Microlax (Sorbitol, Liquid (Crystallising), Sodium Citrate, Sodium Lauryl Sulfoacetate 70%)

• Microlax, an osmotic laxative administered rectally, is used for conditions that require rapid bowel evacuation.
• Occasional constipation: provides prompt softening of stool, increases water content in the colon, and facilitates natural evacuation without the need for oral laxatives.
• Fecal impaction: helps break down hardened stool, reduces stool bulk, and promotes clearance of the colon, making manual removal easier if required.
• Pre‑procedure bowel cleansing: prepares the bowel for diagnostic or surgical procedures by emptying the rectum, reducing residual stool that could interfere with imaging or operative fields.

• Microlax works by creating an osmotic gradient in the colon through its sorbitol and sodium citrate components, which draw water into the intestinal lumen. The sodium lauryl sulfoacetate acts as a surfactant, reducing surface tension and stimulating peristaltic activity. The combined effect softens stool, increases intraluminal volume, and promotes rapid evacuation of fecal material. This localized action occurs within minutes after rectal administration, providing prompt relief without systemic absorption.

Microlax may cause local or systemic reactions, most of which are mild and transient.

Common Side Effects

• Mild rectal irritation: slight burning or discomfort at the site of administration.
• Cramping: transient abdominal or rectal cramping after enema.
• Loose stools: temporary increase in stool liquidity.
• Nausea: mild feeling of nausea in some users.

Serious or Rare Side Effects

• Severe allergic reaction: rash, itching, swelling, or difficulty breathing.
• Persistent diarrhea: prolonged watery stools leading to dehydration.
• Electrolyte imbalance: rare shifts in sodium or potassium levels with excessive use.
• Rectal bleeding: unusual bleeding that persists beyond the immediate effect.

Before using Microlax, consider the following precautions to ensure safe and effective use.

• Age restrictions: not recommended for infants under 2 years without medical advice.
• Existing bowel conditions: avoid if you have inflammatory bowel disease, ulcerative colitis, or recent bowel surgery unless directed by a physician.
• Medication interactions: inform your doctor of any oral or rectal medications, especially those affecting electrolyte balance.
• Frequency of use: limit to occasional use; chronic reliance may lead to dependence or electrolyte disturbances.
• Allergies: discontinue if you experience signs of hypersensitivity such as rash or swelling.
• Store at ambient temperature: keep below 25 °C, protect from moisture and direct sunlight, and retain in the original container.

Microlax can interact with certain medicines or conditions; awareness of these interactions helps prevent adverse outcomes.

Major Interactions (Avoid)

• Potassium-sparing diuretics: concurrent use may increase risk of hyperkalemia due to altered electrolyte balance.
• Oral laxatives: combined use can cause excessive fluid loss and severe diarrhea.

Moderate Interactions (Monitor Closely)

• Antacids containing magnesium: may enhance osmotic effect and lead to dehydration.
• Anticholinergic agents: could reduce the stimulant effect of the surfactant component.
• Chronic corticosteroid therapy: may increase susceptibility to electrolyte disturbances when used repeatedly.