Product image of Migrapen (Sumatriptan) supplied by GNH India

Migrapen

Active Ingredient:
Sumatriptan
Origin:
EU

Migrapen (Sumatriptan)

Sumatriptan, the active ingredient in Migrapen, is a Triptan (5‑HT1B/1D receptor agonist) presented as a subcutaneous injection for subcutaneous use. It is indicated for the acute treatment of migraine attacks in adult patients. The formulation is designed for rapid absorption, helping to relieve headache and associated migraine symptoms such as nausea, photophobia, and phonophobia.

GNH India supplies Migrapen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality manufacturing standards and through reliable global distribution.

Manufacturer / TM Owner

Lupin Europe Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Sumatriptan acts on the serotonergic pathway to treat migraine and related headache disorders.
  • Migraine with aura: provides rapid relief of headache and associated neurological symptoms.
  • Migraine without aura: reduces pain intensity and duration of attacks.
  • Cluster headache: aborts acute cluster headache episodes when administered promptly.

How It Works

  • Sumatriptan selectively binds to 5‑HT1B and 5‑HT1D receptors on intracranial blood vessels and trigeminal nerve terminals. Activation of 5‑HT1B receptors induces cranial vasoconstriction, while 5‑HT1D stimulation inhibits release of vasoactive neuropeptides such as CGRP, substance P, and neurokinin A, thereby interrupting the pain signaling cascade responsible for migraine.

Side Effects

Sumatriptan may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Chest discomfort or tightness
  • Tingling or numbness in fingers or face
  • Nausea

Serious or Rare Side Effects

  • Coronary artery spasm or myocardial ischemia
  • Serotonin syndrome when combined with other serotonergic agents
  • Anaphylactic reaction

Precautions & Warnings

  • When prescribing Migrapen, consider the following precautions.
  • Cardiovascular assessment: avoid use in patients with uncontrolled coronary artery disease or recent myocardial infarction.
  • Medication review: assess concomitant use of other serotonergic drugs to reduce risk of serotonin syndrome.
  • Pregnancy considerations: prescribe only if potential benefit justifies potential risk to the fetus.
  • Age restrictions: safety and efficacy have not been established in children or adolescents.
  • Drug interaction vigilance: monitor for interactions with ergot alkaloids and monoamine oxidase inhibitors.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze.

Avoid Interactions

Sumatriptan can interact with several medication classes; awareness helps prevent adverse events.

Major Interactions (Avoid)

  • MAO inhibitors: risk of severe hypertension and serotonin syndrome.
  • Other triptans: additive vasoconstrictive effect may precipitate cardiovascular events.
  • Ergot alkaloids: combined vasoconstriction can lead to ischemia.
  • SSRIs, SNRIs, or other serotonergic agents: increased chance of serotonin syndrome.
  • Linezolid: potential for serotonin syndrome.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may enhance hypotensive effect.
  • CYP3A4 inhibitors (e.g., ketoconazole): may increase sumatriptan plasma levels.

Frequently Asked Questions

Migrapen contains sumatriptan, a medication indicated for the acute treatment of migraine attacks in adults. It helps relieve headache pain and associated symptoms such as nausea, sensitivity to light, and sound when taken at the onset of a migraine episode.

Sumatriptan works by selectively activating 5‑HT1B and 5‑HT1D serotonin receptors in the brain. This causes constriction of dilated cranial blood vessels and blocks the release of inflammatory neuropeptides, interrupting the cascade that generates migraine pain.

The dose of Migrapen is determined by a qualified prescriber based on the patient’s clinical condition, prior response to therapy, and any relevant medical factors. Specific dosing instructions are provided on the prescription label and should not be altered without medical guidance.

Safety data for sumatriptan in pregnancy and lactation are limited. It should be used during pregnancy only if the potential benefit justifies any potential risk to the fetus, and breastfeeding mothers should consult their healthcare professional before use.

To request Migrapen, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Migrapen (sumatriptan) belongs to the triptan class, which specifically targets serotonin receptors to abort migraine attacks. Compared with non‑specific analgesics, triptans provide faster and more complete relief of migraine symptoms, but they are contraindicated in certain cardiovascular conditions where other treatments may be preferred.

Migrapen should be stored at 2‑8 °C (refrigerated). Keep the product in its original packaging, protect it from light, and avoid freezing or shaking the vial to maintain stability and potency.

Migrapen is supplied as a sterile solution for subcutaneous injection. It is administered by a healthcare professional or, when appropriate, by the patient using a pre‑filled syringe, typically into the abdomen or thigh, at the first sign of a migraine.

The most serious risks include coronary artery spasm or myocardial ischemia, severe hypertension, serotonin syndrome when combined with other serotonergic drugs, and rare anaphylactic reactions. Patients should seek immediate medical attention if they experience chest pain, severe headache, or signs of an allergic reaction.

Migrapen is contraindicated in patients with uncontrolled coronary artery disease, recent myocardial infarction, severe hypertension, peripheral vascular disease, or a history of stroke. It should also be avoided in individuals taking ergot alkaloids or monoamine oxidase inhibitors, and in patients with known hypersensitivity to sumatriptan.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.