Product image of Mikafungin Teva (Micafungin Sodium) supplied by GNH India

Mikafungin Teva

Active Ingredient:
Micafungin Sodium
Origin:
EU

Mikafungin Teva (Micafungin Sodium)

Micafungin Sodium, the active ingredient in Mikafungin Teva, is an echinocandin presented as an injection solution for intravenous use. It is indicated for the treatment of serious systemic fungal infections, including invasive candidiasis, esophageal candidiasis, Candida peritonitis, and febrile neutropenia associated with fungal infection in immunocompromised patients.

GNH India supplies Mikafungin Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres and pharmacies worldwide, providing reliable cold‑chain logistics and regulatory support to meet global distribution.

Manufacturer / TM Owner

Teva B.V

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Micafungin Sodium is used to treat fungal infections by inhibiting cell‑wall synthesis.
  • Invasive candidiasis: effective for bloodstream and deep‑tissue Candida infections, reducing mortality in high‑risk patients.
  • Esophageal candidiasis: clears mucosal Candida lesions and relieves dysphagia.
  • Candida peritonitis: resolves intra‑abdominal Candida infection in postoperative or peritoneal dialysis patients.
  • Febrile neutropenia (fungal): provides rapid antifungal coverage in neutropenic patients with suspected invasive fungal disease.

How It Works

  • Micafungin Sodium inhibits the fungal enzyme 1,3‑β‑D‑glucan synthase, which is essential for synthesizing β‑glucan, a critical component of the fungal cell wall. By blocking this pathway, the drug weakens the cell wall, leading to osmotic instability and cell lysis, while having minimal effect on human cells that lack this enzyme.

Side Effects

Common Side Effects

  • Infusion‑related reactions such as flushing or chills.
  • Mild gastrointestinal symptoms including nausea or abdominal discomfort.
  • Transient elevation of liver enzymes (ALT, AST).
  • Headache or dizziness.
  • Rash or mild pruritus.

Serious or Rare Side Effects

  • Severe hepatotoxicity or hepatic failure.
  • Anaphylactic or severe allergic reactions.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Acute renal impairment.
  • Cardiac arrhythmias or hypotension.

Precautions & Warnings

Before initiating therapy, consider the following precautions:

  • Monitor liver function tests: baseline and periodic assessment recommended.
  • Assess renal function: dose adjustment may be needed in severe impairment.
  • Evaluate for hypersensitivity: discontinue if signs of severe allergic reaction appear.
  • Use caution in patients with pre‑existing hepatic disease.
  • Avoid concomitant use with strong CYP3A4 inducers that may reduce exposure.

Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Micafungin Sodium may interact with several drug classes.

Major Interactions (Avoid)

  • Co‑administration with strong CYP3A4 inducers (e.g., rifampin) can markedly reduce micafungin exposure.
  • Concurrent use with other echinocandins may increase risk of additive toxicity.

Moderate Interactions (Monitor Closely)

  • Combination with azole antifungals (e.g., fluconazole) may require liver enzyme monitoring.
  • Use with immunosuppressants such as tacrolimus or cyclosporine may necessitate dose adjustments.
  • Concurrent hepatotoxic agents (e.g., acetaminophen high doses) should be monitored for liver safety.

Frequently Asked Questions

Mikafungin Teva is an intravenous antifungal medication used to treat serious systemic fungal infections such as invasive candidiasis, esophageal candidiasis, Candida peritonitis, and febrile neutropenia associated with fungal infection, particularly in immunocompromised or critically ill patients.

Micafungin Sodium belongs to the echinocandin class and works by inhibiting the fungal enzyme 1,3‑β‑D‑glucan synthase. This blocks the synthesis of β‑glucan, an essential component of the fungal cell wall, leading to cell wall weakness, osmotic instability and ultimately fungal cell death.

The specific dose and infusion rate of Mikafungin Teva are determined by the prescribing clinician based on the patient’s infection type, severity, weight, renal and hepatic function, and other clinical factors. The prescriber sets the appropriate regimen.

Safety data for Micafungin Sodium in pregnancy and lactation are limited. The drug should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision should be made by a qualified healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain logistics if needed) and any required import documentation.

Mikafungin, as an echinocandin, offers a mechanism distinct from azoles and polyenes, providing potent activity against most Candida species with a favorable safety profile. Compared with other echinocandins such as caspofungin or anidulafungin, micafungin has similar efficacy but may differ in dosing frequency and drug‑interaction potential.

Mikafungin Teva must be stored refrigerated at 2‑8 °C. Keep the vials in their original packaging, protect them from light, and do not freeze or shake the solution. Once reconstituted, use according to the manufacturer’s stability guidelines.

The product is supplied as a sterile injection solution for intravenous infusion. It is typically reconstituted with a compatible diluent, then administered over a prescribed infusion period, usually ranging from 30 to 60 minutes, under aseptic conditions.

Serious adverse events include severe hepatotoxicity, anaphylactic reactions, Stevens‑Johnson syndrome or toxic epidermal necrolysis, acute renal failure, and significant cardiac arrhythmias. Patients should be monitored closely for signs of liver dysfunction, allergic reactions, and any unexpected systemic symptoms.

Mikafungin Teva is contraindicated in patients with a known hypersensitivity to micafungin or any component of the formulation. Caution is advised for individuals with pre‑existing severe hepatic impairment, and it should be used only under specialist supervision in such cases.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.