Product image of Microgyn (Ethinylestradiol, Levonorgestrel) supplied by GNH India

Microgyn

Active Ingredient:
Ethinylestradiol, Levonorgestrel
Origin:
EU

Microgyn (Ethinylestradiol, Levonorgestrel)

Ethinylestradiol, the active ingredient in Microgyn, is a combined oral contraceptive presented as an oral tablet for oral use. It works with levonorgestrel to prevent pregnancy by regulating hormonal cycles.

GNH India supplies Microgyn as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bayer Ab

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Indications & Clinical Uses

  • Microgyn, a combined oral contraceptive, is used to prevent pregnancy by acting on the hormonal regulation of the menstrual cycle.
  • Contraception: prevents unintended pregnancy when taken as prescribed.
  • Menstrual cycle regulation: helps achieve predictable monthly bleeding patterns.
  • Acne management: may improve acne associated with androgen excess.

How It Works

  • Ethinylestradiol and levonorgestrel act on the hypothalamic‑pituitary‑ovarian axis, suppressing the mid‑cycle surge of luteinizing hormone (LH) and follicle‑stimulating hormone (FSH) to inhibit ovulation. The progestin component also thickens cervical mucus and induces endometrial changes that reduce the likelihood of implantation.

Side Effects

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Headache: tension‑type or migraine‑like pain.
  • Breast tenderness: swelling or soreness.
  • Spotting: irregular bleeding between periods.

Serious or Rare Side Effects

  • Venous thromboembolism: blood clots in deep veins.
  • Stroke: cerebrovascular accident, especially in high‑risk patients.
  • Severe allergic reaction: anaphylaxis with rash, swelling, and breathing difficulty.

Precautions & Warnings

Before prescribing Microgyn, clinicians should consider several safety factors.

  • Cardiovascular risk assessment: evaluate history of thrombosis or smoking.
  • Liver function review: avoid in severe hepatic impairment.
  • Breast cancer screening: discuss if personal or family history exists.
  • Missed tablet guidance: provide clear instructions for missed doses.
  • Pregnancy avoidance: advise against use during known or suspected pregnancy.
  • Store at room temperature: keep in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Microgyn may interact with other medicines, altering its effectiveness.

Major Interactions (Avoid)

  • Carbamazepine: induces metabolism, reducing contraceptive efficacy.
  • Rifampin: strong enzyme inducer that lowers hormone levels.
  • St. John's wort: herbal inducer that may cause contraceptive failure.

Moderate Interactions (Monitor Closely)

  • Ketoconazole: enzyme inhibitor that can increase hormone concentrations.
  • Selective serotonin reuptake inhibitors (SSRIs): may modestly affect hormone metabolism.

Frequently Asked Questions

Microgyn is a combined oral contraceptive containing ethinylestradiol and levonorgestrel. It is prescribed to prevent unintended pregnancy and can also help regulate menstrual cycles and improve acne associated with hormonal imbalance.

Ethinylestradiol, together with levonorgestrel, suppresses the mid‑cycle surge of luteinizing hormone (LH) and follicle‑stimulating hormone (FSH). This inhibition prevents ovulation, while the progestin component thickens cervical mucus and alters the endometrium, reducing the chance of implantation.

The dosing regimen for Microgyn is determined by the prescribing clinician. Typically, it is taken once daily at the same time for a 21‑day active phase followed by a hormone‑free interval, but the exact schedule should follow the prescriber’s instructions.

Microgyn is contraindicated during pregnancy because it is intended to prevent conception. If pregnancy occurs, the product should be discontinued. Limited data exist for breastfeeding; clinicians usually advise against use while nursing unless the benefits outweigh potential risks.

To order Microgyn, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Microgyn contains the standard estrogen (ethinylestradiol) and a third‑generation progestin (levonorgestrel). Compared with older formulations, it offers similar contraceptive efficacy but may have a different side‑effect profile, such as a slightly lower risk of androgenic effects while maintaining comparable protection against pregnancy.

Microgyn tablets should be stored at room temperature, below 25 °C. Keep them in the original blister pack, protect from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability.

Microgyn is taken orally, usually once each day at the same time. The tablets are swallowed with water and should be started on the first day of the menstrual period or as directed by a healthcare professional.

The most serious risks include venous thromboembolism, stroke, myocardial infarction, and severe allergic reactions such as anaphylaxis. Patients with a history of clotting disorders, smoking, or certain cardiovascular conditions should be evaluated carefully before starting therapy.

Microgyn is contraindicated in women who are pregnant, have known or suspected breast cancer, have a history of thromboembolic disease, uncontrolled hypertension, severe liver disease, or who are smokers over age 35. It should also be avoided in individuals with known hypersensitivity to any component of the tablet.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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