as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bayer Portugal Lda

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Indications & Clinical Uses

Microgeste is a combined hormonal contraceptive indicated for preventing pregnancy in women of child‑bearing potential.

  • Contraception: provides reliable hormonal birth control to prevent unintended pregnancy.
  • Family planning: offers a reversible method for women seeking long‑term pregnancy prevention.
  • Menstrual regulation: helps maintain a regular menstrual cycle while on therapy.

How It Works

  • Ethinylestradiol and Gestodene act together to suppress the hypothalamic‑pituitary‑ovarian axis. Ethinylestradiol provides estrogenic activity, while Gestodene supplies progestogenic activity. The combination inhibits the mid‑cycle surge of luteinising hormone (LH) and follicle‑stimulating hormone (FSH), preventing ovulation. It also thickens cervical mucus and induces endometrial changes that reduce the likelihood of implantation.

Side Effects

Microgeste may cause a range of adverse reactions. Patients should be aware of both common and serious possibilities.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Breast tenderness: discomfort or swelling of the breasts.
  • Headache: intermittent mild to moderate pain.
  • Spotting: irregular vaginal bleeding between periods.
  • Mood changes: fluctuations in emotional state.
  • Weight gain: modest increase in body weight.

Serious or Rare Side Effects

  • Deep vein thrombosis: blood clot formation in the legs.
  • Pulmonary embolism: clot migration to the lungs.
  • Stroke: cerebrovascular accident due to clotting.
  • Myocardial infarction: heart attack risk.
  • Severe allergic reaction: rash, swelling, or anaphylaxis.
  • Liver tumor: rare hepatic neoplasm.

Precautions & Warnings

Before prescribing Microgeste, clinicians should consider several safety aspects.

  • Assess thrombotic risk: evaluate personal and family history of clotting disorders.
  • Avoid smoking: especially in women over 35 years of age.
  • Monitor blood pressure: hypertension may increase cardiovascular risk.
  • Review liver function: hepatic impairment can alter drug metabolism.
  • Store at ambient temperature: keep below 25°C, protect from moisture and light.

Avoid Interactions

Microgeste can interact with other medicines, affecting efficacy or safety.

Major Interactions (Avoid)

  • Strong enzyme inducers (e.g., rifampin, carbamazepine): may reduce contraceptive effectiveness.
  • Certain antiretrovirals (e.g., efavirenz): can lower hormone levels and increase failure risk.
  • Additional hormonal therapy (e.g., estrogen replacement): may heighten thrombosis risk.

Moderate Interactions (Monitor Closely)

  • Some antibiotics (e.g., tetracycline): may slightly diminish contraceptive efficacy.
  • Antihypertensives (e.g., ACE inhibitors): may affect blood pressure control.
  • Herbal supplements (e.g., St. John’s wort): can lower hormone concentrations.

Frequently Asked Questions

Microgeste is prescribed as a combined oral contraceptive to prevent unintended pregnancy. It provides a reversible, hormone‑based method of birth control for women of reproductive age who require reliable contraception.

The ethinylestradiol component supplies estrogen activity, while gestodene provides progestogenic activity. Together they suppress the mid‑cycle surge of luteinising hormone and follicle‑stimulating hormone, preventing ovulation, and they also thicken cervical mucus and alter the endometrium to reduce the chance of implantation.

The dosing regimen for Microgeste is determined by the prescribing clinician. Typically, a single tablet is taken once daily at the same time each day, but the exact schedule and duration are individualized based on patient needs and medical guidance.

Microgeste is not indicated for use during pregnancy and should be discontinued if pregnancy occurs. Limited data are available for breastfeeding; because estrogen may affect milk production, clinicians usually advise caution and consider alternative contraception for nursing mothers.

To request Microgeste, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Microgeste contains ethinylestradiol and gestodene, a low‑dose estrogen‑progestin combination that offers a favorable bleeding profile and high contraceptive efficacy. Compared with older formulations that use higher estrogen doses, Microgeste may present a lower risk of estrogen‑related side effects while maintaining comparable pregnancy‑prevention rates.

Store Microgeste tablets at ambient temperature, below 25 °C, in the original blister pack. Protect them from moisture, excessive heat and direct sunlight. Keep the container tightly closed and out of reach of children.

Microgeste is taken orally with a glass of water, preferably at the same time each day. The tablet should be swallowed whole and not chewed or broken. Consistent daily intake maximizes contraceptive effectiveness.

Serious risks include venous thromboembolism such as deep‑vein thrombosis, pulmonary embolism, stroke, and myocardial infarction. Rare but severe allergic reactions and liver tumors have also been reported. Patients should seek immediate medical attention if they experience symptoms like sudden leg pain, shortness of breath, chest pain, severe headache, or unexplained swelling.

Microgeste is contraindicated in women with a history of thromboembolic disorders, uncontrolled hypertension, active liver disease, known or suspected breast cancer, or those who are pregnant. It should also be avoided by smokers over 35 years of age and by individuals with known hypersensitivity to any component of the tablet.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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