Product image of Mictonorm Xl 30 Mg (Propiverine Hydrochloride) supplied by GNH India

Mictonorm Xl 30 Mg

Active Ingredient:
Propiverine Hydrochloride
Origin:
EU

Mictonorm Xl 30 Mg (Propiverine Hydrochloride)

Propiverine hydrochloride, the active ingredient in Mictonorm XL 30 mg, is an antimuscarinic presented as a 30 mg extended-release tablet for oral use. It treats overactive bladder, urge urinary incontinence and mixed urinary incontinence in adults.

GNH India supplies Mictonorm XL 30 mg as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Herbacos Recordati S.R.O.

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Indications & Clinical Uses

Propiverine hydrochloride is an antimuscarinic used to manage symptoms of overactive bladder and related urinary disorders.

  • Overactive bladder: reduces urgency, frequency and nocturia.
  • Urge urinary incontinence: decreases episodes of involuntary leakage.
  • Mixed urinary incontinence: improves overall bladder control.

How It Works

  • Propiverine hydrochloride acts as a competitive antagonist of muscarinic M3 receptors located on the detrusor muscle of the urinary bladder. By blocking these receptors, it diminishes involuntary bladder contractions, thereby increasing bladder capacity and reducing urgency and frequency of urination.

Side Effects

Common Side Effects

  • Dry mouth
  • Constipation
  • Blurred vision
  • Headache

Serious or Rare Side Effects

  • Acute urinary retention requiring catheterisation
  • Severe allergic reaction (anaphylaxis)
  • Angle‑closure glaucoma

Precautions & Warnings

Precautions should be taken when prescribing propiverine to ensure patient safety.

  • Renal impairment: assess renal function and adjust therapy if needed.
  • Hepatic impairment: use with caution and monitor liver enzymes.
  • History of urinary retention: monitor closely for worsening symptoms.
  • Narrow‑angle glaucoma: avoid use in patients with this condition.
  • Pregnancy and lactation: safety not established; avoid unless essential.
  • Store at ambient temperature: keep below 25°C, retain original packaging, protect from moisture.

Avoid Interactions

Propiverine may interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Strong anticholinergic agents: additive anticholinergic load may increase side effects.
  • CYP3A4 inhibitors (e.g., ketoconazole, erythromycin): may raise propiverine plasma concentrations.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inducers (e.g., rifampicin, carbamazepine): may reduce therapeutic effect.
  • Other bladder antimuscarinics: increased risk of urinary retention.
  • Drugs that prolong QT interval: monitor cardiac rhythm.

Frequently Asked Questions

Mictonorm XL 30 mg contains propiverine hydrochloride and is prescribed to manage symptoms of overactive bladder, urge urinary incontinence and mixed urinary incontinence. It helps reduce urinary urgency, frequency and episodes of involuntary leakage in adult patients.

Propiverine works by competitively blocking muscarinic M3 receptors in the detrusor muscle of the bladder. This antagonism reduces involuntary muscle contractions, allowing the bladder to hold more urine and decreasing the urgency and frequency of voiding.

The prescribed dose of Mictonorm XL 30 mg is determined by the treating physician based on the individual’s clinical condition and response. While many clinicians start with one 30 mg extended‑release tablet taken once daily, the exact regimen should be confirmed with a healthcare professional.

Safety of propiverine during pregnancy and lactation has not been established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.

To order Mictonorm XL 30 mg, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Mictonorm XL (propiverine) offers a once‑daily extended‑release formulation, which can improve adherence compared with multiple‑daily‑dose agents such as oxybutynin. Propiverine also has a slightly different receptor affinity profile, potentially resulting in a lower incidence of dry mouth for some patients, though individual response varies.

Mictonorm XL tablets should be stored at ambient temperature, below 25 °C, in the original blister pack to protect from moisture and light. Keep the medication out of reach of children and do not use after the expiry date printed on the packaging.

Mictonorm XL is taken orally as a whole extended‑release tablet. Swallow the tablet whole with a glass of water; do not split, chew, or crush it, as this may affect the controlled release of the active ingredient.

Serious risks include acute urinary retention that may require catheterisation, severe allergic reactions such as anaphylaxis, and angle‑closure glaucoma, which can lead to vision loss. Patients should seek immediate medical attention if they experience sudden inability to urinate, severe eye pain, or signs of an allergic reaction.

Mictonorm XL should be avoided in patients with known hypersensitivity to propiverine or any excipients, those with uncontrolled narrow‑angle glaucoma, significant urinary retention, or severe hepatic impairment. It is also contraindicated in individuals where anticholinergic therapy is medically prohibited.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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