Product image of Microgynon 30 Ed (Ethinylestradiol, Levonorgestrel | Lactose) supplied by GNH India

Microgynon 30 Ed

Active Ingredient:
Ethinylestradiol, Levonorgestrel | Lactose
Origin:
EU

Microgynon 30 Ed (Ethinylestradiol, Levonorgestrel | Lactose)

Ethinylestradiol, the active ingredient in Microgynon 30 Ed, is a synthetic estrogen presented as a combined tablet for oral use. It prevents pregnancy in women of reproductive age when taken as directed.
GNH India supplies Microgynon 30 Ed as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bayer Plc

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Indications & Clinical Uses

  • Microgynon 30 Ed is a combined oral contraceptive that acts on the hormonal regulation of the menstrual cycle.
  • Contraception: provides reliable prevention of pregnancy when taken correctly.
  • Menstrual cycle regulation: helps to regularise bleeding patterns and reduce dysmenorrhoea.
  • Acne management: may improve acne associated with androgen excess.

How It Works

  • Ethinylestradiol and levonorgestrel work together to inhibit the hypothalamic‑pituitary‑ovarian axis. Ethinylestradiol suppresses follicle‑stimulating hormone, while levonorgestrel provides progestogenic activity that prevents ovulation, thickens cervical mucus and alters the endometrium, creating an environment unsuitable for fertilisation and implantation.

Side Effects

Microgynon 30 Ed may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Nausea or gastrointestinal discomfort.
  • Breast tenderness or enlargement.
  • Headache or migraine.
  • Breakthrough or spotting bleeding.
  • Weight fluctuation or fluid retention.
  • Mood changes or irritability.

Serious or Rare Side Effects

  • Venous thromboembolism (deep‑vein thrombosis, pulmonary embolism).
  • Arterial thrombosis (stroke, myocardial infarction).
  • Severe hypertension or hypertensive crisis.
  • Hepatic adenoma or benign liver tumours.
  • Allergic reactions (rash, angio‑edema, anaphylaxis).
  • Visual disturbances or sudden loss of vision.

Precautions & Warnings

  • Before prescribing Microgynon 30 Ed, clinicians should assess individual risk factors and counsel patients on safe use.
  • Assess thrombotic risk: evaluate personal and family history of clotting disorders.
  • Screen for cardiovascular disease: avoid in uncontrolled hypertension or recent myocardial infarction.
  • Consider smoking status: contraindicated in women over 35 who smoke.
  • Review liver function: contraindicated in active liver disease or tumours.
  • Pregnancy and lactation: discontinue if pregnancy is confirmed; advise on breastfeeding considerations.
  • Store at room temperature below 25°C: keep in the original packaging, protect from moisture and heat.

Avoid Interactions

Microgynon 30 Ed can interact with several medicines, altering its effectiveness or safety profile.

Major Interactions (Avoid)

  • Enzyme‑inducing anticonvulsants (e.g., carbamazepine, phenytoin) may reduce contraceptive efficacy.
  • Rifampicin or other potent inducers can lower hormone levels.
  • St. John’s wort herbal supplement may compromise protection.
  • Certain protease inhibitors (e.g., ritonavir) can affect hormone metabolism.
  • Antimicrobial agents such as griseofulvin may diminish effectiveness.

Moderate Interactions (Monitor Closely)

  • Antifungal agents (e.g., ketoconazole) may increase hormone concentrations.
  • SSRIs or SNRIs can heighten bleeding risk.
  • Antihypertensive drugs (e.g., ACE inhibitors) may require dose adjustment.
  • Ginseng or other herbal stimulants may affect hormone balance.
  • Non‑steroidal anti‑inflammatory drugs (NSAIDs) may increase cardiovascular risk when combined.

Frequently Asked Questions

Microgynon 30 Ed is a combined oral contraceptive tablet that is used to prevent pregnancy. It is also prescribed to help regulate menstrual cycles, reduce heavy bleeding, and may improve acne associated with hormonal imbalance.

Ethinylestradiol is a synthetic estrogen that suppresses the release of follicle‑stimulating hormone from the pituitary gland. This inhibition, together with the progestogenic action of levonorgestrel, prevents ovulation and creates cervical mucus that is hostile to sperm, thereby reducing the chance of fertilisation.

The dosing regimen for Microgynon 30 Ed is determined by the prescribing healthcare professional. Typically, the product is taken as a daily tablet in a 21‑day active‑pill sequence followed by a 7‑day hormone‑free interval, but the exact schedule should be confirmed with the prescriber.

Microgynon 30 Ed is contraindicated during pregnancy. If pregnancy occurs, the tablet should be stopped immediately. While limited data exist for breastfeeding, most guidelines advise caution; the prescriber will assess the risk‑benefit ratio for each individual.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Microgynon 30 Ed contains a specific dose of ethinylestradiol and levonorgestrel, offering a balance of estrogen and progestogen that is comparable to other second‑generation combined pills. Its efficacy, side‑effect profile and contraindications are similar, though individual tolerability may vary.

Store Microgynon 30 Ed at room temperature below 25 °C. Keep the tablets in the original blister pack, protect them from moisture, heat and direct sunlight to maintain potency throughout the shelf life.

Microgynon 30 Ed is taken orally, usually once daily at the same time each day. The tablet is swallowed whole with water and should be started on the first day of the menstrual period or as directed by a healthcare professional.

The most serious risks include venous or arterial thromboembolism, severe hypertension, hepatic adenoma, and allergic reactions such as anaphylaxis. Patients should seek immediate medical attention if they experience symptoms like chest pain, sudden shortness of breath, severe headache, or visual changes.

Women with a history of thromboembolic disorders, uncontrolled hypertension, active liver disease, known or suspected breast cancer, or who are pregnant should avoid Microgynon 30 Ed. Additionally, smokers over 35 years of age are contraindicated due to increased cardiovascular risk.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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