Product image of Migraine Pain Relief (Ibuprofen Lysine) supplied by GNH India

Migraine Pain Relief

Active Ingredient:
Ibuprofen Lysine
Origin:
EU

Migraine Pain Relief (Ibuprofen Lysine)

Ibuprofen, the active ingredient in Migraine Pain Relief, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It is used to treat migraine and other headache disorders in adults.
GNH India supplies Migraine Pain Relief as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Manufacturer / TM Owner

Wrafton Laboratories Limited

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Indications & Clinical Uses

Ibuprofen acts as an analgesic and anti‑inflammatory agent for common headache disorders.

  • Migraine: provides relief from migraine attacks by reducing pain and associated inflammation.
  • Tension‑type headache: eases pressure‑type head pain through anti‑inflammatory action.
  • General headache: lowers discomfort from various headache causes by inhibiting prostaglandin synthesis.

How It Works

  • Ibuprofen lysine inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. Reduced prostaglandin levels lower inflammation, pain signaling, and fever responses, resulting in analgesic and anti‑inflammatory effects at the site of tissue irritation.

Side Effects

Adverse reactions may range from mild to severe and should be monitored during therapy.

Common Side Effects

  • Nausea: mild stomach upset or queasiness.
  • Dyspepsia: indigestion or heartburn.
  • Headache: occasional worsening of head pain.
  • Dizziness: transient light‑headedness.
  • Diarrhoea: loose stools.
  • Rash: mild skin irritation.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: black stools or vomiting blood.
  • Allergic reaction: swelling, hives, or difficulty breathing.
  • Renal impairment: reduced urine output or swelling of limbs.
  • Liver enzyme elevation: abnormal liver function tests.
  • Cardiovascular events: increased risk of heart attack or stroke in susceptible individuals.

Precautions & Warnings

Before using Migraine Pain Relief, consider the following safety measures.

  • Gastrointestinal risk: assess history of ulcers or bleeding before initiating therapy.
  • Renal function: monitor kidney function in patients with existing renal disease.
  • Cardiovascular caution: avoid long‑term high‑dose use in patients with heart disease.
  • Pregnancy trimester: avoid use in the third trimester due to fetal risk.
  • Concomitant anticoagulants: use with caution when combined with blood thinners.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, and protect from moisture.

Avoid Interactions

Ibuprofen can interact with several drug classes, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs or aspirin: heightened gastrointestinal toxicity.
  • Corticosteroids: amplified ulcer risk.
  • Lithium: elevated lithium serum levels.
  • Methotrexate: reduced clearance leading to toxicity.

Moderate Interactions (Monitor Closely):\n- ACE inhibitors or ARBs: possible reduction in renal function.

  • Diuretics: potential for decreased kidney perfusion.
  • SSRIs or SNRIs: additive bleeding risk.
  • Antihypertensives: may blunt blood pressure‑lowering effect.
  • Cyclosporine: increased nephrotoxicity risk.

Frequently Asked Questions

Migraine Pain Relief contains ibuprofen lysine and is intended to alleviate migraine attacks and other types of headache. By reducing inflammation and pain signaling, it helps adults experience less severe migraine symptoms and improves functional ability during an episode.

Ibuprofen blocks the cyclooxygenase enzymes COX‑1 and COX‑2, which are responsible for producing prostaglandins that promote inflammation, pain, and fever. Lower prostaglandin levels diminish the inflammatory response in the cranial blood vessels, thereby reducing migraine pain and associated discomfort.

The specific dose of Migraine Pain Relief is determined by a qualified prescriber based on the individual’s medical condition, age, and response to therapy. Patients should follow the healthcare professional’s instructions and not exceed the recommended amount.

Safety data for ibuprofen in pregnancy are limited, and use is generally avoided in the third trimester because of potential fetal risks. Breastfeeding mothers should consult a healthcare provider, as ibuprofen can pass into breast milk in small amounts. Professional guidance is essential before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, confirming trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Compared with triptans, which target serotonin receptors, ibuprofen offers a non‑specific anti‑inflammatory approach and is available over the counter. It may be less effective for severe migraine attacks but provides a convenient, lower‑cost option for mild to moderate episodes, often used in combination with other therapies under medical advice.

Store the tablets at ambient temperature, preferably below 25 °C. Keep them in the original container, protect from moisture and direct sunlight, and keep out of reach of children to maintain product stability and potency.

Migraine Pain Relief is taken orally with a full glass of water. It can be taken with or without food, though taking it with food may reduce stomach upset. The tablet should be swallowed whole and not chewed or crushed.

Serious risks include gastrointestinal bleeding, ulcer formation, severe allergic reactions (anaphylaxis), renal impairment, and increased cardiovascular events such as heart attack or stroke, especially with prolonged high‑dose use or in patients with pre‑existing risk factors.

Individuals with a known allergy to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or in the third trimester of pregnancy should avoid this medication. Consultation with a healthcare professional is required for any contraindications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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