Microlax (Sodium Citrate, Sodium Lauryl Sulfoacetate)

Microlax acts locally in the lower gastrointestinal tract to relieve constipation and to clear the bowel before procedures.

• Occasional constipation: provides rapid softening and evacuation of stool.
• Facilitation of bowel movements: assists patients who need a quick, gentle bowel emptying.
• Preparation for diagnostic procedures: clears the rectum and sigmoid colon before colonoscopy, sigmoidoscopy or radiographic studies.

• Microlax creates an osmotic gradient by drawing water into the intestinal lumen through the action of sodium citrate, while sodium lauryl sulfoacetate acts as a surfactant that irritates the rectal mucosa. This dual action softens stool and stimulates peristalsis, resulting in a rapid and gentle evacuation of fecal material.

Microlax may cause a range of mild to serious reactions.

Common Side Effects

• Mild abdominal cramping: transient discomfort in the lower abdomen.
• Rectal irritation: mild burning or itching at the site of administration.
• Loose stools or mild diarrhea: rapid transit of softened stool.
• Nausea: occasional feeling of queasiness after use.
• Flatulence: increased gas production.
• Transient urgency: sudden need to defecate.

Serious or Rare Side Effects

• Severe rectal bleeding: unexpected bleeding that requires medical attention.
• Allergic reaction: rash, swelling, or difficulty breathing.
• Electrolyte imbalance: rare shifts in sodium or potassium levels.
• Severe abdominal pain: persistent or worsening pain.
• Colonic perforation: extremely rare but serious injury to the bowel wall.

Before using Microlax, consider the following safety measures.

• Follow label instructions: use only the recommended amount.
• Not for chronic constipation: avoid regular long‑term use without medical advice.
• Avoid if rectal bleeding of unknown cause: consult a physician first.
• Caution in inflammatory bowel disease: may exacerbate symptoms during flare.
• Monitor electrolyte disorders: patients with known imbalances should use under supervision.
• Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Microlax can interact with other medicines, requiring attention to avoid reduced efficacy or increased risk.

Major Interactions (Avoid)

• Concurrent strong laxatives: may cause excessive fluid loss and electrolyte disturbance.
• Antidiarrheal agents (e.g., loperamide): can counteract the intended effect.
• Oral electrolyte solutions: combined use may lead to imbalance.

Moderate Interactions (Monitor Closely)

• Anticoagulants: increased risk of rectal bleeding.
• Cardiac glycosides: potential electrolyte shifts affecting drug levels.
• Diuretics: may enhance sodium loss and affect fluid balance.