Product image of Microgynon (Ethinylestradiol, Levonorgestrel) supplied by GNH India

Microgynon

Active Ingredient:
Ethinylestradiol, Levonorgestrel
Origin:
EU

Microgynon (Ethinylestradiol, Levonorgestrel)

Ethinylestradiol, the active ingredient in Microgynon, is a combined oral contraceptive presented as a 0.03 mg / 0.15 mg oral tablet for oral use. It prevents pregnancy in women of reproductive age by providing hormonal contraception. The formulation also contains levonorgestrel, a progestogenic component that works synergistically to inhibit ovulation and modify cervical mucus.

GNH India supplies Microgynon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for global distribution.

Manufacturer / TM Owner

Jenapharm Gmbh & Co Kg

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Indications & Clinical Uses

Microgynon, a combined oral contraceptive, is indicated for hormonal contraception and related reproductive health conditions.

  • Prevention of pregnancy: provides reliable contraception for women seeking to avoid conception and supports family planning goals.
  • Regulation of menstrual cycle: helps achieve more predictable periods, reduces the duration and volume of menstrual bleeding, and can improve cycle regularity.
  • Management of dysmenorrhea: can lessen menstrual pain associated with primary dysmenorrhea, offering symptomatic relief for many users.

How It Works

  • Microgynon combines ethinylestradiol, a synthetic estrogen, with levonorgestrel, a progestogen. The estrogen component stabilizes the endometrial lining, while the progestogen suppresses the mid‑cycle luteinizing hormone surge, preventing ovulation. Together they thicken cervical mucus and alter the endometrial environment, creating conditions unfavorable for fertilization and implantation. These hormonal actions are sustained throughout the 21‑day active phase of the tablet regimen, ensuring continuous contraceptive effect.

Side Effects

Microgynon may be associated with a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Nausea
  • Breast tenderness
  • Headache
  • Spotting between periods

Serious or Rare Side Effects

  • Deep vein thrombosis
  • Pulmonary embolism
  • Severe liver dysfunction
  • Anaphylactic reaction

Precautions & Warnings

When prescribing Microgynon, clinicians should consider several safety measures.

  • Assess cardiovascular risk: evaluate personal or family history of thromboembolic events before prescribing.
  • Review smoking status: avoid use in women over 35 who smoke cigarettes.
  • Check hepatic function: use with caution in patients with liver disease or abnormal liver enzymes.
  • Monitor blood pressure: measure regularly, especially in patients with hypertension.
  • Counsel on missed tablets: advise prompt action to maintain contraceptive efficacy.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture.

Avoid Interactions

Microgynon can interact with other medicines, requiring attention to potential changes in effectiveness or safety.

Major Interactions (Avoid)

  • Potent CYP3A4 inducers (e.g., rifampicin, carbamazepine): may reduce contraceptive effectiveness.
  • Antiretroviral protease inhibitors (e.g., ritonavir): may increase hormone levels and risk of side effects.
  • St. John’s wort: may markedly decrease efficacy.

Moderate Interactions (Monitor Closely)

  • Antifungal agents (e.g., fluconazole): may increase plasma hormone concentrations.
  • Certain antibiotics (e.g., tetracycline, metronidazole): may slightly reduce effectiveness.
  • SSRIs (e.g., fluoxetine): may increase risk of bleeding.

Frequently Asked Questions

Microgynon is a combined oral contraceptive indicated primarily for the prevention of pregnancy. It is also prescribed to help regulate menstrual cycles and to alleviate symptoms of dysmenorrhea, providing a reliable hormonal method for family planning and menstrual management.

Ethinylestradiol is a synthetic estrogen that stabilizes the endometrial lining and works with levonorgestrel to suppress the mid‑cycle luteinizing hormone surge. This inhibition prevents ovulation, while also contributing to thickened cervical mucus and an altered uterine environment that together reduce the chance of fertilization and implantation.

The dosing regimen for Microgynon is determined by the prescribing healthcare professional. Typically, the product is taken as a daily oral tablet according to a 21‑day active‑tablet schedule followed by a 7‑day pill‑free interval, but the exact plan should be confirmed with the prescriber.

Microgynon is classified as Pregnancy Category X, meaning it is contraindicated during pregnancy because it may harm the fetus. It is also not recommended for breastfeeding women, as hormonal exposure can affect milk production and infant development. Alternative contraception should be discussed with a healthcare provider.

To order Microgynon, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Microgynon contains a low‑dose estrogen (0.03 mg) combined with levonorgestrel, a widely used progestogen. Compared with higher‑dose formulations, it may have a slightly lower risk of estrogen‑related side effects while maintaining effective ovulation suppression. Its safety and efficacy profile is comparable to other second‑generation combined pills.

Microgynon tablets should be stored at ambient temperature, preferably below 25 °C. Keep them in the original blister pack, protect from moisture and direct sunlight, and keep out of reach of children. Do not store in bathrooms or other humid environments.

Microgynon is taken orally, once daily, at the same time each day. Tablets can be swallowed with or without food. After a 21‑day course of active tablets, a 7‑day pill‑free interval follows, during which withdrawal bleeding typically occurs.

The most serious risks include venous thromboembolism (deep‑vein thrombosis and pulmonary embolism), arterial events such as stroke or myocardial infarction, severe liver dysfunction, and rare allergic reactions like anaphylaxis. Women with a history of clotting disorders, smoking over age 35, or certain cardiovascular conditions should avoid use.

Microgynon is contraindicated in women who are pregnant, have known or suspected breast cancer, have a history of thromboembolic disorders, uncontrolled hypertension, severe liver disease, or are smokers over 35 years of age. It should also be avoided in individuals with known hypersensitivity to any component of the tablet.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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