Product image of Mildison Lipocream (Hydrocortisone) supplied by GNH India

Mildison Lipocream

Active Ingredient:
Hydrocortisone
Origin:
EU

Mildison Lipocream (Hydrocortisone)

Hydrocortisone, the active ingredient in Mildison Lipocream, is a corticosteroid presented as a topical lipocream for cutaneous use. It exerts anti‑inflammatory and antiallergic effects, making it suitable for managing eczema, dermatitis, psoriasis and other allergic skin reactions in patients of various ages.

GNH India supplies Mildison Lipocream as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide, providing reliable bulk and unit‑dose shipments that meet European Union quality standards. The company adheres to stringent quality control and regulatory compliance to ensure product integrity throughout the supply chain.

Manufacturer / TM Owner

Karo Pharma Ab

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Indications & Clinical Uses

  • Hydrocortisone topical cream is employed to control a range of inflammatory and allergic skin disorders.
  • Eczema: reduces redness, itching and swelling associated with atopic dermatitis.
  • Dermatitis: alleviates inflammation and pruritus caused by irritants or allergens.
  • Psoriasis: helps to soften plaques and diminish scaling.
  • Allergic skin reactions: suppresses localized immune response to reduce rash and edema.
  • Seborrheic dermatitis: moderates inflammation and scaling in affected areas.

How It Works

  • Hydrocortisone penetrates the epidermis and binds to intracellular glucocorticoid receptors, forming a complex that translocates to the nucleus. This complex interacts with glucocorticoid response elements on DNA, altering transcription of multiple genes. The result is decreased synthesis of pro‑inflammatory cytokines, prostaglandins and leukotrienes, and inhibition of immune cell migration, producing potent anti‑inflammatory and immunosuppressive effects at the site of application.

Side Effects

Topical hydrocortisone may cause local and, rarely, systemic adverse reactions.

Common Side Effects

  • Skin irritation
  • Burning sensation
  • Itching
  • Dryness

Serious or Rare Side Effects

  • Skin atrophy
  • Telangiectasia
  • Secondary bacterial or fungal infection
  • Adrenal suppression due to systemic absorption
  • Hyperglycemia in susceptible individuals

Precautions & Warnings

When using Mildison Lipocream, follow these safety measures.

  • Apply to intact skin only: avoid broken or infected areas.
  • Limit duration of use: do not exceed recommended treatment period without medical review.
  • Avoid use on face, genitalia or skin folds unless directed by a clinician.
  • Do not cover with occlusive dressings unless advised, as this may increase absorption.
  • Monitor for signs of systemic effects: unusual fatigue, weight change, or hormonal disturbances.
  • Store at room temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Hydrocortisone can interact with other medicines; consider the following.

Major Interactions (Avoid)

  • Concurrent systemic corticosteroids: may increase risk of systemic glucocorticoid effects.
  • Potent CYP3A4 inhibitors (e.g., ketoconazole): can raise systemic absorption of hydrocortisone.
  • Immunosuppressive agents (e.g., cyclosporine): may enhance local immunosuppression and infection risk.

Moderate Interactions (Monitor Closely)

  • Use with other topical steroids: cumulative potency may cause skin atrophy.
  • Occlusive dressings: increase percutaneous absorption, monitor for systemic signs.
  • Antiviral or antifungal topical agents: may alter skin barrier, affecting hydrocortisone efficacy.

Frequently Asked Questions

Mildison Lipocream is a topical hydrocortisone cream indicated for the relief of inflammation, itching and redness associated with skin conditions such as eczema, various forms of dermatitis, psoriasis and other allergic skin reactions.

Hydrocortisone penetrates the skin and binds to intracellular glucocorticoid receptors. The resulting complex alters gene transcription, decreasing production of pro‑inflammatory mediators and suppressing immune‑cell activity, which reduces local inflammation and allergic responses.

The prescribed dose is determined by the treating clinician. Typically, a thin layer is applied to the affected area once or twice daily, but the exact frequency, amount and treatment duration should follow the healthcare professional’s instructions.

Safety data for topical hydrocortisone during pregnancy and lactation are limited. It should be used only if the potential benefit outweighs any possible risk, and the decision should be made in consultation with a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Mildison Lipocream contains hydrocortisone, a low‑ to medium‑potency corticosteroid. Compared with higher‑potency agents such as betamethasone or clobetasol, it offers a milder anti‑inflammatory effect, which may be preferable for sensitive areas or for short‑term use, while still providing effective symptom control for many common dermatoses.

Store the cream at room temperature, preferably below 25 °C. Keep it in the original container, protect it from moisture, direct sunlight and extreme heat. Do not freeze the product, and ensure the cap is tightly closed when not in use.

Apply a thin, even layer of the cream to clean, dry skin on the affected area. Gently rub it in until fully absorbed. Avoid contact with eyes, mucous membranes and open wounds unless directed by a clinician.

Serious adverse events, although uncommon, include skin atrophy, development of telangiectasia, secondary bacterial or fungal infections, and systemic effects such as adrenal suppression or hyperglycemia when large amounts are absorbed. Promptly report any unusual symptoms to a healthcare professional.

Mildison Lipocream is contraindicated in individuals with known hypersensitivity to hydrocortisone or any excipients, and should be avoided on skin infected with viruses (e.g., herpes simplex), on extensive broken skin, or in patients where systemic corticosteroid exposure is undesirable without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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