Product image of Midazolam B. Braun (Midazolam Hydrochloride) supplied by GNH India

Midazolam B. Braun

Active Ingredient:
Midazolam Hydrochloride
Origin:
EU

Midazolam B. Braun (Midazolam Hydrochloride)

Midazolam Hydrochloride, the active ingredient in Midazolam B. Braun, is a benzodiazepine presented as a sterile injectable solution for intramuscular, intravenous, and rectal use. It provides rapid sedation, anxiolysis, anticonvulsant effects, and serves as an adjunct in anesthesia for patients requiring procedural sedation or seizure control.

GNH India supplies Midazolam B. Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide, ensuring quality‑assured products and reliable logistics across multiple regions, with comprehensive regulatory support and dedicated customer service.

Manufacturer / TM Owner

B.Braun Melsungen Ag

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Midazolam is a benzodiazepine that modulates GABA‑A receptors, making it useful in several sedation‑related and seizure‑related clinical scenarios.

  • Procedural sedation: provides rapid, controllable sedation for diagnostic or therapeutic procedures.
  • Induction of anesthesia: facilitates smooth induction and reduces anesthetic requirements.
  • Pre‑operative anxiolysis: eases patient anxiety before surgery.
  • Status epilepticus: terminates ongoing seizures when other agents are ineffective.
  • Acute seizure control: offers rapid anticonvulsant action in emergency settings.

How It Works

  • Midazolam Hydrochloride acts as a positive allosteric modulator of the GABA‑A receptor complex. By binding to a distinct site, it enhances the affinity of GABA for its receptor, increasing chloride ion influx, hyperpolarizing neuronal membranes, and thereby amplifying inhibitory neurotransmission that produces sedation, anxiolysis, muscle relaxation, and anticonvulsant effects.

Side Effects

Midazolam may cause a range of adverse reactions that vary in frequency and severity.

Common Side Effects

  • Drowsiness
  • Dizziness
  • Amnesia
  • Nausea

Serious or Rare Side Effects

  • Severe respiratory depression
  • Anaphylactic reaction
  • Paradoxical agitation

Precautions & Warnings

When using Midazolam, clinicians should observe several safety measures.

  • Dose titration: adjust to clinical response and individual patient factors.
  • Respiratory monitoring: continuous observation is required, especially in high‑risk patients.
  • Concomitant CNS depressants: avoid or use with caution due to additive effects.
  • Elderly patients: initiate therapy at lower doses because of increased sensitivity.
  • Pregnancy and lactation: consider only if potential benefits justify potential risks.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze.

Avoid Interactions

Midazolam interacts with several drug classes; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Opioids: additive respiratory depression.
  • Barbiturates: enhanced central nervous system depression.
  • Alcohol: increased sedation and respiratory compromise.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inducers (e.g., rifampin): may reduce midazolam effectiveness.
  • Antifungal agents (e.g., ketoconazole): can raise midazolam plasma concentrations.

Frequently Asked Questions

Midazolam B. Braun is a benzodiazepine formulation used primarily for procedural sedation, induction of anesthesia, pre‑operative anxiolysis, and the rapid control of seizures such as status epilepticus. It is administered by intramuscular, intravenous, or rectal routes depending on the clinical situation.

Midazolam Hydrochloride enhances the activity of the neurotransmitter GABA at the GABA‑A receptor. By increasing chloride ion flow into neurons, it hyperpolarizes the cell membrane, leading to reduced neuronal excitability and producing sedation, anxiolysis, muscle relaxation, and anticonvulsant effects.

The specific dose of Midazolam B. Braun is determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and route of administration. Healthcare professionals adjust the dose to achieve the desired level of sedation or seizure control while monitoring safety.

Safety data for Midazolam during pregnancy and lactation are limited. It should only be used when the potential therapeutic benefit justifies any potential risk to the fetus or infant. Clinicians must evaluate each case individually and discuss risks with the patient.

To order Midazolam B. Braun, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and required import documentation.

Midazolam has a rapid onset and short duration compared with agents such as diazepam or lorazepam, making it especially useful for procedural sedation and acute seizure control. Its water‑soluble formulation allows intravenous use, whereas some alternatives are only available in oral or intramuscular forms.

Midazolam B. Braun should be stored at 2‑8 °C in a refrigerator, protected from light, and must not be frozen or shaken. Keep the product in its original packaging until use to maintain stability and potency.

The drug can be given intramuscularly, intravenously, or rectally, depending on the clinical indication. Intravenous administration provides the fastest onset, while intramuscular and rectal routes are used when IV access is not available or for specific procedural protocols.

The most serious risks include severe respiratory depression, which may require assisted ventilation, anaphylactic reactions, and paradoxical agitation or aggression. Prompt monitoring of respiratory function and readiness to intervene are essential during and after administration.

Midazolam B. Braun is contraindicated in patients with known hypersensitivity to midazolam or any component of the formulation, severe respiratory insufficiency, acute narrow‑angle glaucoma, and in individuals who have had a severe adverse reaction to other benzodiazepines.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.