Product image of Midazolam B. Braun (Midazolam Hydrochloride) supplied by GNH India

Midazolam B. Braun

Active Ingredient:
Midazolam Hydrochloride
Origin:
EU

Midazolam B. Braun (Midazolam Hydrochloride)

Midazolam, the active ingredient in Midazolam B. Braun, is a benzodiazepine presented as a sterile injectable solution for intramuscular, intravenous, or rectal use. It is employed to produce rapid sedation, anxiolysis, and seizure control in adult and pediatric patients undergoing procedures or experiencing acute seizures.
GNH India supplies Midazolam B. Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

B.Braun Melsungen Ag

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Midazolam is a benzodiazepine that provides central nervous system depression for several clinical situations.
  • Procedural sedation: enables safe, rapid‑onset sedation for diagnostic or therapeutic procedures.
  • Pre‑operative anxiolysis: reduces anxiety and facilitates induction of anesthesia before surgery.
  • Induction of anesthesia: provides a short‑acting hypnotic effect to initiate general anesthesia.
  • Status epilepticus: terminates prolonged seizures when other agents are ineffective.
  • Acute seizure control: rapidly aborts breakthrough seizures in emergency settings.

How It Works

  • Midazolam acts as a positive allosteric modulator of the GABA‑A receptor complex. By binding to a distinct site on the receptor, it enhances the affinity of GABA for its channel, increasing chloride ion influx and hyperpolarizing neuronal membranes, which results in central nervous system depression and the clinical effects of sedation, anxiolysis, hypnosis, and anticonvulsant activity.

Side Effects

Midazolam may cause a range of adverse reactions, from mild to life‑threatening.

Common Side Effects

  • Drowsiness or fatigue
  • Mild hypotension
  • Nausea or vomiting
  • Headache

Serious or Rare Side Effects

  • Severe respiratory depression
  • Anaphylactic reaction
  • Cardiac arrhythmias
  • Paradoxical agitation or aggression

Precautions & Warnings

  • When using Midazolam, clinicians should consider several safety measures.
  • Dose adjustment in elderly: reduce dose due to increased sensitivity.
  • Avoid in severe respiratory insufficiency: risk of profound respiratory depression.
  • Caution with hepatic impairment: prolonged elimination may occur.
  • Concurrent CNS depressants: monitor for additive sedation and respiratory effects.
  • Pregnancy and lactation: use only if potential benefit justifies potential risk.
  • Store at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Midazolam interacts with several drug classes that can modify its effects.

Major Interactions (Avoid)

  • Opioids: synergistic respiratory depression.
  • Barbiturates: enhanced central nervous system depression.
  • CYP3A4 inhibitors (e.g., ketoconazole): increased plasma concentrations.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inducers (e.g., rifampin): reduced efficacy.
  • Anticonvulsants (e.g., phenytoin): lowered plasma levels.
  • Antidepressants (e.g., fluoxetine): increased sedation risk.

Frequently Asked Questions

Midazolam B. Braun is a benzodiazepine used for procedural sedation, pre‑operative anxiolysis, induction of anesthesia, and the rapid control of seizures such as status epilepticus. It provides short‑acting central nervous system depression to facilitate safe medical procedures and emergency seizure management.

Midazolam enhances the activity of the inhibitory neurotransmitter GABA at the GABA‑A receptor. By increasing chloride ion influx into neurons, it hyperpolarizes the cell membrane, leading to reduced neuronal excitability and producing sedation, anxiolysis, hypnosis, and anticonvulsant effects.

The specific dose of Midazolam B. Braun is determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and route of administration. Healthcare professionals tailor the regimen to achieve the desired level of sedation or seizure control while monitoring safety.

Midazolam’s safety in pregnancy and lactation is not well established. It should be used only when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To order Midazolam B. Braun, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Midazolam has a rapid onset and short duration of action compared with many benzodiazepines such as diazepam or lorazepam. This makes it especially suitable for procedural sedation and acute seizure control, whereas longer‑acting agents are often preferred for chronic anxiety or insomnia.

Midazolam B. Braun should be stored at room temperature, below 25 °C, in its original packaging. Protect the product from excessive light, moisture, and physical damage. Do not freeze or refrigerate unless the label specifically indicates a cold‑chain requirement.

Midazolam B. Braun is administered by a healthcare professional via intramuscular, intravenous, or rectal routes, depending on the clinical situation. The route, dose, and rate of administration are selected by the prescriber to achieve the intended level of sedation or seizure control.

The most serious risks include severe respiratory depression, profound hypotension, anaphylaxis, and paradoxical reactions such as agitation or aggression. Continuous monitoring of respiratory and cardiovascular status is essential, especially when higher doses or concurrent depressant drugs are used.

Midazolam B. Braun is contraindicated in patients with known hypersensitivity to midazolam or any benzodiazepine component, and it should be avoided in individuals with severe respiratory insufficiency, acute narrow‑angle glaucoma, or those taking certain interacting medications without appropriate monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.