Product image of Migraspirina (Acetylsalicylic Acid) supplied by GNH India

Migraspirina

Active Ingredient:
Acetylsalicylic Acid
Origin:
EU

Migraspirina (Acetylsalicylic Acid)

Acetylsalicylic Acid, the active ingredient in Migraspirina, is a nonsteroidal anti-inflammatory drug presented as an oral tablet for oral use. It provides analgesic, antipyretic, anti‑inflammatory and antiplatelet effects for adults experiencing mild to moderate pain, fever, inflammation or requiring cardiovascular prophylaxis.

GNH India supplies Migraspirina as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bayer Portugal Lda

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Indications & Clinical Uses

Migraspirina, an NSAID, is used to manage several common conditions by reducing inflammation and platelet aggregation.

  • Mild to moderate pain: provides analgesic relief in headaches, musculoskeletal aches and minor injuries.
  • Fever: lowers elevated body temperature in acute febrile states.
  • Inflammation: diminishes swelling and discomfort associated with inflammatory processes.
  • Cardiovascular prophylaxis: helps prevent myocardial infarction by inhibiting platelet aggregation in at‑risk patients.

How It Works

  • Acetylsalicylic Acid irreversibly inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, blocking the conversion of arachidonic acid to prostaglandins and thromboxane A2. This reduction in prostaglandin synthesis decreases pain, fever, and inflammation, while the inhibition of thromboxane A2 limits platelet aggregation, providing antiplatelet protection.

Side Effects

Adverse reactions to Migraspirina can vary from mild to severe and may require medical attention.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia or abdominal pain.
  • Heartburn: mild burning sensation in the chest.
  • Bleeding gums: easy bruising of oral mucosa.
  • Rash: mild skin irritation.

Serious or Rare Side Effects

  • Gastrointestinal ulcer or bleeding: severe stomach or intestinal hemorrhage.
  • Severe allergic reaction: anaphylaxis, angioedema, or bronchospasm.
  • Hemorrhagic stroke: bleeding in the brain.
  • Reye's syndrome: rare but serious condition in children.

Precautions & Warnings

Before using Migraspirina, consider the following precautions to minimize risk.

  • Assess bleeding risk: avoid in patients with active ulcers or coagulopathy.
  • Avoid in known aspirin allergy: discontinue immediately if hypersensitivity occurs.
  • Use caution in asthma: may trigger bronchospasm in susceptible individuals.
  • Limit use in renal impairment: monitor kidney function regularly.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Migraspirina can interact with several medicines; some combinations should be avoided while others need careful monitoring.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin, direct oral anticoagulants): increased bleeding risk.
  • Selective serotonin reuptake inhibitors (SSRIs) and SNRIs: heightened hemorrhagic potential.
  • Corticosteroids: additive gastrointestinal ulcer risk.
  • Methotrexate: reduced clearance leading to toxicity.

Moderate Interactions (Monitor Closely)

  • Other NSAIDs: additive renal and gastrointestinal effects.
  • Blood pressure medications (e.g., ACE inhibitors, diuretics): may diminish antihypertensive response.
  • Lithium: aspirin may increase lithium serum levels.

Frequently Asked Questions

Migraspirina is indicated for the relief of mild to moderate pain such as headaches, muscle aches, and minor injuries; for the reduction of fever in acute febrile episodes; for the control of inflammation associated with conditions like arthritis; and for cardiovascular prophylaxis to help prevent heart attacks by inhibiting platelet aggregation.

Acetylsalicylic acid works by irreversibly blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for the production of prostaglandins and thromboxane A2. This inhibition lowers the levels of these mediators, resulting in reduced pain, fever, inflammation, and decreased platelet clumping.

The appropriate dose of Migraspirina is determined by a qualified prescriber based on the specific indication, patient age, weight, and overall health status. Patients should follow the healthcare professional’s instructions and never adjust the dose on their own.

Safety of Migraspirina during pregnancy or lactation has not been definitively established. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using this medication.

To order Migraspirina, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Migraspirina contains the same active ingredient, acetylsalicylic acid, found in other aspirin brands, offering comparable analgesic, antipyretic, anti‑inflammatory and antiplatelet effects. Compared with non‑aspirin NSAIDs, it has a well‑characterised antiplatelet profile but shares similar gastrointestinal risk, making individual patient factors important when selecting therapy.

Migraspirina should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in their original packaging, protect them from moisture, direct sunlight and excessive heat to maintain product stability.

Migraspirina is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with food may reduce the chance of stomach irritation. Patients should swallow tablets whole and not crush or chew them unless directed otherwise by a healthcare professional.

The most serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, hemorrhagic stroke, and, in children and teenagers with viral infections, the rare but potentially fatal Reye's syndrome. Prompt medical attention is required if any of these serious events are suspected.

Migraspirina should be avoided by individuals with a known hypersensitivity to aspirin or other NSAIDs, those with active gastrointestinal bleeding or ulcer disease, patients with severe renal or hepatic impairment, and anyone who has experienced a previous severe allergic reaction to acetylsalicylic acid. Consultation with a healthcare professional is essential before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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