Microlax (Sorbitol, Liquid (Crystallising), Sodium Citrate, Sodium Lauryl Sulfoacetate 70%)

Microlax is an osmotic laxative used to treat conditions affecting bowel movement.

• Constipation: softens stool and promotes evacuation in patients with occasional or chronic constipation.
• Fecal impaction: facilitates relief of hardened stool in impaction cases.
• Pre‑operative bowel cleansing: clears the lower bowel before surgical or diagnostic procedures.

• Microlax works by combining an osmotic agent (sorbitol) with sodium citrate and a surfactant (sodium lauryl sulfoacetate). The osmotic agents draw water into the colon, increasing stool fluidity, while the surfactant reduces surface tension, allowing easier passage of softened stool through the rectum. The resulting increase in intraluminal volume stimulates peristaltic activity, promoting rapid evacuation within minutes after administration. This local action provides prompt relief without systemic absorption.

Microlax may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

• Mild rectal irritation: slight burning or discomfort at the application site.
• Cramping: transient abdominal or rectal cramps.
• Diarrhea: loose stools occurring shortly after use.
• Nausea: occasional feeling of nausea.
• Flatulence: increased gas production.
• Fecal urgency: sudden need to defecate.

Serious or Rare Side Effects

• Severe allergic reaction: rash, swelling, or difficulty breathing.
• Persistent rectal bleeding: ongoing bleeding after administration.
• Electrolyte imbalance: rare disturbance due to excessive fluid loss.
• Severe abdominal pain: intense pain requiring medical attention.
• Syncope: fainting episodes.
• Severe rectal ulceration: ulcer formation at the site of administration.

When using Microlax, certain precautions should be observed to ensure safe and effective use.

• Age restriction: not recommended for infants under 2 years without medical advice.
• Underlying disease: avoid in patients with inflammatory bowel disease flare-ups.
• Medication interaction: consult a physician if using other laxatives or antidiarrheal agents.
• Fluid balance: monitor for dehydration in patients with chronic diarrhea.
• Allergies: discontinue if signs of hypersensitivity occur.
• Store at room temperature: keep in original container, protect from light and moisture.

Microlax can interact with other medicines, affecting their efficacy or safety.

Major Interactions (Avoid)

• Oral electrolyte solutions: may cause excessive fluid shifts when combined.
• Strong antidiarrheal drugs (e.g., loperamide): can reduce intended laxative effect.
• Certain antibiotics (e.g., quinolones): altered absorption if bowel motility is significantly changed.

Moderate Interactions (Monitor Closely)

• Other rectal preparations: risk of additive irritation.
• Anticoagulants: monitor for increased risk of bleeding if rectal mucosa is damaged.
• Diuretics: watch for potential dehydration.