Product image of Microlax (Sodium Citrate, Sorbitol (E420), Sodium Lauryl Sulfoacetate) supplied by GNH India

Microlax

Active Ingredient:
Sodium Citrate, Sorbitol (E420), Sodium Lauryl Sulfoacetate
Origin:
EU

Microlax (Sodium Citrate, Sorbitol (E420), Sodium Lauryl Sulfoacetate)

Sodium citrate, the active ingredient in Microlax, is a laxative presented as an enema solution for rectal use. It helps relieve occasional constipation and is employed to cleanse the bowel before certain medical examinations or procedures. The formulation also contains sorbitol and sodium lauryl sulfoacetate, which together create an osmotic gradient and mild mucosal irritation to promote stool passage.

GNH India supplies Microlax as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution.

Manufacturer / TM Owner

Mcneil Ab

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Indications & Clinical Uses

Microlax, an osmotic laxative, is indicated for conditions that require softening of stool or cleansing of the distal colon.

  • Occasional constipation: provides rapid softening of stool, increases water content, and stimulates peristalsis for prompt evacuation.
  • Bowel preparation before diagnostic procedures: effectively cleanses the rectum and distal colon, facilitating clear imaging or endoscopic access.
  • Post‑operative constipation: assists in restoring regular bowel movements after surgery when mobility is reduced.
  • Constipation associated with limited mobility: offers quick relief for bedridden or immobile patients by promoting stool passage without systemic absorption.

How It Works

  • Microlax works by creating an osmotic gradient in the colon. Sodium citrate and sorbitol draw water into the intestinal lumen, while sodium lauryl sulfoacetate irritates the rectal mucosa. The increased fluid softens the stool and the mild irritation stimulates peristaltic activity, resulting in rapid evacuation of fecal material. The combined action produces a localized laxative effect without significant systemic absorption, making it suitable for short‑term use.

Side Effects

Microlax may cause local and systemic reactions, most of which are mild and transient.

Common Side Effects

  • Rectal irritation: mild burning or discomfort at the application site.
  • Abdominal cramping: brief spasms after administration.
  • Urgency to defecate: sudden need to evacuate stool.
  • Watery discharge: excess fluid may be expelled.
  • Nausea: mild queasiness after enema.
  • Dizziness: transient light‑headedness post‑administration.

Serious or Rare Side Effects

  • Severe abdominal pain: intense pain requiring medical attention.
  • Rectal bleeding: unexpected bleeding from the rectal mucosa.
  • Allergic reaction: rash, itching, swelling, or difficulty breathing.
  • Electrolyte imbalance: rare disturbance due to excessive fluid loss.

Precautions & Warnings

When using Microlax, consider the following precautions to ensure safe and effective use.

  • Pregnancy: consult a healthcare professional before use, as safety data are limited.
  • Breastfeeding: use only if the benefit outweighs potential risk to the infant.
  • Bowel obstruction: avoid use in patients with known intestinal blockage.
  • Inflammatory bowel disease flare: exercise caution during active ulcerative colitis or Crohn’s disease.
  • Electrolyte disorders: monitor patients prone to electrolyte imbalance, especially with repeated use.
  • Store at ambient temperature: keep the container tightly closed, protect from moisture and direct sunlight.

Avoid Interactions

Microlax can interact with certain medications or substances, affecting efficacy or safety.

Major Interactions (Avoid)

  • Lithium therapy: altered renal handling may increase lithium levels, risking toxicity.
  • Oral rehydration salts: combined use can lead to excessive electrolyte shifts.

Moderate Interactions (Monitor Closely)

  • Diuretics: concurrent use may exacerbate electrolyte loss.
  • Other laxatives (stimulant or osmotic): risk of severe dehydration or electrolyte imbalance.
  • Antacids containing magnesium or aluminum: may reduce the laxative effect of Microlax.

Frequently Asked Questions

Microlax is an over‑the-counter rectal enema that provides rapid relief from occasional constipation and is also employed to cleanse the rectum and distal colon before diagnostic or therapeutic procedures such as colonoscopy, sigmoidoscopy, or surgery. Its osmotic action softens stool and stimulates a gentle bowel movement, making it useful for short‑term bowel preparation.

Sodium citrate, together with sorbitol and sodium lauryl sulfoacetate, creates an osmotic gradient that draws water into the colon. The increased fluid softens the fecal mass, while the surfactant irritates the rectal lining, prompting peristaltic contractions. This combined effect facilitates quick evacuation of stool without significant systemic absorption.

The appropriate dose of Microlax is determined by the prescribing healthcare professional based on the patient’s age, condition, and clinical need. Typically a single enema is administered rectally, and the patient is advised to retain the solution for a short period to allow the laxative effect. Repeat dosing should follow medical guidance.

Safety data for Microlax in pregnancy and lactation are limited. It should be used only if the potential benefit justifies any possible risk to the fetus or infant, and this decision must be made by a qualified healthcare provider. Women who are pregnant or nursing should discuss alternative options and obtain professional advice before use.

To place an order, submit an enquiry on the Microlax product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the sales team provides pricing, availability, shipping details—including any temperature requirements—and assists with import documentation.

Compared with oral stimulant laxatives, Microlax acts locally in the rectum, producing a faster onset of action and fewer systemic side effects. Unlike bulk‑forming agents, it does not require dietary fiber intake. Its osmotic mechanism is similar to other rectal enemas, but the inclusion of a surfactant offers additional mucosal stimulation, making it particularly effective for rapid bowel cleansing.

Microlax should be stored at ambient temperature, preferably below 25 °C, in its original sealed container. Protect the product from moisture, direct sunlight, and extreme temperature fluctuations. Keep out of reach of children and do not use the solution after the expiration date printed on the packaging.

Microlax is administered rectally as a single‑dose enema. The patient lies on their side with knees drawn toward the chest, inserts the applicator tip gently into the rectum, and releases the solution. After administration, the patient should remain in the same position for a few minutes to allow the enema to work, then proceed to the toilet to evacuate the bowels.

The most serious risks include severe abdominal pain, rectal bleeding, and rare allergic reactions such as rash, swelling, or difficulty breathing. In patients with electrolyte disorders, excessive fluid loss may lead to imbalance. Anyone experiencing intense pain, persistent bleeding, or signs of an allergic response should seek immediate medical attention.

Microlax is contraindicated in individuals with known or suspected intestinal obstruction, severe inflammatory bowel disease flare, or hypersensitivity to any of its ingredients. It should also be avoided in patients with significant electrolyte disturbances unless supervised by a clinician. Children, the elderly, and pregnant or breastfeeding women should use the product only under medical advice.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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