Product image of Migard (Frovatriptan) supplied by GNH India

Migard

Active Ingredient:
Frovatriptan
Origin:
EU

Migard (Frovatriptan)

Frovatriptan, the active ingredient in Migard, is a Triptan presented as a 2.5 mg tablet for oral use. It is classified as an antimigraine agent (ATC code N02CC04) and is indicated for the acute treatment of migraine attacks, including migraine with aura, in adult patients.

GNH India supplies Migard as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and regulatory requirements across EU and global markets.

Manufacturer / TM Owner

Menarini International Operations Luxembourg S.A.

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Indications & Clinical Uses

Frovatriptan acts on the migraine pathway as a selective 5‑HT1B/1D receptor agonist.

  • Acute migraine attack: provides rapid relief of headache and associated symptoms.
  • Migraine with aura: reduces headache severity when aura precedes the attack.
  • Menstrual migraine (short‑term prevention): may be used to lessen migraine frequency around menstruation.

How It Works

  • Frovatriptan selectively stimulates serotonin 5‑HT1B and 5‑HT1D receptors on intracranial blood vessels and trigeminal nerve endings. Activation of 5‑HT1B receptors induces cranial vasoconstriction, while 5‑HT1D stimulation inhibits release of vasoactive neuropeptides such as CGRP, thereby aborting the migraine cascade.

Side Effects

Common Side Effects

  • Nausea: mild to moderate gastrointestinal upset.
  • Dizziness: transient light‑headedness.
  • Fatigue: feeling of tiredness or weakness.
  • Dry mouth: reduced salivation.
  • Somnolence: mild sleepiness.
  • Chest discomfort: mild pressure or tightness.

Serious or Rare Side Effects

  • Coronary vasospasm: severe chest pain requiring medical attention.
  • Myocardial infarction: heart attack symptoms.
  • Serotonin syndrome: agitation, hyperthermia, tremor.
  • Severe hypertension: sudden high blood pressure.
  • Allergic reactions: rash, swelling, anaphylaxis.
  • Cardiac arrhythmias: irregular heart rhythm.

Precautions & Warnings

Before using Migard, consider the following precautions:

  • Cardiovascular disease: avoid if you have coronary artery disease, angina, or uncontrolled hypertension.
  • History of stroke or TIA: contraindicated in patients with prior cerebrovascular events.
  • Concomitant triptans or ergotamines: do not combine with other migraine-specific agents.
  • Pregnancy Category C: discuss risks with a healthcare professional before use.
  • Hepatic impairment: use with caution; dose adjustment may be required.
  • Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Frovatriptan may interact with several medicines.

Major Interactions (Avoid)

  • MAO inhibitors: increase risk of serotonin syndrome.
  • SSRIs/SNRIs: combined use can precipitate serotonin toxicity.
  • Other triptans or ergot alkaloids: additive vasoconstrictive effects.
  • Strong CYP3A4 inhibitors: may raise frovatriptan plasma levels.

Moderate Interactions (Monitor Closely)

  • NSAIDs: concurrent use may raise risk of gastrointestinal bleeding.
  • Antihypertensives: may reduce blood‑pressure‑lowering efficacy.
  • Oral contraceptives: may influence migraine frequency; monitor symptom changes.

Frequently Asked Questions

Migard contains frovatriptan, a prescription‑only triptan indicated for the acute treatment of migraine attacks, including migraine with aura, in adult patients.

Frovatriptan selectively activates serotonin 5‑HT1B and 5‑HT1D receptors, causing cranial blood‑vessel constriction and blocking release of pain‑triggering neuropeptides, which helps stop a migraine once it has started.

The prescribed dose of Migard is determined by the treating physician based on individual clinical assessment and local prescribing guidelines.

Migard is classified as Pregnancy Category C, meaning risk cannot be ruled out. Use only if the potential benefit justifies the risk, and discuss breastfeeding considerations with a healthcare professional.

Submit an enquiry on the Migard product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.

Migard (frovatriptan) has a longer half‑life than many other triptans, offering sustained migraine relief and a lower recurrence rate, while maintaining a safety profile comparable to other agents in the class.

Store Migard tablets below 25 °C in the original container, protected from moisture and direct sunlight. Keep out of reach of children.

Migard is taken orally as a single tablet at the onset of a migraine attack. Swallow the tablet whole with water; do not crush or chew.

Serious risks include coronary vasospasm, myocardial infarction, severe hypertension, serotonin syndrome, and rare allergic reactions such as anaphylaxis. Seek immediate medical attention if these occur.

Migard should not be used by patients with uncontrolled cardiovascular disease, a history of stroke or transient ischemic attack, severe hepatic impairment, or those taking other triptans, ergotamines, or MAO inhibitors.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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